Reversible senescence of human colon cancer cells after blockage of mitosis/cytokinesis caused by the CNF1 cyclomodulin from Escherichia coli

New therapeutics from Nature: The odd case of the bacterial cytotoxic necrotizing factor 1

(2018) Zaira Maroccia et al.   BIOMEDICINE & PHARMACOTHERAPY

Cytotoxic necrotizing factor 1 promotes prostate cancer progression through activating the Cdc42-PAK1 axis

(2017) Yaxiu Guo et al.   JOURNAL OF PATHOLOGY

A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death

(2017) Svitlana Vdovikova et al.   Frontiers in Cellular and Infection Microbiology

Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections

(2017) Rachid A. El-Aouar Filho et al.   Frontiers in Cellular and Infection Microbiology

Naturally Occurring IgG Antibodies Provide Innate Protection against Vibrio cholerae Bacteremia by Recognition of the Outer Membrane Protein U

(2016) Kyaw Min Aung et al.   Journal of Innate Immunity

Antibodies against Hemolysin and Cytotoxic Necrotizing Factor Type 1 (CNF1) Reduce Bladder Inflammation in a Mouse Model of Urinary Tract Infection with Toxigenic Uropathogenic Escherichia coli

(2015) Mark A. Smith et al.   INFECTION AND IMMUNITY

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells

(2015) C Leikam et al.   Cell Death & Disease

Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence

(2015) Grazyna Mosieniak et al.   NEOPLASIA

Outer Membrane Vesicle-Mediated Export of Processed PrtV Protease from Vibrio cholerae

(2015) Pramod K. Rompikuntal et al.   PLoS One

The bacterial protein toxin, cytotoxic necrotizing factor 1 (CNF1) provides long-term survival in a murine glioma model

(2014) Eleonora Vannini et al.   BMC CANCER

Failure of cell cleavage induces senescence in tetraploid primary cells

(2014) Andreas Panopoulos et al.   MOLECULAR BIOLOGY OF THE CELL

Colon cancer-associated B2Escherichia colicolonize gut mucosa and promote cell proliferation

(2014) Jennifer Raisch   WORLD JOURNAL OF GASTROENTEROLOGY

Lu/BCAM Adhesion Glycoprotein Is a Receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

(2014) Marianne Piteau et al.   PLoS Pathogens

Hijacking of Rho GTPases during bacterial infection

(2013) Emmanuel Lemichez et al.   EXPERIMENTAL CELL RESEARCH

High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

(2013) Emmanuel Buc et al.   PLoS One

Activation of RhoA,B,C by Yersinia Cytotoxic Necrotizing Factor (CNFy) Induces Apoptosis in LNCaP Prostate Cancer Cells

(2013) Anke Augspach et al.   Toxins

Cellular senescence and cancer chemotherapy resistance

(2012) Ryan R. Gordon et al.   DRUG RESISTANCE UPDATES

Polyploidy road to therapy-induced cellular senescence and escape

(2012) Qin Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Putative virulence genes in Moritella viscosa: Activity during in vitro inoculation and in vivo infection

(2011) Hege Smith Tunsjø et al.   MICROBIAL PATHOGENESIS

Bacterial protein toxins that modify host regulatory GTPases

(2011) Klaus Aktories   NATURE REVIEWS MICROBIOLOGY

Cyclomodulins in Urosepsis Strains of Escherichia coli

(2010) D. Dubois et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Therapy-Induced Senescence in Cancer

(2010) Jonathan A. Ewald et al.   JNCI-Journal of the National Cancer Institute

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

(2010) M. Fenech et al.   MUTAGENESIS

Cytotoxic Necrotizing Factors (CNFs)−A Growing Toxin Family

(2010) Zeynep Knust et al.   Toxins

Endoreplication: polyploidy with purpose

(2009) H. O. Lee et al.   GENES & DEVELOPMENT

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

(2008) Pierre-Emmanuel Puig et al.   CELL BIOLOGY INTERNATIONAL

Hemolysin of Uropathogenic Escherichia coli Evokes Extensive Shedding of the Uroepithelium and Hemorrhage in Bladder Tissue within the First 24 Hours after Intraurethral Inoculation of Mice

(2008) Y. C. Smith et al.   INFECTION AND IMMUNITY

Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells

(2008) Malgorzata A. Sliwinska et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Rho-activating CNF1 toxin from pathogenic E. coli: A risk factor for human cancer development?

(2008) Sara Travaglione et al.   Infectious Agents and Cancer