期刊
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
卷 26, 期 2, 页码 395-401出版社
ELSEVIER
DOI: 10.1016/j.sjbs.2018.11.008
关键词
Codonopsis foetens; Deferribacteres; Intestine tumor; 16S rRNA sequence
类别
资金
- National Natural Science Foundation of China (NSFC) [31860254/61363061/31660029]
- Advanced and Characteristic Key Biological Disciplines of Yunnan Province [50097505]
- Scientific and Technological Innovation Team Construction Project for Protection and Utilization of Under-forest Biological Resources [51400605]
As a complicated micro-ecosystem, gut microbes are closely related to metabolic disease, immune disease and tumor (such as constipation. Long-term constipation would cause intestinal mucosal injury, enteritis, ileus, etc., thus inducing intestine cancer). In this research, intestine cancer model group and Codonopsis foetens treatment group were successfully constructed, and the variation of intestinal microbes were analyzed by 16S rRNA sequence. Results showed that there were changes in bacteria abundance of Firmicutes, Bacteroidetes, Proteobacteria, Deferribacteres, Tenericutes, and Actinobacteria, etc. Codonopsis foetens could directly or indirectly affect the growth and metabolism of Deferribacteres by altering the nutritional ingredient and pH value of intestine medium, thus affecting the occurrence and development of intestinal microbes. (C) 2018 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.
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