Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment

Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease

(2018) Jose D. Pagan et al.   CELL

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement

(2018) Spencer A. Freeman et al.   CELL

Fcγ Receptor Function and the Design of Vaccination Strategies

(2017) Stylianos Bournazos et al.   IMMUNITY

Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases

(2017) Hiroshi Nishi et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential antibody glycosylation in autoimmunity: sweet biomarker or modulator of disease activity?

(2017) Michaela Seeling et al.   Nature Reviews Rheumatology

Effects of anchor structure and glycosylation of Fcγ receptor III on ligand binding affinity

(2016) Ning Jiang et al.   MOLECULAR BIOLOGY OF THE CELL

Leukocyte integrin αLβ2headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops

(2016) Mehmet Sen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monocyte Recruitment by HLA IgG-Activated Endothelium: The Relationship Between IgG Subclass and FcγRIIa Polymorphisms

(2015) N. M. Valenzuela et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The many faces of Mac-1 in autoimmune disease

(2015) Florencia Rosetti et al.   IMMUNOLOGICAL REVIEWS

Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell

(2015) Yunfeng Chen et al.   Jove-Journal of Visualized Experiments

An internal ligand-bound, metastable state of a leukocyte integrin, αXβ2

(2014) Mehmet Sen et al.   JOURNAL OF CELL BIOLOGY

Fc Gamma Receptor Glycosylation Modulates the Binding of IgG Glycoforms: A Requirement for Stable Antibody Interactions

(2014) Jerrard M. Hayes et al.   JOURNAL OF PROTEOME RESEARCH

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

(2014) Caitlin Gillis et al.   Frontiers in Immunology

β2integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation

(2013) Nathan K. Yee et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Complement Receptor 3 Influences Toll-like Receptor 7/8-Dependent Inflammation

(2013) Joanne H. Reed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CD11b-integrin (ITGAM) and systemic lupus erythematosus

(2013) SC Fagerholm et al.   LUPUS

Role of Activating Fc γ R Gene Polymorphisms in Kawasaki Disease Susceptibility and Intravenous Immunoglobulin Response

(2012) Sadeep Shrestha et al.   Circulation-Cardiovascular Genetics

Human Lupus Serum Induces Neutrophil-Mediated Organ Damage in Mice That Is Enabled by Mac-1 Deficiency

(2012) F. Rosetti et al.   JOURNAL OF IMMUNOLOGY

The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer

(2012) Angela M. Bair et al.   MOLECULAR BIOLOGY OF THE CELL

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

(2012) Sapna Devi et al.   NATURE MEDICINE

Structural Basis for Fc RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes

(2011) P. A. Ramsland et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease

(2011) Chiea Chuen Khor et al.   NATURE GENETICS

Emerging mechanisms of neutrophil recruitment across endothelium

(2011) Marcie R. Williams et al.   TRENDS IN IMMUNOLOGY

Regulation of human neutrophil Fcγ receptor IIa by C5a receptor promotes inflammatory arthritis in mice

(2010) Naotake Tsuboi et al.   ARTHRITIS AND RHEUMATISM

Indirect Inhibition of Toll-like Receptor and Type I Interferon Responses by ITAM-Coupled Receptors and Integrins

(2010) Lu Wang et al.   IMMUNITY

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

(2010) Chaofeng Han et al.   NATURE IMMUNOLOGY

Association of Fc RIIa (CD32a) with Lipid Rafts Regulates Ligand Binding Activity

(2009) S. Bournazos et al.   JOURNAL OF IMMUNOLOGY

Sphingosine 1-Phosphate Enhances Fc  Receptor-Mediated Neutrophil Activation and Recruitment under Flow Conditions

(2009) O. Florey et al.   JOURNAL OF IMMUNOLOGY

Cross-regulation of signaling by ITAM-associated receptors

(2009) Lionel B Ivashkiv   NATURE IMMUNOLOGY

Neutrophil-selective CD18 silencing using RNA interference in vivo

(2008) X. Cullere et al.   BLOOD

Human Neutrophil Fcγ Receptors Initiate and Play Specialized Nonredundant Roles in Antibody-Mediated Inflammatory Diseases

(2008) Naotake Tsuboi et al.   IMMUNITY

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

(2008) Swapan K Nath et al.   NATURE GENETICS

Making autoantibodies safe

(2008) C. N. Scanlan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

(2008) R. M. Anthony et al.   SCIENCE