Structural basis for dimerization of the death effector domain of the F122A mutant of Caspase-8

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

(2016) Michelle A. Hughes et al.   MOLECULAR CELL

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex

(2016) Tian-Min Fu et al.   MOLECULAR CELL

Crystal structure of the death effector domains of caspase-8

(2015) Chen Shen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers

(2014) Jason M. Brouwer et al.   MOLECULAR CELL

Crystal Structure of a Complex of NOD1 CARD and Ubiquitin

(2014) Aaron M. Ver Heul et al.   PLoS One

Functions of caspase 8: The identified and the mysterious

(2014) Guy S. Salvesen et al.   SEMINARS IN IMMUNOLOGY

Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions

(2014) Clarissa Eibl et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis

(2013) Peter E. Czabotar et al.   CELL

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

(2012) Laura S. Dickens et al.   MOLECULAR CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

(2011) Andrew Oberst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aggregation of  -crystallins associated with human cataracts via domain swapping at the C-terminal  -strands

(2011) P. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The death-fold superfamily of homotypic interaction motifs

(2011) Kristof Kersse et al.   TRENDS IN BIOCHEMICAL SCIENCES

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular cell death platforms and assemblies

(2010) Peter D Mace et al.   CURRENT OPINION IN CELL BIOLOGY

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

(2010) Andrew Oberst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

(2010) Liwei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein acrobatics in pairs—dimerization via domain swapping

(2009) Angela M Gronenborn   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

(2009) Fiona L. Scott et al.   NATURE

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

(2009) Lorraine A. O’ Reilly et al.   NATURE

Monomer/Dimer Transition of the Caspase-Recruitment Domain of Human Nod1†,‡

(2008) Thiagarajan Srimathi et al.   BIOCHEMISTRY

Identification of a Critical Tyrosine Residue in Caspase 8 That Promotes Cell Migration

(2008) Simone Barbero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

(2008) Masayuki Yamasaki et al.   NATURE

FLIP and the death effector domain family

(2008) J W Yu et al.   ONCOGENE