Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver

Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes

(2018) Dongyin Guan et al.   CELL

Integrated analysis of motif activity and gene expression changes of transcription factors

(2017) Jesper Grud Skat Madsen et al.   GENOME RESEARCH

Hair cortisol and adiposity in a population-based sample of 2,527 men and women aged 54 to 87 years

(2017) Sarah E. Jackson et al.   Obesity

Unraveling the Regulation of Hepatic Metabolism by Insulin

(2017) Paul M. Titchenell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome

(2017) Daniel Mauvoisin et al.   Cell Reports

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

(2017) Jonathan Aryeh Sobel et al.   PLOS BIOLOGY

High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss

(2017) Majken Siersbæk et al.   Scientific Reports

PPARα-dependent Insig2a overexpression inhibits SREBP-1c processing during fasting

(2017) Jae-Ho Lee et al.   Scientific Reports

SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation

(2016) Manuel Roqueta-Rivera et al.   Cell Metabolism

Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan

(2016) Valter D. Longo et al.   Cell Metabolism

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation

(2016) Sandip K. Bose et al.   ENDOCRINOLOGY

Circadian Clock Control of Liver Metabolic Functions

(2016) Hans Reinke et al.   GASTROENTEROLOGY

Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response

(2016) Ido Goldstein et al.   GENOME RESEARCH

Circadian rhythms of liver physiology and disease: experimental and clinical evidence

(2016) Yu Tahara et al.   Nature Reviews Gastroenterology & Hepatology

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

(2015) Rachel J. Perry et al.   CELL

Keeping circadian time with hormones

(2015) E. Challet   DIABETES OBESITY & METABOLISM

Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing

(2015) Diana A. Stavreva et al.   GENOME RESEARCH

60 YEARS OF NEUROENDOCRINOLOGY: Glucocorticoid dynamics: insights from mathematical, experimental and clinical studies

(2015) Francesca Spiga et al.   JOURNAL OF ENDOCRINOLOGY

Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver

(2015) Florian Atger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo

(2015) Paul M. Titchenell et al.   Nature Communications

FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis

(2015) Rachel J. Perry et al.   Nature Communications

FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization

(2015) InSug O-Sullivan et al.   Nature Communications

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

(2014) M. P. Sajan et al.   DIABETES

Minireview: New Molecular Mediators of Glucocorticoid Receptor Activity in Metabolic Tissues

(2014) Rucha Patel et al.   MOLECULAR ENDOCRINOLOGY

In-Vivo Quantitative Proteomics Reveals a Key Contribution of Post-Transcriptional Mechanisms to the Circadian Regulation of Liver Metabolism

(2014) Maria S. Robles et al.   PLoS Genetics

Fatty Acid–Regulated Transcription Factors in the Liver

(2013) Donald B. Jump et al.   Annual Review of Nutrition

Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver

(2013) Logan J Everett et al.   BMC GENOMICS

Reprogramming of the Circadian Clock by Nutritional Challenge

(2013) Kristin L. Eckel-Mahan et al.   CELL

The circadian epigenome: how metabolism talks to chromatin remodeling

(2013) Lorena Aguilar-Arnal et al.   CURRENT OPINION IN CELL BIOLOGY

C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements

(2013) Lars Grøntved et al.   EMBO JOURNAL

Circadian adaptations to meal timing: neuroendocrine mechanisms

(2013) Danica F. Patton et al.   Frontiers in Neuroscience

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Clocks, Metabolism, and the Epigenome

(2012) Dan Feng et al.   MOLECULAR CELL

An expansive human regulatory lexicon encoded in transcription factor footprints

(2012) Shane Neph et al.   NATURE

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Rapid genome-scale mapping of chromatin accessibility in tissue

(2012) Lars Grøntved et al.   Epigenetics & Chromatin

Genome-Wide RNA Polymerase II Profiles and RNA Accumulation Reveal Kinetics of Transcription and Associated Epigenetic Changes During Diurnal Cycles

(2012) Gwendal Le Martelot et al.   PLOS BIOLOGY

The Transcription Factor Encyclopedia

(2012) Dimas Yusuf et al.   GENOME BIOLOGY

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

(2011) Matthew J. Potthoff et al.   Cell Metabolism

FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis

(2011) S. Kir et al.   SCIENCE

Unbiased, Genome-Wide In Vivo Mapping of Transcriptional Regulatory Elements Reveals Sex Differences in Chromatin Structure Associated with Sex-Specific Liver Gene Expression

(2010) G. Ling et al.   MOLECULAR AND CELLULAR BIOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

FGF15/FGFR4 Integrates Growth Factor Signaling with Hepatic Bile Acid Metabolism and Insulin Action

(2009) Dong-Ju Shin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

(2009) Diana A. Stavreva et al.   NATURE CELL BIOLOGY

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation

(2008) Xiaocheng C. Dong et al.   Cell Metabolism