Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV

Intracellular complement activation—An alarm raising mechanism?

(2018) M.P. Reichhardt et al.   SEMINARS IN IMMUNOLOGY

Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion

(2018) Wenbiao Wang et al.   Nature Communications

Blockade of the C5a–C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV

(2018) Yuting Jiang et al.   Emerging Microbes & Infections

EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex

(2017) Wenbiao Wang et al.   PLoS Pathogens

The H7N9 influenza A virus infection results in lethal inflammation in the mammalian host via the NLRP3-caspase-1 inflammasome

(2017) Rongrong Ren et al.   Scientific Reports

Pyroptosis

(2016) Lieselotte Vande Walle et al.   CURRENT BIOLOGY

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome

(2016) Anita Pinar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRP3 is Required for Complement-Mediated Caspase-1 and IL-1beta Activation in ICH

(2016) Sheng-Tao Yao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Inflammasome-Derived Exosomes Activate NF-κB Signaling in Macrophages

(2016) Yuehui Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

(2016) G. Arbore et al.   SCIENCE

Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus

(2015) Guangyu Zhao et al.   PLoS One

Clinical Course and Outcomes of Critically Ill Patients With Middle East Respiratory Syndrome Coronavirus Infection

(2014) Yaseen M. Arabi et al.   ANNALS OF INTERNAL MEDICINE

Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description

(2014) Mohammad Mousa Al-Abdallat et al.   CLINICAL INFECTIOUS DISEASES

Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release

(2014) E. O. Samstad et al.   JOURNAL OF IMMUNOLOGY

Brief Report: Granulocyte-Macrophage Colony-Stimulating Factor Drives Monosodium Urate Monohydrate Crystal-Induced Inflammatory Macrophage Differentiation and NLRP3 Inflammasome Up-Regulation in an In Vivo Mouse Model

(2014) Odette M. Shaw et al.   Arthritis & Rheumatology

C3a modulates IL-1  secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation

(2013) E. Asgari et al.   BLOOD

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

(2013) M. Kathryn Liszewski et al.   IMMUNITY

Active Replication of Middle East Respiratory Syndrome Coronavirus and Aberrant Induction of Inflammatory Cytokines and Chemokines in Human Macrophages: Implications for Pathogenesis

(2013) Jie Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission

(2013) Benoit Guery et al.   LANCET

Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study

(2013) Abdullah Assiri et al.   LANCET INFECTIOUS DISEASES

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

(2013) Julie L. McAuley et al.   PLoS Pathogens

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

Fungal pathogen recognition by the NLRP3 inflammasome

(2010) Sophie Joly et al.   Virulence

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE