Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

(2018) Saman Hussain et al.   eLife

Identification of a Functionally Unique Family of Penicillin-Binding Proteins

(2017) Michael A. Welsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity

(2017) E. Hesper Rego et al.   NATURE

Lipid II overproduction allows direct assay of transpeptidase inhibition by β-lactams

(2017) Yuan Qiao et al.   Nature Chemical Biology

Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis

(2017) Helene Botella et al.   mBio

Fluorescent D-amino-acids reveal bi-cellular cell wall modifications important for Bdellovibrio bacteriovorus predation

(2017) Erkin Kuru et al.   Nature Microbiology

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

(2017) Jeremy M. Rock et al.   Nature Microbiology

Division site selection linked to inherited cell surface wave troughs in mycobacteria

(2017) Haig A. Eskandarian et al.   Nature Microbiology

Non-classical transpeptidases yield insight into new antibacterials

(2016) Pankaj Kumar et al.   Nature Chemical Biology

β-Lactams against Tuberculosis — New Trick for an Old Dog?

(2016) Andreas H. Diacon et al.   NEW ENGLAND JOURNAL OF MEDICINE

A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis

(2016) Cara C Boutte et al.   eLife

A putative low-molecular-mass penicillin-binding protein (PBP) of Mycobacterium smegmatis exhibits prominent physiological characteristics of dd-carboxypeptidase and beta-lactamase

(2015) Ankita Bansal et al.   MICROBIOLOGY-SGM

Oufti: an integrated software package for high-accuracy, high-throughput quantitative microscopy analysis

(2015) Ahmad Paintdakhi et al.   MOLECULAR MICROBIOLOGY

Peptidoglycan synthesis inMycobacterium tuberculosisis organized into networks with varying drug susceptibility

(2015) Karen J. Kieser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The essential features and modes of bacterial polar growth

(2015) Todd A. Cameron et al.   TRENDS IN MICROBIOLOGY

TRANSIT - A Software Tool for Himar1 TnSeq Analysis

(2015) Michael A. DeJesus et al.   PLoS Computational Biology

Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria

(2015) Karen J. Kieser et al.   PLoS Pathogens

Nonclassical Transpeptidases of Mycobacterium tuberculosis Alter Cell Size, Morphology, the Cytosolic Matrix, Protein Localization, Virulence, and Resistance to  -Lactams

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Reconstitution of Peptidoglycan Cross-Linking Leads to Improved Fluorescent Probes of Cell Wall Synthesis

(2014) Matthew D. Lebar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction

(2014) Yuan Qiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetic characterization of mycobacterial L,D-transpeptidases

(2014) A. N. Sanders et al.   MICROBIOLOGY-SGM

Synthesis of fluorescent D-amino acids and their use for probing peptidoglycan synthesis and bacterial growth in situ

(2014) Erkin Kuru et al.   Nature Protocols

How sisters grow apart: mycobacterial growth and division

(2014) Karen J. Kieser et al.   NATURE REVIEWS MICROBIOLOGY

Rod-like bacterial shape is maintained by feedback between cell curvature and cytoskeletal localization

(2014) T. S. Ursell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division

(2013) Yuriy Rebets et al.   ACS Chemical Biology

In VitroCross-Linking of Mycobacterium tuberculosis Peptidoglycan by l,d-Transpeptidases and Inactivation of These Enzymes by Carbapenems

(2013) Mathilde Cordillot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis

(2013) G. W. Liechti et al.   NATURE

Kinetic Features of L,D-Transpeptidase Inactivation Critical for β-Lactam Antibacterial Activity

(2013) Sébastien Triboulet et al.   PLoS One

In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with FluorescentD-Amino Acids

(2012) Erkin Kuru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inactivation of Mycobacterium tuberculosis l,d-Transpeptidase LdtMt1by Carbapenems and Cephalosporins

(2012) Vincent Dubée et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Is there a place for  -lactams in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis? Synergy between meropenem and amoxicillin/clavulanate

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Meropenem inhibits D,D-carboxypeptidase activity inMycobacterium tuberculosis

(2012) Pradeep Kumar et al.   MOLECULAR MICROBIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Polar growth in the Alphaproteobacterial order Rhizobiales

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Carbapenems: Past, Present, and Future

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Distinct pathways for modification of the bacterial cell wall by non-canonicalD-amino acids

(2011) Felipe Cava et al.   EMBO JOURNAL

Rapid measurement of antituberculosis drug activity in vitro and in macrophages using bioluminescence

(2011) N. Andreu et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

AmpH, a Bifunctional DD-Endopeptidase and DD-Carboxypeptidase of Escherichia coli

(2011) S. M. Gonzalez-Leiza et al.   JOURNAL OF BACTERIOLOGY

Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB

(2011) Dominic Böth et al.   JOURNAL OF MOLECULAR BIOLOGY

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

(2011) B. B. Aldridge et al.   SCIENCE

Processive Movement of MreB-Associated Cell Wall Biosynthetic Complexes in Bacteria

(2011) J. Dominguez-Escobar et al.   SCIENCE

Coupled, Circumferential Motions of the Cell Wall Synthesis Machinery and MreB Filaments in B. subtilis

(2011) E. C. Garner et al.   SCIENCE

The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin

(2010) Radhika Gupta et al.   NATURE MEDICINE

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Thin PDMS Films Using Long Spin Times or Tert-Butyl Alcohol as a Solvent

(2009) John H. Koschwanez et al.   PLoS One

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis

(2009) J.-E. Hugonnet et al.   SCIENCE

The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by L,D-Transpeptidation

(2008) M. Lavollay et al.   JOURNAL OF BACTERIOLOGY

Bacterial Growth and Cell Division: a Mycobacterial Perspective

(2008) E. C. Hett et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS