Effect of organic and in-organic chromium supplementation on growth performance and genotoxicity of Labeo rohita

In aquaculture industry, the aim of feed formulation is to provide the fish with feasible diet to enhance their body. Carbohydrates supplemented with chromium compounds (organic and in-organic) are major energy currencies for biological machinery of fish. Here, this article presents a description that emphasizes the effect of chromium picolinate (organic) and chromium chloride hexahydrate (in-organic) on growth execution and genotoxicity of Labeorohita. Seven groups (each with a replica) with 30 Labeorohita fingerlings were formed: a control group, three groups were supplemented with chromium chloride Hexahydrate (0.3, 0.5 and 0.6 mg kg(-1)) and three groups were supplemented with Cr-Pic, 0.3, 0.5 and 0.6 mg kg(-1)) respectively. The experimental group T4 fortified with (Cr-Pic) along with carbohydrates by dose of 0.3 mg/kg demonstrated significant results (P < 0.05). Superior growth for Labeo rohita was observed as compared to control and other experimental groups. Minimum growth trend was observed in group T5 (CP-0.5 mg/kg), T6 (CP-0.6 mg/kg) and T7 (control) respectively. Comet assay results indicated the dose and Cr related (organic or in-organic) genetic damage in fish erythrocytes. Hence, maximum comet parameters (Tail length, Tail DNA and Olive Tail Moment) were observed in (in-organic Cr) by 0.3 mg/kg concentration. This study suggested the toxicity corresponding to inorganic Cr but organic Cr could be used as growth promoter if so. Overall results demonstrated supplementation of organic chromium compounds by 0.3 mg/kg should be reconsidered for growth. This drive of research address the fish farmers to utilize the feed supplemented with organic Cr compounds which is most appropriate to provide sustainable yield as part of increment in growth performance and beneficial health effects for consumers on indices to reduce the toxicity risks. (C) 2019 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.