Article
Radiology, Nuclear Medicine & Medical Imaging
Salim A. Si-Mohamed, Sara Boccalini, Hugo Lacombe, Adja Diaw, Mohammad Varasteh, Pierre-Antoine Rodesch, Riham Dessouky, Marjorie Villien, Valerie Tatard-Leitman, Thomas Bochaton, Philippe Coulon, Yoad Yagil, Elias Lahoud, Klaus Erhard, Benjamin Riche, Eric Bonnefoy, Gilles Rioufol, Gerard Finet, Cyrille Bergerot, Loic Boussel, Joel Greffier, Philippe C. Douek
Summary: The study compared the quality of coronary CT angiography (CCTA) scans obtained with a photon-counting CT (PCCT) system and an energy-integrating dual-layer CT (DLCT) system. The results showed that PCCT provided improved image quality and diagnostic confidence compared to DLCT.
Review
Medicine, Research & Experimental
Steven D. Curry, Dallin N. Christensen, Pooja M. Varman, Kimberly A. Harp, Dwight T. Jones
Summary: This study evaluated the impact of CTA results on the diagnosis and treatment of pediatric oropharyngeal trauma. The results showed that CTA rarely resulted in changes in clinical management and did not improve outcomes, thus not supporting the routine use of CTA in screening pediatric oropharyngeal trauma.
Article
Surgery
Chun-Lin Su, Chung-Chen Hsu, Chien-Hung Liao, Chi-Hsun Hsieh, Chi-Tung Cheng, Chih-Yuan Fu
Summary: A prediction model and simplified scoring system for vascular injuries in patients with lower extremity open fractures were developed. Three clinical variables (hard or soft vascular signs, segmental fractures, and degloving soft-tissue injury) were identified for assessing the risk of vascular injuries. The model showed good performance in prediction and diagnosis, and can guide the subsequent management decisions for patients with lower extremity open fractures.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andres Rodriguez, Luis Nunez, Roy Riascos
Summary: Vascular injuries in head and neck trauma are critical emergencies that require prompt and accurate diagnosis to prevent severe consequences. Clinical suspicion and early imaging evaluation are crucial for timely management and reducing the risk of stroke and death. While CTA remains the leading imaging technique and DSA is still considered the gold standard, newer techniques can assist in identifying uncertain findings, providing added value in follow-up, and guiding treatment decisions.
RADIOLOGIC CLINICS OF NORTH AMERICA
(2023)
Article
Medical Informatics
Andrew Lin, Nipun Manral, Priscilla McElhinney, Aditya Killekar, Hidenari Matsumoto, Jacek Kwiecinski, Konrad Pieszko, Aryabod Razipour, Kajetan Grodecki, Caroline Park, Yuka Otaki, Mhairi Doris, Alan C. Kwan, Donghee Han, Keiichiro Kuronuma, Guadalupe Flores Tomasino, Evangelos Tzolos, Aakash Shanbhag, Markus Goeller, Mohamed Marwan, Heidi Gransar, Balaji K. Tamarappoo, Sebastien Cadet, Stephan Achenbach, Stephen J. Nicholls, Dennis T. Wong, Daniel S. Berman, Marc Dweck, David E. Newby, Michelle C. Williams, Piotr J. Slomka, Damini Dey
Summary: This study developed and validated a deep learning system for quantifying plaque volume and stenosis severity from coronary CT angiography (CCTA). The deep learning system showed excellent agreement with expert readers and intravascular ultrasound measurements, and had prognostic value for future myocardial infarction.
LANCET DIGITAL HEALTH
(2022)
Article
Surgery
Leigh Ann O'Banion, Rachel Dirks, Emaad Farooqui, Nallely Saldana-Ruiz, William J. Yoon, Cara Pozolo, Charles Fox, Alexis Crally, Sammy Siada, Mark R. Nehler, Benjamin S. Brooke, Julie L. Beckstrom, Sharon Kiang, Hans K. Boggs, Venita Chandra, Vy T. Ho, Wei Zhou, Ashton Lee, Nina Bowens, Yan Cho, Karen Woo, Jesus Ulloa, Gregory A. Magee
Summary: The study introduced a simplified scoring system (POPSAVEIT) for preoperative risk stratification of traumatic popliteal vascular injuries. The scoring system, based on multivariate analysis, independently assessed amputation risk in these patients and demonstrated good validation in the testing group.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Dentistry, Oral Surgery & Medicine
William Lane, Branden Brar, Pushkar Mehra
Summary: The study aimed to determine the incidence of blunt carotid injury (BCAI) in patients with isolated mandible fractures and assess the utility of computed tomographic angiography (CTA) screening for BCAI. Results showed a very low incidence of BCAI in isolated mandible fractures, questioning the inclusion of this population as an independent risk factor for BCAI. Therefore, routine screening with CTA is not recommended for isolated mandible fracture patients.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nicholas S. Burris, Zhangxing Bian, Jeffrey Dominic, Jianyang Zhong, Ignas B. Houben, Theodorus M. J. van Bakel, Himanshu J. Patel, Brian D. Ross, Gary E. Christensen, Charles R. Hatt
Summary: This study validated a CT-based technique for quantifying three-dimensional growth in patients with thoracic aortic aneurysms. The technique, called vascular deformation mapping, was found to provide reliable and comprehensive assessment of aortic growth and growth patterns. It detected growth that was not detected by diameter measurements.
Article
Radiology, Nuclear Medicine & Medical Imaging
Muhammad Naeem, Mark J. Hoegger, Frank W. Petraglia, David H. Ballard, Maria Zulfiqar, Michael N. Patlas, Constantine Raptis, Vincent M. Mellnick
Summary: Penetrating abdominopelvic trauma presents diagnostic challenges for radiologists due to its complexity and subtle imaging findings. Contrast-enhanced CT is the preferred modality for evaluating these injuries, providing good sensitivity and specificity. Familiarity with the projectile kinetics and the use of CT trajectography are important skills for radiologists in diagnosing both overt and subtle injuries.
Article
Radiology, Nuclear Medicine & Medical Imaging
Chiara Lauri, Giuseppe Campagna, Francesco Aloisi, Alessandro Posa, Roberto Iezzi, Pasqualino Sirignano, Maurizio Taurino, Alberto Signore
Summary: This study compared the use of Tc-99m-HMPAO white blood cell scintigraphy, [F-18]FDG PET/CT, and CTA in patients with suspected abdominal vascular graft or endograft infection. The results showed that [F-18]FDG PET/CT had high sensitivity and negative predictive value, while Tc-99m-WBC SPECT/CT had high specificity and positive predictive value. Therefore, [F-18]FDG PET/CT should be prioritized in suspected infections, but positive results should be confirmed with Tc-99m-WBC scintigraphy.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Emergency Medicine
Alexander X. VanFleet, Yasmine S. Humeda, Christian R. Schuetz
Summary: Injecting hydrogen peroxide as an alternative method to liquid contrast in establishing the stab wound tract enhances the ability of CT imaging to determine peritoneal penetration.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gaetano Rea, Francesco Lassandro, Roberta Lieto, Giorgio Bocchini, Federica Romano, Giacomo Sica, Tullio Valente, Emanuele Muto, Patrizia Murino, Antonio Pinto, Vincenzo Montesarchio, Maurizio Muto, Daniela Pacella, Ludovica Capitelli, Marialuisa Bocchino
Summary: The study found that around 71.4% of COVID-19 patients had relevant vascular events, with pulmonary embolism being the most common, and significantly higher incidence in ICU patients. In addition, cases of ischemic infarctions at multiple sites, systemic venous thrombosis, and incidental findings such as small-sized arterial aneurysms were detected, suggesting that COVID-19 affects the vascular system of patients.
EUROPEAN RADIOLOGY
(2021)
Article
Health Care Sciences & Services
Roman Kuruc, Andrea Szoradova, Jan Sikuta, Lubomir Mikulas, Jozef Sidlo
Summary: The objective of this study was to assess the reliability and accuracy of CT scan results in detecting trauma for forensic purposes. The study found a high correlation between CT scan results and autopsy findings in cases of traumatic deaths, although some discrepancies were still observed.
Article
Clinical Neurology
Gregory W. J. Hawryluk, Jamshid Ghajar
Summary: The Brain Trauma Foundation (BTF) Guidelines for the Management of Severe Head Injury were the first clinical practice guidelines published by any surgical specialty, and have been widely adopted worldwide. Implementation of these guidelines has been associated with a 50% reduction in mortality and reduced costs of patient care. Despite their success, the lack of high-quality clinical research and innovative diagnostics and treatments limits the generation of substantially new recommendations.
Article
Critical Care Medicine
Shane Smith, Laura Allen, Kosar Khwaja, Emilie Joos, Chad G. Ball, Paul T. Engels, Faysal Naji, Jacinthe Lampron, Sandy Widder, Sam Minor, Samuel Jessula, Neil G. Parry, Kelly N. Vogt
Summary: This study investigated the nature and management of vascular injuries at trauma centers across Canada. The findings revealed variability in injury mechanisms, management strategies, specialty responsible for management, and outcomes, highlighting the importance of practice change and knowledge translation.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Article
Health Care Sciences & Services
Siri Wiig, Karina Aase, Stephen Billett, Carolyn Canfield, Olav Roise, Ove Nja, Veslemoy Guise, Cecilie Haraldseid-Driftland, Eline Ree, Janet E. Anderson, Carl Macrae
BMC HEALTH SERVICES RESEARCH
(2020)
Article
Clinical Neurology
Mette Haldrup, Stig Dyrskog, Mathias Moller Thygesen, Hans Kirkegaard, Helge Kasch, Mikkel Mylius Rasmussen
JOURNAL OF NEUROSURGERY-SPINE
(2020)
Review
Emergency Medicine
Elisabeth Jeppesen, Valdemar Vea Iversen, Ingrid Schroder Hansen, Eirik Reierth, Torben Wisborg
SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE
(2020)
Article
Critical Care Medicine
Mathias Cuevas-Ostrem, Olav Roise, Torben Wisborg, Elisabeth Jeppesen
Summary: Geriatric trauma patients in Norway have higher mortality rates, receive less advanced prehospital treatment and transport, and have a lower trauma team activation rate compared to adult trauma patients. This study highlights the need for further exploration and understanding of these differences despite the well-established trauma system in the country.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Clinical Neurology
Jacob Horsager, Uwe Walter, Tatyana D. Fedorova, Katrine B. Andersen, Casper Skjaerbaek, Karoline Knudsen, Niels Okkels, Paul Von Weitzel-Mudersbach, Stig Eric Dyrskog, Bo Bergholt, Per Borghammer
Summary: There was no significant difference in the mean left and right vagus CSA between PD and HC groups. The right vagus CSA was significantly larger than the left in both groups. Sex-adjusted right vagus CSA was significantly smaller in the PD group, while the left vagus CSA did not show significant reduction.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Mathias Moller Thygesen, Torben Ellegaard Lund, Irene Klaerke Mikkelsen, Helge Kasch, Rikke Beese Dalby, Stig Eric Dyrskog, Michael Pedersen, Mikkel Mylius Rasmussen
Summary: This study aimed to establish a DKI protocol for acute SCI and found a significant correlation between decreasing mean kurtosis values at the injury site of the spinal cord and higher grade of disability in patients.
ACTA NEUROCHIRURGICA
(2022)
Article
Health Care Sciences & Services
Inger Marie Waal Nilsbakken, Stephen Sollid, Torben Wisborg, Elisabeth Jeppesen
Summary: This project aims to assess the initial pathways of injured patients through the trauma system in Norway and explore the differences between urban and rural areas. The study will provide new knowledge on existing quality indicators and contribute to the further development of the Norwegian trauma system.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Medicine, Research & Experimental
Mette Haldrup, Niwar Mohamad, Mads Rasmussen, Line Thorup, Stig Dyrskog, Claus Ziegler Simonsen, Rares Miscov, Carsten Reidies Bjarkam, Mads Gronhoj, Frantz Rom Poulsen, Anders Rosendal Korshoj
Summary: This study is a randomized controlled trial evaluating the efficacy and safety of active irrigation in external ventricular drainage using the IRRAflow system for patients with IVH. The study aims to assess the time to catheter occlusion, clearance of ventricular blood, rates of infection and shunt dependency, and patient outcomes.
Review
Clinical Neurology
Mette Haldrup, Rares Miscov, Niwar Mohamad, Mads Rasmussen, Stig Dyrskog, Claus Ziegler Simonsen, Mads Gronhoj, Frantz Rom Poulsen, Carsten Reidies Bjarkam, Birgit Debrabant, Anders Rosendal Korshoj
Summary: This review and meta-analysis evaluate the effects of external ventricular drainage (EVD) and intraventricular fibrinolysis (IVF) on complications and clinical outcomes of intraventricular hemorrhage (IVH) treatment. The results show that antibiotic-coated catheters are more effective in preventing infection compared to tunnelled/uncoated catheters, and rifampicin-coated catheters are more effective than silver-impregnated catheters. IVF promotes hematoma clearance, reduces mortality, improves functional outcomes, and decreases the rate of catheter occlusion.
WORLD NEUROSURGERY
(2023)
Article
Medicine, General & Internal
Mette Haldrup, Mads Rasmussen, Niwar Mohamad, Stig Dyrskog, Line Thorup, Nikola Mikic, Joakim Wismann, Mads Gronhoj, Frantz Rom Poulsen, Mojtaba Nazari, Naveed Ur Rehman, Claus Ziegler Simonsen, Anders Rosendal Korshoj
Summary: This randomized clinical trial compared intraventricular lavage with standard drainage and found that intraventricular lavage was associated with a significantly increased number of severe adverse events. Caution is recommended when using the device to ensure patient safety.
Article
Clinical Neurology
Thea Overgaard Wichmann, Helge Kasch, Stig Dyrskog, Kristian Hoy, Bjarne Kuno Moller, Jan Krog, Hans Jurgen Hoffmann, Claus Vinter Bodker Hviid, Mikkel Mylius Rasmussen
Summary: This study compares the feasibility of using cerebrospinal fluid (CSF) and peripheral blood (PB) as sample media for measuring biomarkers in traumatic spinal cord injury (TSCI). The results suggest that GFAP is a potential diagnostic biomarker that can be measured in both CSF and PB.
ACTA NEUROCHIRURGICA
(2023)
Article
Clinical Neurology
Thea Overgaard Wichmann, Helge Kasch, Stig Dyrskog, Kristian Hoy, Jan Krog, Bjarne Kuno Moller, Hans Jurgen Hoffmann, Claus Vinter Bodker Hvlid, Mikkel Mylius Rasmussen
Article
Clinical Neurology
Thea Overgaard Wichmann, Helge Kasch, Stig Dyrskog, Kristian Hoy, Bjarne Kuno Moller, Jan Krog, Claus Vinter Bodker Hviid, Hans Jurgen Hoffmann, Mikkel Mylius Rasmussen
Summary: This study aimed to describe the inflammatory responses and blood-spinal cord barrier (BSCB) integrity in human traumatic spinal cord injury (TSCI). The results showed that TSCI mainly triggers innate inflammatory responses that resolve over time, although some patients still exhibit non-resolving inflammation in the cerebrospinal fluid (CSF). Furthermore, BSCB disruption was observed in some TSCI patients.
ACTA NEUROCHIRURGICA
(2022)
Review
Emergency Medicine
Kenneth A. Eilertsen, Morten Winberg, Elisabeth Jeppesen, Gyri Hval, Torben Wisborg
Summary: Despite low-quality evidence, most of the studies consistently indicated that the use of commercial tourniquets in civilian settings to control life-threatening extremity hemorrhage seemed to be associated with improved survival, reduced need for blood transfusion, and few and transient adverse effects.
PREHOSPITAL AND DISASTER MEDICINE
(2021)
Article
Immunology
Thomas Birkelund, Rakel F. Johansen, Dorte G. Illum, Stig Eric Dyrskog, Jakob A. Ostergaard, Travis M. Falconer, Chris Andersen, Helena Fridholm, Soren Overballe-Petersen, Jorgen S. Jensen
Summary: This article describes a fatal case of poisoning in a patient who consumed coconut water contaminated by the fungus Arthrinium saccharicola, leading to severe symptoms and death. Clinical findings and forensic analysis are presented.
EMERGING INFECTIOUS DISEASES
(2021)