Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability
出版年份 2018 全文链接
标题
Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability
作者
关键词
-
出版物
Frontiers in Cellular Neuroscience
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-10-09
DOI
10.3389/fncel.2018.00338
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Recent developments with tau-based drug discovery
- (2018) Khalid Iqbal et al. Expert Opinion on Drug Discovery
- Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer’s Disease
- (2018) Yan Zhou et al. Frontiers in Aging Neuroscience
- Expression of Alzheimer-Like Pathological Human Tau Induces a Behavioral Motor and Olfactory Learning Deficit in Drosophila melanogaster
- (2018) Cindy Beharry et al. JOURNAL OF ALZHEIMERS DISEASE
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- What is the evidence that tau pathology spreads through prion-like propagation?
- (2017) Amrit Mudher et al. Acta Neuropathologica Communications
- Molecular mechanism of prion-like tau-induced neurodegeneration
- (2016) Alejandra D. Alonso et al. Alzheimers & Dementia
- Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss
- (2016) J. Di et al. Scientific Reports
- Nuclear Magnetic Resonance Spectroscopy Characterization of Interaction of Tau with DNA and Its Regulation by Phosphorylation
- (2015) Haoling Qi et al. BIOCHEMISTRY
- Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles
- (2015) Gerhard Multhaup et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3
- (2015) Pritam Ganguly et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Tau co-organizes dynamic microtubule and actin networks
- (2015) Auréliane Elie et al. Scientific Reports
- Tau promotes neurodegeneration through global chromatin relaxation
- (2014) Bess Frost et al. NATURE NEUROSCIENCE
- Tau-induced neurodegeneration: mechanisms and targets
- (2014) Cindy Beharry et al. Neuroscience Bulletin
- Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
- (2014) Scott J. Webster et al. Frontiers in Genetics
- The microtubule-associated tau protein has intrinsic acetyltransferase activity
- (2013) Todd J Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Positive and negative feedback loops in the p53 and mRNA 3′ processing pathways
- (2013) Emral Devany et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elevated Levels of Soluble Total and Hyperphosphorylated Tau Result in Early Behavioral Deficits and Distinct Changes in Brain Pathology in a New Tau Transgenic Mouse Model
- (2012) S. Flunkert et al. Neurodegenerative Diseases
- Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
- (2011) A. Sydow et al. JOURNAL OF NEUROSCIENCE
- Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease
- (2011) E. D. Roberson et al. JOURNAL OF NEUROSCIENCE
- Structural Impact of Proline-Directed Pseudophosphorylation at AT8, AT100, and PHF1 Epitopes on 441-Residue Tau
- (2011) Stefan Bibow et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
- (2011) Cristian A Lasagna-Reeves et al. Molecular Neurodegeneration
- Nuclear deadenylation/polyadenylation factors regulate 3′ processing in response to DNA damage
- (2010) Murat A Cevher et al. EMBO JOURNAL
- Phosphorylation of Tau at Thr212, Thr231, and Ser262Combined Causes Neurodegeneration
- (2010) Alejandra D. Alonso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Tau, a Key Player in Neuronal DNA Protection
- (2010) Audrey Sultan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New evidences on Tau–DNA interactions and relevance to neurodegeneration
- (2010) Vasudevaraju Padmaraju et al. NEUROCHEMISTRY INTERNATIONAL
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- Familial FTDP-17 Missense Mutations Inhibit Microtubule Assembly-promoting Activity of Tau by Increasing Phosphorylation at Ser202in Vitro
- (2009) Dong Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation
- (2009) M. Hundelt et al. NEUROBIOLOGY OF AGING
- Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease
- (2008) Siddhartha Mondragón-Rodríguez et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
- (2008) A. Gómez-Ramos et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation
- (2008) Yan Wei et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started