Physiological aspects of Toll-like receptor 4 activation in sepsis-induced acute kidney injury

Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis*

(2016) Dan Li et al.   CRITICAL CARE MEDICINE

Pretreatment of Sialic Acid Efficiently Prevents Lipopolysaccharide-Induced Acute Renal Failure and Suppresses TLR4/gp91-Mediated Apoptotic Signaling

(2016) Shih-Ping Hsu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Autophagy Limits Endotoxemic Acute Kidney Injury and Alters Renal Tubular Epithelial Cell Cytokine Expression

(2016) Jeremy S. Leventhal et al.   PLoS One

Acute Kidney Injury Requiring Dialysis in Severe Sepsis

(2015) Ankit Sakhuja et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cortical and Medullary Tissue Perfusion and Oxygenation in Experimental Septic Acute Kidney Injury

(2015) Paolo Calzavacca et al.   CRITICAL CARE MEDICINE

Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study

(2015) Eric A. J. Hoste et al.   INTENSIVE CARE MEDICINE

Vitamin D3 pretreatment alleviates renal oxidative stress in lipopolysaccharide-induced acute kidney injury

(2015) Shen Xu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Reduction of Tubular Flow Rate as a Mechanism of Oliguria in the Early Phase of Endotoxemia Revealed by Intravital Imaging

(2015) D. Nakano et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

(2015) Rajesh Rajaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How bold is blood oxygenation level-dependent (BOLD) magnetic resonance imaging of the kidney? Opportunities, challenges and future directions

(2014) T. Niendorf et al.   Acta Physiologica

Proximal Tubule Toll-Like Receptor 4 Expression Linked to Inflammation and Apoptosis following Hypoxia/Reoxygenation Injury

(2014) Xiu-Juan Liu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI

(2014) A. Wonnacott et al.   Clinical Journal of the American Society of Nephrology

Expression and cellular distribution of TLR4, MyD88, and NF-κB in diabetic renal tubulointerstitial fibrosis, in vitro and in vivo

(2014) Ping Liu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The Macrophage Mediates the Renoprotective Effects of Endotoxin Preconditioning

(2014) T. Hato et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

High versus Low Blood-Pressure Target in Patients with Septic Shock

(2014) Pierre Asfar et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Duration of Hypotension Determines the Evolution of Bacteremia-Induced Acute Kidney Injury in the Intensive Care Unit

(2014) Karin Janssen van Doorn et al.   PLoS One

Mechanisms of acute kidney injury

(2013) Pontus B. Persson   Acta Physiologica

Neurohormonal interactions on the renal oxygen delivery and consumption in haemorrhagic shock-induced acute kidney injury

(2013) M. Hultström   Acta Physiologica

Mechanisms of Cardiac and Renal Dysfunction in Patients Dying of Sepsis

(2013) Osamu Takasu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Renal Histopathology During Experimental Septic Acute Kidney Injury and Recovery*

(2013) Christoph Langenberg et al.   CRITICAL CARE MEDICINE

Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis

(2013) Steven M. Opal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Complement Factor B Is the Downstream Effector of TLRs and Plays an Important Role in a Mouse Model of Severe Sepsis

(2013) L. Zou et al.   JOURNAL OF IMMUNOLOGY

Epithelial transport during septic acute kidney injury

(2013) E. D. Morrell et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Small Interfering RNA Targeting Toll-Like Receptor 9 Protects Mice against Polymicrobial Septic Acute Kidney Injury

(2013) Lixia Liu et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Unified Theory of Sepsis-Induced Acute Kidney Injury

(2013) Hernando Gomez et al.   SHOCK

Age-dependent Role of Microvascular Endothelial and Polymorphonuclear Cells in Lipopolysaccharide-induced Acute Kidney Injury

(2012) Francis M. Wulfert et al.   ANESTHESIOLOGY

Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis*

(2012) Ken Ishikawa et al.   CRITICAL CARE MEDICINE

Measurement of renal blood flow by phase-contrast magnetic resonance imaging during septic acute kidney injury

(2012) John R. Prowle et al.   CRITICAL CARE MEDICINE

Distinct pathophysiologic mechanisms of septic acute kidney injury

(2012) So-Young Lee et al.   CRITICAL CARE MEDICINE

Toll-like Receptor 2 Is Required for LPS-induced Toll-like Receptor 4 Signaling and Inhibition of Ion Transport in Renal Thick Ascending Limb

(2012) David W. Good et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4

(2012) R. Allam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis

(2012) Angela Castoldi et al.   PLoS One

Renal neutrophil gelatinase associated lipocalin expression in lipopolysaccharide-induced acute kidney injury in the rat

(2012) Mei Han et al.   BMC Nephrology

The effects of isoflurane anesthesia and mechanical ventilation on renal function during endotoxemia

(2011) R. FRITHIOF et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury

(2011) Zhen Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Uncovering the pathway of sepsis-induced renal tubular dysfunction. Focus on “Basolateral LPS inhibits NHE3 and HCO3− absorption through TLR4/MyD88-dependent ERK activation in medullary thick ascending limb”

(2011) Francesca Di Sole et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Basolateral LPS inhibits NHE3 and HCO3− absorption through TLR4/MyD88-dependent ERK activation in medullary thick ascending limb

(2011) Bruns A. Watts et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Toll-Like Receptor 4 Inhibitor TAK-242 Attenuates Acute Kidney Injury in Endotoxemic Sheep

(2011) Johan Fenhammar et al.   ANESTHESIOLOGY

Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death

(2011) Alvaro Becerra et al.   CARDIOVASCULAR RESEARCH

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats

(2011) Matthieu Legrand et al.   INTENSIVE CARE MEDICINE

Acute kidney injury in patients with influenza A (H1N1) 2009

(2011) Ville Pettilä et al.   INTENSIVE CARE MEDICINE

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

(2011) Mei Tran et al.   JOURNAL OF CLINICAL INVESTIGATION

Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment

(2011) R. Kalakeche et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4

(2011) Jianlin Chen et al.   KIDNEY INTERNATIONAL

Acute kidney injury after cardiac arrest

(2011) Horng-Ruey Chua et al.   RESUSCITATION

Microvascular and Interstitial Oxygen Tension in the Renal Cortex and Medulla Studied in A 4-H Rat Model of LPS-Induced Endotoxemia

(2011) Alex Dyson et al.   SHOCK

The Decline of Autophagy Contributes to Proximal Tubular Dysfunction During Sepsis

(2011) Hsiu-Wen Hsiao et al.   SHOCK

The endothelin receptor antagonist tezosentan improves renal microcirculation in a porcine model of endotoxemic shock

(2010) J. FENHAMMAR et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis*

(2010) Todd W. Rice et al.   CRITICAL CARE MEDICINE

Acute renal failure is NOT an “acute renal success”—a clinical study on the renal oxygen supply/demand relationship in acute kidney injury

(2010) Bengt Redfors et al.   CRITICAL CARE MEDICINE

The impact of experimental hypoperfusion on subsequent kidney function

(2010) Takao Saotome et al.   INTENSIVE CARE MEDICINE

Angiotensin II Type 1 Receptor Antagonism Attenuates Abnormalities in Dynamic Renal Blood Flow Autoregulation in Rats with Endotoxin-Induced Acute Kidney Injury

(2010) Nicoletta Nitescu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

The role of Toll-like receptors in renal diseases

(2010) Anna Gluba et al.   Nature Reviews Nephrology

Phase 2 trial of eritoran tetrasodium (E5564), a Toll-like receptor 4 antagonist, in patients with severe sepsis*

(2009) Mark Tidswell et al.   CRITICAL CARE MEDICINE

Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier

(2009) Rahul D. Pawar et al.   IMMUNOLOGY

Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration

(2009) Nicolas Lerolle et al.   INTENSIVE CARE MEDICINE

LOW-DOSE DEXAMETHASONE-SUPPLEMENTED FLUID RESUSCITATION REVERSES ENDOTOXIN-INDUCED ACUTE RENAL FAILURE AND PREVENTS CORTICAL MICROVASCULAR HYPOXIA

(2009) Tanja Johannes et al.   SHOCK

TLR4 Signaling Mediates Inflammation and Tissue Injury in Nephrotoxicity

(2008) B. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury

(2008) Wilco P. Pulskens et al.   PLoS One

NONRESUSCITATED ENDOTOXEMIA INDUCES MICROCIRCULATORY HYPOXIC AREAS IN THE RENAL CORTEX IN THE RAT

(2008) Tanja Johannes et al.   SHOCK