The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity

Intrinsic Immunity Shapes Viral Resistance of Stem Cells

(2018) Xianfang Wu et al.   CELL

DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection

(2018) Spyridon Stavrou et al.   mBio

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold

(2016) Gavin J. Knott et al.   NUCLEIC ACIDS RESEARCH

DDX3 functions in antiviral innate immunity through translational control of PACT

(2015) Ming-Chih Lai et al.   FEBS Journal

DDX3, a potential target for cancer treatment

(2015) Guus Martinus Bol et al.   Molecular Cancer

RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity

(2015) Fernando Valiente-Echeverría et al.   REVIEWS IN MEDICAL VIROLOGY

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

The Interaction of RNA Helicase DDX3 with HIV-1 Rev-CRM1-RanGTP Complex during the HIV Replication Cycle

(2015) Seyed Hanif Mahboobi et al.   PLoS One

Listeria monocytogenes induces IFN  expression through an IFI16-, cGAS- and STING-dependent pathway

(2014) K. Hansen et al.   EMBO JOURNAL

Independent of Plasmacytoid Dendritic Cell (pDC) infection, pDC Triggered by Virus-Infected Cells Mount Enhanced Type I IFN Responses of Different Composition as Opposed to pDC Stimulated with Free Virus

(2014) Theresa Frenz et al.   JOURNAL OF IMMUNOLOGY

DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

(2013) Anthony Fullam et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Human DDX3 Interacts with the HIV-1 Tat Protein to Facilitate Viral mRNA Translation

(2013) Ming-Chih Lai et al.   PLoS One

Sex and inflammation in respiratory diseases: a clinical viewpoint

(2013) Georges J Casimir et al.   Biology of Sex Differences

DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

(2012) Ricardo Soto-Rifo et al.   EMBO JOURNAL

RIG-I detects infection with liveListeriaby sensing secreted bacterial nucleic acids

(2012) Zeinab Abdullah et al.   EMBO JOURNAL

Conditional Stat1 Ablation Reveals the Importance of Interferon Signaling for Immunity to Listeria monocytogenes Infection

(2012) Elisabeth Kernbauer et al.   PLoS Pathogens

Ly6G + Neutrophils Are Dispensable for Defense against Systemic Listeria monocytogenes Infection

(2011) Chao Shi et al.   JOURNAL OF IMMUNOLOGY

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SF1 and SF2 helicases: family matters

(2010) Margaret E Fairman-Williams et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides

(2010) John-Demian Sauer et al.   INFECTION AND IMMUNITY

Activation of Naive NK Cells in Response to Listeria monocytogenes Requires IL-18 and Contact with Infected Dendritic Cells

(2010) J. Humann et al.   JOURNAL OF IMMUNOLOGY

Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

(2010) Hiroyuki Oshiumi et al.   PLoS One

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection

(2009) G. Yeretssian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes

(2009) Silvia Stockinger et al.   PLoS Pathogens

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL