Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Biomarker clusters are differentially associated with longitudinal cognitive decline in late midlife

(2016) Annie M. Racine et al.   BRAIN

A multivariate nonlinear mixed effects model for longitudinal image analysis: Application to amyloid imaging

(2016) Murat Bilgel et al.   NEUROIMAGE

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis

(2015) Jonathan D Rohrer et al.   LANCET NEUROLOGY

C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis

(2015) Jonathan D Rohrer et al.   LANCET NEUROLOGY

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

(2014) Michael D. Gallagher et al.   ACTA NEUROPATHOLOGICA

Estimating long-term multivariate progression from short-term data

(2014) Michael C. Donohue et al.   Alzheimers & Dementia

Biological heterogeneity in ADNI amnestic mild cognitive impairment

(2014) Jasmine Nettiksimmons et al.   Alzheimers & Dementia

A data-driven model of biomarker changes in sporadic Alzheimer's disease

(2014) Alexandra L. Young et al.   BRAIN

Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

(2014) Marka van Blitterswijk et al.   Molecular Neurodegeneration

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

(2014) Marka van Blitterswijk et al.   NEUROBIOLOGY OF AGING

Anatomical heterogeneity of Alzheimer disease: Based on cortical thickness on MRIs

(2014) Y. Noh et al.   NEUROLOGY

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

Brain  -amyloid load approaches a plateau

(2013) C. R. Jack et al.   NEUROLOGY

Understanding predictive information criteria for Bayesian models

(2013) Andrew Gelman et al.   STATISTICS AND COMPUTING

Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

(2013) Benjamin Lam et al.   Alzheimers Research & Therapy

Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features

(2012) C. J. Mahoney et al.   BRAIN

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics

(2012) J. L. Whitwell et al.   BRAIN

Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study

(2012) Jennifer L Whitwell et al.   LANCET NEUROLOGY

An event-based model for disease progression and its application in familial Alzheimer's disease and Huntington's disease

(2012) Hubert M. Fonteijn et al.   NEUROIMAGE

A computational neurodegenerative disease progression score: Method and results with the Alzheimer's disease neuroimaging initiative cohort

(2012) Bruno M. Jedynak et al.   NEUROIMAGE

A Network Diffusion Model of Disease Progression in Dementia

(2012) Ashish Raj et al.   NEURON

Predicting Regional Neurodegeneration from the Healthy Brain Functional Connectome

(2012) Juan Zhou et al.   NEURON

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

(2011) J. D. Rohrer et al.   BRAIN

Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study

(2011) Melissa E Murray et al.   LANCET NEUROLOGY

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Subtypes based on cerebrospinal fluid and magnetic resonance imaging markers in normal elderly predict cognitive decline

(2010) J. Nettiksimmons et al.   NEUROBIOLOGY OF AGING

TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia

(2010) J. D. Rohrer et al.   NEUROLOGY

Does TDP-43 type confer a distinct pattern of atrophy in frontotemporal lobar degeneration?

(2010) J. L. Whitwell et al.   NEUROLOGY

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: a cluster analysis study

(2009) J. L. Whitwell et al.   BRAIN

Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M MAPT mutations

(2009) J. L. Whitwell et al.   NEUROLOGY