Article
Oncology
Matthew Gallitto, Michelle Savacool, Albert Lee, Tony J. C. Wang, Michael B. Sisti
Summary: This study reports on the feasibility of using GammaKnife ICON for five-fraction SRS in the management of newly diagnosed GBM. Progression free survival was comparable to historical data without significant radiation-induced toxicities.
Article
Clinical Neurology
Michael Yan, Lori Holden, Jay Detsky, Chia -Lin Tseng, Hany Soliman, Sten Myrehaug, Zain Husain, Sunit Das, Collins Yeboah, Nir Lipsman, Mark Ruschin, Arjun Sahgal
Summary: This study retrospectively reviewed patients who received fractionated re-irradiation using Gamma Knife Icon, which demonstrated a safe and effective method for the re-irradiation of complex primary intracranial tumors, minimizing the potential for serious late effects.
JOURNAL OF NEUROSURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyeong Cheol Moon, Hyun-Tai Chung, Byung Jun Min, Yun-Sik Dho
Summary: This study evaluated the characteristics of three mask fixation methods (Plain, Folded, and Wide) for the Leksell Gamma Knife (LGK) Icon(TM). The results showed that the Folded method is recommended for tight fixation of patients, while the Wide method can be considered if patient comfort is a priority.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
David J. Schlesinger, Jason C. Sanders, Donald A. Muller, Hakan Nordstrom, Jason P. Sheehan
Summary: The study characterized the long-term performance of a Gamma Knife Perfexion/Icon unit and used statistical process control (SPC) methods to detect changes in performance at levels lower than existing QA and internal manufacturer performance tolerances. The results showed that changes in positioning behavior could be observed over time, allowing for early identification and possibly prediction of faults beyond control system tolerance.
Article
Medicine, General & Internal
Jameson T. Mendel, Samuel Schroeder, Aaron Plitt, Ankur Patel, Mindy Joo, Strahinja Stojadinovic, Tu Dan, Robert Timmerman, Toral R. Patel, Zabi Wardak
Summary: The Gamma Knife Icon offers a frameless solution for the treatment of various intracranial lesions, significantly increasing treatment efficiency and daily volume on a single machine. It is particularly suitable for patients requiring precise radiosurgery.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Neurosciences
Fabio Barone, Francesco Inserra, Gianluca Scalia, Massimo Ippolito, Sebastiano Cosentino, Antonio Crea, Maria Gabriella Sabini, Lucia Valastro, Iolanda Valeria Patti, Stefania Mele, Grazia Acquaviva, Alessandra Tocco, Maria Tamburo, Francesca Graziano, Ottavio S. Tomasi, Rosario Maugeri, Gerardo Iacopino, Salvatore Cicero, Lidia Strigari, Giuseppe Emmanuele Umana
Summary: Ga-68-DOTATOC PET/CT proved to be a valuable tool in evaluating meningioma diagnosis and follow-up assessment for primary radiosurgery, with most cases showing a biological response of the tumor to Gamma Knife treatment.
Article
Neurosciences
Maneet Gill, Manish Sharma, Raj Ratan
Summary: Gamma knife radiosurgery was developed based on the principles of stereotactic radiosurgery proposed by Swedish physician Lars Leksell. The Perfexion model has been widely used in India but has now been replaced with the newer ICON model, which incorporates Cone-Beam Computed Tomography (CBCT) for non-invasive and accurate skull immobilization. Despite some challenges, the use of the ICON model has been successful in frameless gamma knife surgeries in around 25% of planned patients. Rating: 8/10.
Article
Clinical Neurology
Adomas Bunevicius, Darrah Sheehan, Mary Lee Vance, David Schlesinger, Jason P. Sheehan
Summary: This study found that technological advancements and growing center experience were important factors for improved endocrine remission rates in patients with CD.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
Akiyoshi Ogino, Ajay Niranjan, Hideyuki Kano, John C. Flickinger, L. Dade Lunsford
Summary: The study evaluated factors affecting tumor control and complications in craniopharyngioma SRS. Results showed that ensuring at least 85% of the tumor received >= 12 Gy improved tumor control rates, even with a distance < 3 mm from the optic system. Higher conformity index did not lead to better tumor control.
JOURNAL OF NEURO-ONCOLOGY
(2021)
Article
Clinical Neurology
Michelle E. De Witt, Carlos R. Goulart, Michael D. Mix, Gaddum D. Reddy
Summary: This study retrospectively analyzed all patients who underwent Gamma Knife treatments at the institution between January 2013 and August 2019, and found that among patients who received brain imaging within 30 days for symptomatic complaints, most images showed no significant changes and the rate of significant complications was exceedingly low.
WORLD NEUROSURGERY
(2021)
Article
Oncology
Junyi Fu, Jiamin Zeng, Minyi Huang, Shunyao Liang, Yong He, Longchang Xie, Yinhui Deng, Jinxiu Yu
Summary: This study compared the long-term outcomes of primary versus postoperative Gamma Knife radiosurgery (GKRS) for benign meningiomas. The results showed that primary GKRS provided similar radiological and clinical outcomes, as well as similar complication rates compared with postoperative GKRS. For selected patients with benign meningiomas, GKRS could be considered as an alternative primary treatment.
Article
Oncology
Tugce Kutuk, Rupesh Kotecha, Ranjini Tolakanahalli, D. Jay J. Wieczorek, Yongsook C. Lee, Manmeet S. Ahluwalia, Matthew D. Hall, Michael W. McDermott, Haley Appel, Alonso N. Gutierrez, Minesh P. Mehta, Martin C. Tom
Summary: This study compared the clinical outcomes of mask immobilization with zero-SM and standard zero-SM frame immobilization in the treatment of BM. The results showed that there was no significant difference in FFLF and radiation necrosis rates between mask immobilization and frame immobilization for BM with 0.5-2.0 cm diameter.
Article
Oncology
Yanli Li, Lisha Wu, Tingting Quan, Junyi Fu, Linhui Cao, Xi Li, Shunyao Liang, Minyi Huang, Yinhui Deng, Jinxiu Yu
Summary: This study aimed to report the characteristic of tumor regrowth after gamma knife radiosurgery (GKRS) and outcomes of repeat GKRS in nonfunctioning pituitary adenomas (NFPAs). The study found that parasellar invasion and tumor margin dose (<12 Gy) were independent risk factors for tumor regrowth after GKRS. Repeat GKRS might be effective on tumor control for selected patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Serena Ammendola, Paola Chiara Rizzo, Michele Longhi, Emanuele Zivelonghi, Serena Pedron, Giampietro Pinna, Francesco Sala, Antonio Nicolato, Aldo Scarpa, Valeria Barresi
Summary: The loss of H3K27me3 in meningiomas is significantly associated with tumor progression and shorter PFS after stereotactic radiosurgery (SRS), suggesting a weaker response to SRS in these cases.
Article
Clinical Neurology
Mihir Gupta, Varun Sagi, Aditya Mittal, Anudeep Yekula, Devan Hawkins, Justin Shimizu, Pate J. Duddleston, Kathleen Thomas, Steven J. Goetsch, John F. Alksne, David W. Hodgens, Kenneth Ott, Kenneth T. Shimizu, Christopher Duma, Sharona Ben-Haim
Summary: In this study, the authors reviewed outcomes among 30 patients who underwent three or more Gamma Knife radiosurgery treatments for recurrent trigeminal neuralgia. The results showed that while time to pain relief was longer after the third treatment, time to pain recurrence remained similar across successive treatments, with the majority of patients achieving complete or partial pain relief after the third treatment.
JOURNAL OF NEUROSURGERY
(2021)
Letter
Clinical Neurology
Julien Francisco Zaldivar-Jolissaint, Marc Kotowski, Philippe Maeder, Marc Levivier, Roy Thomas Daniel
ACTA NEUROCHIRURGICA
(2015)
Article
Clinical Neurology
Frederic Rossi-Mossuti, Urs Fisch, Patrick Schoettker, Marinella Gugliotta, Marc Morard, Philippe Schucht, Bawarjan Schatlo, Marc Levivier, Bernhard Walder, Javier Fandino
JOURNAL OF NEUROLOGICAL SURGERY PART A-CENTRAL EUROPEAN NEUROSURGERY
(2016)
Review
Clinical Neurology
Daniele Starnoni, Roy Thomas Daniel, Laura Marino, Nelly Pitteloud, Marc Levivier, Mahmoud Messerer
ACTA NEUROCHIRURGICA
(2016)
Article
Clinical Neurology
A. Rocca, J. -M. Pignat, L. Berney, J. Johr, D. Van de Ville, R. T. Daniel, M. Levivier, L. Hirt, A. R. Luft, E. Grouzmann, K. Diserens
Review
Oncology
A. Tarabay, G. Cossu, M. Berhouma, M. Levivier, R. T. Daniel, M. Messerer
JOURNAL OF NEURO-ONCOLOGY
(2016)
Article
Clinical Neurology
Jean Regis, Constantin Tuleasca, Noemie Resseguier, Romain Carron, Anne Donnet, Jean Gaudart, Marc Levivier
JOURNAL OF NEUROSURGERY
(2016)
Article
Clinical Neurology
M. Messerer, G. Cossu, P. Pasche, C. Ikonomidis, C. Simon, E. Pralong, M. George, M. Levivier, R. T. Daniel
Review
Clinical Neurology
M. Messerer, B. Richoz, G. Cossu, F. Dhermain, A. F. Hottinger, F. Parker, M. Levivier, R. T. Daniel
Article
Neurosciences
Jean Regis, Constantin Tuleasca, Noemie Resseguier, Romain Carron, Anne Donnet, Shoji Yomo, Jean Gaudart, Marc Levivier
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY
(2016)
Article
Neurosciences
Yves Yamgoue, Etienne Pralong, Marc Levivier, Jocelyne Bloch
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY
(2016)
Article
Clinical Neurology
Julien Dimitriou, Marc Levivier, Marinella Gugliotta
WORLD NEUROSURGERY
(2016)
Correction
Clinical Neurology
David Kaul, Harun Badakhshi, Thierry Gevaert, Diana Pasemann, Volker Budach, Constantin Tuleasca, Arne Gruen, Vikas Prasad, Marc Levivier, Markus Kufeld
ACTA NEUROCHIRURGICA
(2015)
Review
Anesthesiology
Giulia Cossu, Mahmoud Messerer, Nino Stocchetti, Marc Levivier, Roy T. Daniel, Mauro Oddo
MINERVA ANESTESIOLOGICA
(2016)
Article
Endocrinology & Metabolism
Constantin Tuleasca, Yves Jaquet, Valerie Schweizer, Laura Negretti, Vera Magaddino, Philippe Maeder, Karim-Alexandre Abid, Benoit Lhermitte, Eric Grouzmann, Marc Levivier
HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
(2016)
