Deleterious variation shapes the genomic landscape of introgression

Impacts of Recurrent Hitchhiking on Divergence and Demographic Inference in Drosophila

(2018) Jeremy D Lange et al.   Genome Biology and Evolution

Gene expression drives the evolution of dominance

(2018) Christian D. Huber et al.   Nature Communications

Evidence that RNA Viruses Drove Adaptive Introgression between Neanderthals and Modern Humans

(2018) David Enard et al.   CELL

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples

(2017) Bernard Y. Kim et al.   GENETICS

Population-genomic inference of the strength and timing of selection against gene flow

(2017) Simon Aeschbacher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determining the factors driving selective effects of new nonsynonymous mutations

(2017) Christian D. Huber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive introgression from distant Caribbean islands contributed to the diversification of a microendemic adaptive radiation of trophic specialist pupfishes

(2017) Emilie J. Richards et al.   PLoS Genetics

A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy

(2017) Russell Corbett-Detig et al.   PLoS Genetics

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples

(2017) Bernard Y. Kim et al.   GENETICS

The Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans

(2016) Sriram Sankararaman et al.   CURRENT BIOLOGY

Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments

(2016) Rachel M. Gittelman et al.   CURRENT BIOLOGY

Archaic admixture in human history

(2016) Jeffrey D Wall et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives

(2016) Yuval B Simons et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

When Is Selection Effective?

(2016) Simon Gravel   GENETICS

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit

(2016) Casper-Emil T. Pedersen et al.   GENETICS

The Genetic Cost of Neanderthal Introgression

(2016) Kelley Harris et al.   GENETICS

Long-distance dispersal suppresses introgression of local alleles during range expansions

(2016) C E G Amorim et al.   HEREDITY

SLiM 2: Flexible, Interactive Forward Genetic Simulations

(2016) Benjamin C. Haller et al.   MOLECULAR BIOLOGY AND EVOLUTION

Revisiting a classic case of introgression: hybridization and gene flow in Californian sunflowers

(2016) Gregory L. Owens et al.   MOLECULAR ECOLOGY

A genomic perspective on hybridization and speciation

(2016) Bret A. Payseur et al.   MOLECULAR ECOLOGY

Sequencing of the genus Arabidopsis identifies a complex history of nonbifurcating speciation and abundant trans-specific polymorphism

(2016) Polina Yu Novikova et al.   NATURE GENETICS

The Limits of Natural Selection in a Nonequilibrium World

(2016) Yaniv Brandvain et al.   TRENDS IN GENETICS

Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes

(2016) Jerome Kelleher et al.   PLoS Computational Biology

The Strength of Selection against Neanderthal Introgression

(2016) Ivan Juric et al.   PLoS Genetics

When Is Selection Effective?

(2016) Simon Gravel   GENETICS

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit

(2016) Casper-Emil T. Pedersen et al.   GENETICS

The Genetic Cost of Neanderthal Introgression

(2016) Kelley Harris et al.   GENETICS

Functional Organization of the Genome May Shape the Species Boundary in the House Mouse

(2015) Václav Janoušek et al.   MOLECULAR BIOLOGY AND EVOLUTION

Population genomic analysis uncovers African and European admixture inDrosophila melanogasterpopulations from the south-eastern United States and Caribbean Islands

(2015) Joyce Y. Kao et al.   MOLECULAR ECOLOGY

Expansion load: recessive mutations and the role of standing genetic variation

(2015) Stephan Peischl et al.   MOLECULAR ECOLOGY

No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans

(2015) Ron Do et al.   NATURE GENETICS

Estimating the mutation load in human genomes

(2015) Brenna M. Henn et al.   NATURE REVIEWS GENETICS

Evidence for archaic adaptive introgression in humans

(2015) Fernando Racimo et al.   NATURE REVIEWS GENETICS

Obstruction of adaptation in diploids by recessive, strongly deleterious alleles

(2015) Zoe June Assaf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs

(2015) Clare D. Marsden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distance from sub-Saharan Africa predicts mutational load in diverse human genomes

(2015) Brenna M. Henn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postmating reproductive barriers contribute to the incipient sexual isolation of the United States and CaribbeanDrosophila melanogaster

(2015) Joyce Y. Kao et al.   Ecology and Evolution

Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck

(2015) Daniel J. Balick et al.   PLoS Genetics

Contrasting X-Linked and Autosomal Diversity across 14 Human Populations

(2014) Leonardo Arbiza et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Characteristics of Neutral and Deleterious Protein-Coding Variation among Individuals and Populations

(2014) Wenqing Fu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The distribution of deleterious genetic variation in human populations

(2014) Kirk E Lohmueller   CURRENT OPINION IN GENETICS & DEVELOPMENT

Robust Forward Simulations of Recurrent Hitchhiking

(2014) Lawrence H. Uricchio et al.   GENETICS

Evidence for Increased Levels of Positive and Negative Selection on the X Chromosome versus Autosomes in Humans

(2014) Krishna R. Veeramah et al.   MOLECULAR BIOLOGY AND EVOLUTION

Neanderthal Origin of the Haplotypes Carrying the Functional Variant Val92Met in the MC1R in Modern Humans

(2014) Qiliang Ding et al.   MOLECULAR BIOLOGY AND EVOLUTION

Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA

(2014) Emilia Huerta-Sánchez et al.   NATURE

The genomic landscape of Neanderthal ancestry in present-day humans

(2014) Sriram Sankararaman et al.   NATURE

The deleterious mutation load is insensitive to recent population history

(2014) Yuval B Simons et al.   NATURE GENETICS

The Impact of Population Demography and Selection on the Genetic Architecture of Complex Traits

(2014) Kirk E. Lohmueller   PLoS Genetics

Population Growth Inflates the Per-Individual Number of Deleterious Mutations and Reduces Their Mean Effect

(2013) Elodie Gazave et al.   GENETICS

Estimating and interpreting FST: The impact of rare variants

(2013) G. Bhatia et al.   GENOME RESEARCH

Neanderthal Introgression at Chromosome 3p21.31 Was Under Positive Natural Selection in East Asians

(2013) Qiliang Ding et al.   MOLECULAR BIOLOGY AND EVOLUTION

Adaptive introgression in animals: examples and comparison to new mutation and standing variation as sources of adaptive variation

(2013) Philip W. Hedrick   MOLECULAR ECOLOGY

Whole-Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans

(2013) Ferran Casals et al.   PLoS Genetics

Demographic Inference Reveals African and European Admixture in the North American Drosophila melanogaster Population

(2012) P. Duchen et al.   GENETICS

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

The Date of Interbreeding between Neandertals and Modern Humans

(2012) Sriram Sankararaman et al.   PLoS Genetics

The recombination landscape in Arabidopsis thaliana F2 populations

(2011) P A Salomé et al.   HEREDITY

The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

(2011) L. Abi-Rached et al.   SCIENCE

Sex-Averaged Recombination and Mutation Rates on the X Chromosome: A Comment on Labuda et al.

(2010) Kirk E. Lohmueller et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Estimators of the Human Effective Sex Ratio Detect Sex Biases on Different Timescales

(2010) Leslie S. Emery et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Inferences About the Distribution of Dominance Drawn From Yeast Gene Knockout Data

(2010) A. F. Agrawal et al.   GENETICS

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

Proportionally more deleterious genetic variation in European than in African populations

(2008) Kirk E. Lohmueller et al.   NATURE

Accelerated genetic drift on chromosome X during the human dispersal out of Africa

(2008) Alon Keinan et al.   NATURE GENETICS

Genome-Scale Proteomics Reveals Arabidopsis thaliana Gene Models and Proteome Dynamics

(2008) K. Baerenfaller et al.   SCIENCE

Sex-Biased Evolutionary Forces Shape Genomic Patterns of Human Diversity

(2008) Michael F. Hammer et al.   PLoS Genetics