Article
Multidisciplinary Sciences
Kazufumi Sakamoto, Yoshitsune Hondo, Naoki Takahashi, Yuhei Tanaka, Rikuto Sekine, Kenji Shimoda, Haruki Watanabe, Kenji Yasuda
Summary: The study found that synchronized beating intervals of cardiomyocyte clusters were longer than those of isolated single cells, contradicting conventional regulations. This suggests that emergent slower synchronous beating occurred as a community effect of spontaneously beating cells within homogeneous cardiomyocyte clusters.
SCIENTIFIC REPORTS
(2021)
Article
Materials Science, Multidisciplinary
Yuchan Huang, Tang Zhu, Zijuan Zhu, Huixin Yuan, Liru Tan, Pingping Yao, Yongna Qiao, Caizhen Zhu, Jian Xu
Summary: Researchers have developed a multifunctional hydrogel with self-adhesive, highly stretchable, and conductive properties by introducing polydopamine and carbon fiber into polyacrylamide hydrogel. This hydrogel can be directly adhered to the skin as a strain sensor to monitor human body motion.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Engineering, Environmental
Xiangdong Wang, Xiaoyu Wang, Menghan Pi, Rong Ran
Summary: This paper presents a new method to balance the electrical conductivity and mechanical strength of materials by embedding HEC in hydrogel, resulting in an organic hydrogel with high strength and high conductivity. Additionally, temperature-sensitive particles were added to prepare temperature-sensitive conductive fibers for multiple sensors in the future.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Biomedical
Feng Zhang, Kaiyun Qu, Xiaopei Li, Chaoming Liu, Lazarus S. Ortiz, Kaihong Wu, Xiaowei Wang, Ningping Huang
Summary: A gelatin hydrogel crosslinked by genipin was developed for cell culture scaffolds, promoting synchronous beating of neonatal rat cardiomyocytes and maturation through electrical stimulation. This system shows potential for physiological function maturation of engineered cardiac tissues, with applications in cardiac tissue engineering and drug screening.
BIO-DESIGN AND MANUFACTURING
(2021)
Article
Engineering, Electrical & Electronic
Yongyi Zhao, Yunsik Ohm, Jiahe Liao, Yichi Luo, Huai-Yu Cheng, Phillip Won, Peter Roberts, Manuel Reis Carneiro, Mohammad F. F. Islam, Jung Hyun Ahn, Lynn M. M. Walker, Carmel Majidi
Summary: Self-healing hydrogels have the potential to recover from physical damage caused by extreme strain, pressure, or tearing. However, their low electrical conductivity limits their application in stretchable and mechanically robust circuits. In this study, we developed an organogel composite with high electrical conductivity, low stiffness, and high stretchability by embedding silver microflakes and gallium-based liquid metal microdroplets in a poly(vinyl alcohol)-sodium borate matrix. The composite also exhibited spontaneous mechanical and electrical self-healing. Furthermore, we addressed the rapid drying issue of hydrogel materials by using an organic solvent, which maintained the properties of the composite for over 24 hours in an ambient environment. We demonstrated the potential applications of the self-healing organogel composite in soft robotics, soft circuits, and reconfigurable bioelectrodes.
NATURE ELECTRONICS
(2023)
Article
Nanoscience & Nanotechnology
Changhua Yang, Yanan Wu, Min Nie, Qi Wang, Yuansen Liu
Summary: In this study, interlocking interfaces were successfully constructed in a polyurethane conductive composite by introducing zinc oxide nanowires with brush-like carbon fibers, greatly improving the mechanical strength and conductive stability of the material. High mechanical strength and stable conductivity were demonstrated in the composite, and the novel stretchable conductor showed potential applications in thermal therapy units and flexible circuits.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Environmental
Lingyu Sun, Xiyu Zhu, Xiaoxuan Zhang, Guopu Chen, Feika Bian, Junxia Wang, Qing Zhou, Dongjin Wang, Yuanjin Zhao
Summary: A novel cardiac patch integrating conductive microneedles and iPSC-derived CMs is proposed for MI treatment, featuring anisotropic structure and conductive elements. This patch shows potential as an ideal therapy strategy for cardiac diseases.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Physical
Francisco J. Garcia-Mateos, Juana M. Rosas, Ramiro Ruiz-Rosas, Jose Rodriguez-Mirasol, Tomas Cordero
Summary: Functional carbon fibers with high porosity and surface area can be prepared by thermal treatment and doping with phosphoric acid. The presence of phosphorus preserves the porosity of the fibers at high temperature and allows for the development of electrical conductivity.
Article
Multidisciplinary Sciences
Chaojie Yu, Mingyue Shi, Shaoshuai He, Mengmeng Yao, Hong Sun, Zhiwei Yue, Yuwei Qiu, Baijun Liu, Lei Liang, Zhongming Zhao, Fanglian Yao, Hong Zhang, Junjie Li
Summary: In this study, the authors report a functionalized polyaniline-based chronological adhesive hydrogel patch that integrates diagnostic and therapeutic functions through mechanophysiological monitoring and electrocoupling therapy for the treatment of myocardial infarction.
NATURE COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Akhmad Irhas Robby, Seul Gi Kim, Hyeong Jun Jo, Gibaek Lee, Hyoung Sin Lee, Kang Dae Lee, Ji Hyun Ryu, Sung Young Park
Summary: The tumor microenvironment-responsive wireless strain-pressure hydrogel sensor is designed based on pH-induced controllable nanoparticles for cancer detection, with the ability to distinguish between cancer and normal cells effectively; By applying strain and pressure, the hydrogel demonstrates higher sensitivity and selectivity when interacting with cancer cells compared to normal cells, showing potential for sensitive and selective tumor detection in point-of-care diagnostic applications.
APPLIED MATERIALS TODAY
(2021)
Article
Materials Science, Multidisciplinary
Jiuming Xiong, Weijun Wu, Yufang Hu, Zhiyong Guo, Sui Wang
Summary: This study developed a conductive wood-based hydrogel (CWH) by utilizing conductive wood as a scaffold and incorporating a precursor solution. The CWH demonstrated anisotropic mechanical and electrical properties, stable strain sensitivity, and resistance to expansion in humid environments. It also showed promising potential for humidity-driven power generation and breath detection.
APPLIED MATERIALS TODAY
(2023)
Article
Biochemistry & Molecular Biology
Zhicong Lin, Donghao Fan, Guojiao Li, Liming He, Xianyan Qin, Bin Zhao, Qin Wang, Wenlang Liang
Summary: This study developed a hydrogel with tissue adhesivity, conductivity, and antibacterial function, which showed promising results in promoting diabetic wound healing.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Engineering, Biomedical
Zhanrong Jia, Xuanhan Lv, Yue Hou, Kefeng Wang, Fuzeng Ren, Dingguo Xu, Qun Wang, Kelong Fan, Chaoming Xie, Xiong Lu
Summary: This study presents a mussel-inspired nanozyme-catalyzed adhesive hydrogel with multiple functions, including adhesiveness, antibacterial activity, and implantable bioelectrode capabilities. It shows great potential for various applications in the medical field.
BIOACTIVE MATERIALS
(2021)
Article
Construction & Building Technology
H. N. Yoon, Daeik Jang, Taegeon Kil, H. K. Lee
Summary: This study examined the changes in electrical properties of cement pastes incorporating CNT and CF exposed to various deterioration factors. The electrical resistivity of the samples increased with exposure time, and a rapid change in resistivity due to the polarization effect was observed. However, the incorporation of micro-sized CF mitigated the increase in resistivity caused by deterioration, improving electrical stability in different environments. Exposure to deterioration conditions caused changes in physicochemical structures and resulted in changes in electrical resistivity.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Engineering, Multidisciplinary
Di Wang, Jin Zhang, Chonghui Fan, Jian Xing, Anfang Wei, Wenzheng Xu, Quan Feng, Qufu Wei
Summary: A novel fiber reinforced organohydrogel with excellent mechanical properties, ionic conductivity, and low-temperature tolerance has been developed for practical applications. It also shows promising potential as a wearable strain sensor with high sensitivity, stability, and repeatability.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Cell Biology
RongLing He, XiangNing Yuan, Xin Lv, QingXiang Liu, LiJian Tao, Jie Meng
Summary: The study found that Cav-1 levels were significantly reduced in the lungs of silicosis patients and mice, and absence of Cav-1 exacerbated lung damage in silicosis models. Cav-1 plays a protective role in silica-induced lung injury by inhibiting inflammatory responses and oxidative stress.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2022)
Article
Engineering, Multidisciplinary
Chao Liu, Hui Wang, Yu Huang, Youmin Rong, Jie Meng, Gen Li, Guojun Zhang
Summary: A novel intelligent mobile welding robot with adaptive seam tracking ability has been developed, which can navigate autonomously to different stations for welding operations. The robot utilizes a multi-layer sensing strategy and a composite sensor system to accurately detect and track the welding seam, improving the welding quality and efficiency.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Sidian Zhang, Xue Zhang, Jie Meng, Ling Lu, Shanda Du, Haiyan Xu, Sizhu Wu
Summary: This study combines experimental characterization and molecular simulation to investigate the solubilization of myricetin by solid dispersion. The effectiveness of poly(vinyl pyrrolidone) > hypromellose > poly(ethylene glycol) as polymer excipients is confirmed through analysis of dispersibility and hydrogen-bond interaction. The reliability of simulation and micromechanism analysis is further confirmed by dissolution, cell viability, and ROS-level detection.
Article
Chemistry, Applied
Tian Wang, Boya Hao, Shilin Xu, Jie Meng, Tao Wen, Jian Liu, Haiyan Xu
Summary: This study established a universal strategy for effective RNA interference in different types of leukemia cells by using PS as an siRNA carrier and DL to promote lysosomal escape. The complex of PS and siRNA could be internalized by leukemia cells and escape from lysosomes with the aid of DL, resulting in effective RNAi against key genes.
CARBOHYDRATE POLYMERS
(2022)
Article
Nanoscience & Nanotechnology
Tao Wang, Xue Zhang, Mengfan Jia, Aiyun Yang, Jian Liu, Tao Wen, Jie Meng, Haiyan Xu
Summary: This study investigates the differentiation-induction effects of lab-developed hydrophilic nanocrystals of As4S4 (ee-As4S4) on acute myeloid leukemia (AML) cells. The results show that ee-As4S4 induces effective and multiple-lineage differentiation and apoptosis of AML cells in mouse models and cell lines. The inhibition of histone deacetylase activity plays an important role in the differentiation-induction effects. Furthermore, ee-As4S4 improves the survival of AML mice without causing acute or chronic toxicity in healthy mice, suggesting its promising potential as a novel inductive agent in differentiation therapy of AML.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Engineering, Mechanical
Liquan Jiang, Shuting Wang, Yuanlong Xie, Sheng Quan Xie, Shiqi Zheng, Jie Meng
Summary: This study introduces a novel adaptive fractional robust finite time controller, which achieves the required control accuracy and stability under serious time-varying perturbations by designing constrained prediction and sliding mode mechanisms.
MECHANISM AND MACHINE THEORY
(2022)
Article
Cell Biology
Xiaohua Liao, Xin Lv, Yan Zhang, Yuanyuan Han, Jiajia Li, Jianhua Zeng, Damu Tang, Jie Meng, Xiangning Yuan, Zhangzhe Peng, Lijian Tao, Yanyun Xie
Summary: The study found that fluorofenidone (AKF-PD) can attenuate renal fibrosis by protecting mitochondria. The underlying mechanism involves sustaining mitochondrial energy metabolism, improving mitochondrial biogenesis, and reducing mitochondrial oxidative stress.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2022)
Article
Nanoscience & Nanotechnology
Aiyun Yang, Tao Wen, Boya Hao, Yiling Meng, Xue Zhang, Tian Wang, Jie Meng, Jian Liu, Jianhua Wang, Haiyan Xu
Summary: In this study, nanorods composed of ultrasmall platinum nanoparticles were synthesized and their distribution and toxic effects in mice were investigated. The results showed that the nanorods mainly accumulated in the liver and spleen without significant toxic effects on organ function.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Nanoscience & Nanotechnology
Xue Zhang, Fei Kong, Tian Wang, Xin Huang, Wanqing Li, Meichen Zhang, Tao Wen, Jian Liu, Yu Zhang, Jie Meng, Haiyan Xu
Summary: In this study, the interaction between three types of iron oxide nanoparticles (IONPs) with vascular endothelial cells was investigated. It was found that certain nanoparticles can induce cell growth inhibition and ferroptosis, and the surface coating and core chemistry of the nanoparticles play a role in these effects.
Article
Pharmacology & Pharmacy
Jiajia Li, Yupeng Jiang, Qin Dai, Yue Yu, Xin Lv, Yan Zhang, Xiaohua Liao, Liyun Ao, Gaoyun Hu, Jie Meng, Zhangzhe Peng, Lijian Tao, Yanyun Xie
Summary: In this study, the protective effect of Mefunidone on ischemia-reperfusion injury-induced acute kidney injury was investigated. The results showed that Mefunidone can protect the kidney by relieving kidney tubular injury, suppressing oxidative stress, and inhibiting cell apoptosis. Furthermore, Mefunidone reduced mitochondrial damage and protected mitochondrial function.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Engineering, Biomedical
Jie Meng, Bo Xiao, Fengxin Wu, Lihong Sun, Bo Li, Wen Guo, Xuechun Hu, Xuegai Xu, Tao Wen, Jian Liu, Haiyan Xu
Summary: The integration of carbon fibers and coaxial fibrous mesh in the scaffold can enhance cardiomyocyte maturation and angiogenesis, promoting myocardial regeneration and functional recovery, thus rescuing heart dysfunction.
MATERIALS TODAY BIO
(2022)
Article
Business
Ying Feng, Jie Meng
Summary: This study examines the impact of physical and psychological distance on individuals' perception of connectedness with the servicescape and their perception of value. It also explores how consumers' techno-psychological differences and interaction modes influence this distance-closeness relationship. Using a quasi-experimental design in three service scenarios, the researchers find that contactless technology can effectively change high self-efficiency customers' perception of closeness to the servicescape and their evaluation of the service in distancing settings. The findings have practical implications for different types of consumers in service encounters during or after the COVID-19 pandemic.
JOURNAL OF INTERACTIVE MARKETING
(2023)
Article
Humanities, Multidisciplinary
Zirui Wang, Jie Meng
Summary: This study investigates the impact of digitalisation on the attractiveness and value perception of cultural heritage displays among younger generations, and proposes an integrated model to reveal the associations between relevant variables.
MUSEUM MANAGEMENT AND CURATORSHIP
(2023)
Article
Nanoscience & Nanotechnology
Shilin Xu, Meichen Zhang, Xiaocui Fang, Xuechun Hu, Haiyan Xing, Yanlian Yang, Jie Meng, Tao Wen, Jian Liu, Jianxiang Wang, Chen Wang, Haiyan Xu
Summary: A novel therapeutic strategy for acute myeloid leukemia (AML) was studied, which involved the fabrication of nanomicelles loaded with a CD123 antagonistic peptide. In vitro and in vivo experiments demonstrated that the nanomicelles, referred to as mPO-6, specifically bound to CD123+ AML cells and effectively inhibited cell viability. Intravenous administration of mPO-6 reduced AML cell infiltration and prolonged the survival of AML mice. Further investigation revealed that mPO-6 interfered with the CD123/IL-3 axis by regulating the activation of STAT5, PI3K/AKT, and NF-Kappa B signaling pathways related to cell proliferation or apoptosis at the mRNA and protein levels.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Retraction
Cell Biology
Jingjing Liu, Liming Cao, Jie Meng, Yuanyuan Li, Pengbo Deng, Pinhua Pan, Chengping Hu, Huaping Yang
