Dissecting the regulation and function of ATP at the single-cell level

RGB-Color Intensiometric Indicators to Visualize Spatiotemporal Dynamics of ATP in Single Cells

(2018) Satoshi Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure

(2018) Bryce A. Mendelsohn et al.   PLOS BIOLOGY

Autonomous Metabolic Oscillations Robustly Gate the Early and Late Cell Cycle

(2017) Alexandros Papagiannakis et al.   MOLECULAR CELL

Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle

(2017) Eunyong Ahn et al.   Molecular Systems Biology

Mitochondrial diseases: the contribution of organelle stress responses to pathology

(2017) Anu Suomalainen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism

(2016) Joni Nikkanen et al.   Cell Metabolism

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling

(2015) Divya Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coenzyme Q10 as a therapy for mitochondrial disease

(2014) I.P. Hargreaves   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging

(2014) Hideyuki Yaginuma et al.   Scientific Reports

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

A Genetically Encoded FRET Lactate Sensor and Its Use To Detect the Warburg Effect in Single Cancer Cells

(2013) Alejandro San Martín et al.   PLoS One

Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio

(2013) Mathew Tantama et al.   Nature Communications

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Monogenic Mitochondrial Disorders

(2012) Werner J.H. Koopman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Luminescent proteins for high-speed single-cell and whole-body imaging

(2012) Kenta Saito et al.   Nature Communications

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation

(2010) Yuansong Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Connecting Variability in Global Transcription Rate to Mitochondrial Variability

(2010) Ricardo Pires das Neves et al.   PLOS BIOLOGY

A genetically encoded fluorescent reporter of ATP:ADP ratio

(2009) Jim Berg et al.   NATURE METHODS

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL