Gi/o protein-coupled receptors in dopamine neurons inhibit the sodium leak channel NALCN

Nucleus Accumbens Subnuclei Regulate Motivated Behavior via Direct Inhibition and Disinhibition of VTA Dopamine Subpopulations

(2018) Hongbin Yang et al.   NEURON

GABAB receptors in neocortical and hippocampal pyramidal neurons are coupled to different potassium channels

(2017) Jean-Didier Breton et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopamine Inhibition Differentially Controls Excitability of Substantia Nigra Dopamine Neuron Subpopulations through T-Type Calcium Channels

(2017) Rebekah C. Evans et al.   JOURNAL OF NEUROSCIENCE

Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn

(2017) Szu-Ying Yeh et al.   NEURON

Dopamine negatively modulates the NCA ion channels in C. elegans

(2017) Irini Topalidou et al.   PLoS Genetics

NALCN channelopathies

(2016) Eric G. Bend et al.   NEUROLOGY

Selective Ablation of GIRK Channels in Dopamine Neurons Alters Behavioral Effects of Cocaine in Mice

(2016) Nora M McCall et al.   NEUROPSYCHOPHARMACOLOGY

Calcium Release from Stores Inhibits GIRK

(2016) Paul F. Kramer et al.   Cell Reports

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

(2016) Andrew Lutas et al.   eLife

Cooperative regulation by G proteins and Na+ of neuronal GIRK2 K+ channels

(2016) Weiwei Wang et al.   eLife

NovelNALCNvariant: altered respiratory and circadian rhythm, anesthetic sensitivity

(2016) Bernarda Lozic et al.   Annals of Clinical and Translational Neurology

De Novo Mutations in NALCN Cause a Syndrome Characterized by Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay

(2015) Jessica X. Chong et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Conserved Bicycle Model for Circadian Clock Control of Membrane Excitability

(2015) Matthieu Flourakis et al.   CELL

Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons

(2015) T. Kimm et al.   JOURNAL OF NEUROSCIENCE

The NCA sodium leak channel is required for persistent motor circuit activity that sustains locomotion

(2015) Shangbang Gao et al.   Nature Communications

Compensatory T-type Ca2+ channel activity alters D2-autoreceptor responses of Substantia nigra dopamine neurons from Cav1.3 L-type Ca2+ channel KO mice

(2015) Christina Poetschke et al.   Scientific Reports

Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium

(2015) Stephanie C Gantz et al.   eLife

The role of D2-autoreceptors in regulating dopamine neuron activity and transmission

(2014) C.P. Ford   NEUROSCIENCE

Spontaneous Inhibitory Synaptic Currents Mediated by a G Protein-Coupled Receptor

(2013) Stephanie C. Gantz et al.   NEURON

Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors

(2012) A. Anzalone et al.   JOURNAL OF NEUROSCIENCE

Optical Control of Endogenous Proteins with a Photoswitchable Conditional Subunit Reveals a Role for TREK1 in GABAB Signaling

(2012) Guillaume Sandoz et al.   NEURON

Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum

(2012) Nicolas X. Tritsch et al.   NEURON

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Contribution of Kv1.2 Voltage-gated Potassium Channel to D2 Autoreceptor Regulation of Axonal Dopamine Overflow

(2011) Stephanie Fulton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors

(2011) Estefanía P Bello et al.   NATURE NEUROSCIENCE

Sodium Leak Channels in Neuronal Excitability and Rhythmic Behaviors

(2011) Dejian Ren   NEURON

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

How Modeling Can Reconcile Apparently Discrepant Experimental Results: The Case of Pacemaking in Dopaminergic Neurons

(2011) Guillaume Drion et al.   PLoS Computational Biology

Pacemaking in Dopaminergic Ventral Tegmental Area Neurons: Depolarizing Drive from Background and Voltage-Dependent Sodium Conductances

(2010) Z. M. Khaliq et al.   JOURNAL OF NEUROSCIENCE

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease

(2010) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

Extracellular Calcium Controls Background Current and Neuronal Excitability via an UNC79-UNC80-NALCN Cation Channel Complex

(2010) Boxun Lu et al.   NEURON

Cellular Mechanisms Underlying Burst Firing in Substantia Nigra Dopamine Neurons

(2009) S. N. Blythe et al.   JOURNAL OF NEUROSCIENCE

GABAB Receptor Activation Inhibits Neuronal Excitability and Spatial Learning in the Entorhinal Cortex by Activating TREK-2 K+ Channels

(2009) Pan-Yue Deng et al.   NEURON

Dynamic, Nonlinear Feedback Regulation of Slow Pacemaking by A-Type Potassium Current in Ventral Tegmental Area Neurons

(2008) Z. M. Khaliq et al.   JOURNAL OF NEUROSCIENCE

Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80

(2008) Boxun Lu et al.   NATURE

Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System

(2008) Stephan Lammel et al.   NEURON