Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus

In addition to the impact of Bacillus Calmette-Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.