Article
Chemistry, Multidisciplinary
Rui Chen, Xirui Chen, Yaofeng Zhou, Tong Lin, Yuankui Leng, Xiaolin Huang, Yonghua Xiong
Summary: A three-in-one multifunctional catalytic colorimetric nanohybrid was developed as promising signal reporters for ultrasensitive immunochromatographic disease diagnostics.
Article
Chemistry, Analytical
Yu Muto, Gen Hirao, Tamotsu Zako
Summary: The study presented a AuNP-based signal-amplifying sandwich biosensor for detecting target molecules without the need for conformational changes in ligands. Thrombin was used as a model target, triggering an extension reaction via hybridization of two probes and subsequently RNA synthesis initiation. The amplified RNA drives aggregation or dispersion of the AuNPs, leading to observable color differences in the solution. This detection system can be universally applied to a wide range of ligands due to its ligand-independent design.
Article
Chemistry, Analytical
Shan Jiang, Lvxia Zhang, Jizhou Li, Hui Ouyang, Zhifeng Fu
Summary: A sensitive immunochromatographic test strip (ITS) for detecting AFB(1) using dendritic platinum nanoparticles as pressure/colorimetric dual-readout probes was developed. The ITS showed a detection range of 0.05-10 ng mL(-1) with a detection limit of 0.03 ng mL(-1) for AFB(1). It was successfully utilized for detecting AFB(1) in herbal medicine samples, demonstrating its reliability for real sample detection and potential applications in drug and food quality control, pollutants monitoring, and medical diagnosis.
Review
Chemistry, Analytical
Xingyue Liu, Xinyi Liang, Jing Yu, Keying Xu, Jia-Wei Shen, Wei Duan, Jingbin Zeng
Summary: This review summarizes the recent progress in colorimetric sensors based on noble metal-based bimetallic nanoparticles (NMBNPs). The synthesis approaches of NMBNPs are introduced and the main sensing strategies utilizing their unique properties for colorimetric detection are discussed. Challenges and opportunities for the future development of NMBNPs-based colorimetric sensors are proposed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Yuan Cheng, Lingling Guo, Aihong Wu, Xinxin Xu, Liqiang Liu, Chuanlai Xu, Hua Kuang, Liguang Xu
Summary: In this study, a hapten was designed and coupled with a carrier protein to synthesize an immunogen and coating antigen. A monoclonal antibody was fabricated and assessed for its performance. A colloidal gold nanoparticle immunochromatographic test strip (CGN-ICTS) was developed and shown to have high sensitivity for detecting tolfenpyrad residues in food samples.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Review
Biotechnology & Applied Microbiology
V. G. Panferov, I. V. Safenkova, A. V. Zherdev, B. B. Dzantiev
Summary: This review discusses modern methodological solutions for ensuring high sensitivity of immunochromatographic assay (ICA) methods based on the use of nanoparticle markers and colorimetric detection, focusing on lowering the detection limit amplification of the detectable signal generated by a single nanoparticle. Different approaches are examined for their advantages and limitations, showing that the use of these methods can decrease the detection limit of ICA by 1-3 orders of magnitude, making it competitive with instrumental methods of analysis.
APPLIED BIOCHEMISTRY AND MICROBIOLOGY
(2021)
Article
Chemistry, Analytical
Hui Zhou, Cong He, Zhenfeng Li, Jingqian Huo, Yu Xue, Xiaotong Xu, Meng Qi, Lai Chen, Bruce D. Hammock, Jinlin Zhang
Summary: In this study, a gold nanoparticle immunochromatographic strip method was developed for on-site rapid detection and quantification of 2,4-D levels in environmental samples. The method also allowed for qualitative analysis of 2,4-D. The assay demonstrated fast, simple, accurate, and reliable results, with analysis completed in about ten minutes. Additionally, the use of nanobody technology in this study provided a stable and renewable supply of antibodies.
Article
Engineering, Environmental
Qing Yu, Jiaxuan Li, Shuai Zheng, Xuan Xia, Changyue Xu, Chaoguang Wang, Chongwen Wang, Bing Gu
Summary: The sudden outbreak of monkeypox in 2022 highlights the need for rapid and sensitive virus detection technology. This study presents a colorimetric/surface-enhanced Raman scattering (SERS) dual-signal co-enhanced immunochromatographic assay (ICA) for the flexible, ultrasensitive, and accurate detection of monkeypox virus (MPXV) in complex samples. The proposed assay, which combines colorimetric and SERS signals, offers quick identification and quantitative detection of MPXV with high sensitivity and accuracy.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Chao Li, Mengyang Zhou, Haoyu Wang, Jie Wang, Lin Huang
Summary: This study developed a colorimetric biosensor for the visual detection of exosomes, with dual signal amplification using rolling circle amplification (RCA). The method exhibited high sensitivity and specificity, and showed potential for clinical diagnosis in distinguishing healthy individuals from leukemia patients.
Article
Medicine, Research & Experimental
Hong Duan, Tongtong Ma, Xiaolin Huang, Bao Gao, Lingyan Zheng, Xirui Chen, Yonghua Xiong, Xiaoyuan Chen
Summary: This study presents a pH-regulated gold in situ growth (GISG) strategy to amplify the colorimetric signal and improve the performance of traditional gold nanoparticle-based immunochromatographic assay (AuNP-ICA). By lowering the pH of the growth solution, the reducibility of hydroxylamine is weakened, resulting in the crystallization and growth of Au3+ on the AuNP surface instead of self-nucleation. The proposed GISG strategy shows improved sensitivity, low background, robust operation, and good reproducibility. It has the potential to enable ultrasensitive and rapid diagnosis of viral infections and redefine immunochromatographic diagnostics.
Article
Food Science & Technology
Han Wang, Yu Zheng, Hong-Lin Ren, Yi-Ran Xiao, Cong Wang, Jiang Chang, Yu-Xi Guo, Pan Hu, Yan-Song Li, Zeng-Shan Liu, Shi-Ying Lu
Summary: A lateral flow immunochromatographic strip targeting on virulence gene ail was developed using recombinase polymerase amplification and quantum dot nanobeads for rapid detection of pathogenic Yersinia enterocolitica in meat samples with high sensitivity and accuracy.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Hao Liu, Fang Ji, Shou-Nian Ding
Summary: This study presents a carbon black-based immunochromatographic test strip (CB-ICTS) for the detection of SFTSV, which is both quick and easy to operate. The CB-ICTS showed a detection range of 0.1-1000 ng mL(-1) for SFTSV with a limit of detection of 100 pg mL(-1). The study demonstrated the specificity and effectiveness of the CB-ICTS for early detection of SFTSV through evaluating biomarkers and comparing with PCR results.
Article
Nanoscience & Nanotechnology
Seunghyeon Kim, Hadley D. Sikes
Summary: A dual photocatalyst signal amplification strategy was developed to achieve time-independent colorimetric biodetection in paper-based tests. By controlling the light dose and improving the photocatalytic efficiency, a 100- to 500-fold enhancement in sensitivity was obtained.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Microbiology
Xiaoli Yu, Yanping Jiang, Songsong Zhang, Caihong Wang, Ruichong Wang, Lanlan Zhang, Siming Tao, Wen Cui, Jiaxuan Li, Xinyuan Qiao
Summary: A colloidal gold immunochromatographic strip with enhanced signal was developed for the detection of bovine parvovirus (BPV). This strip showed 10 times higher sensitivity than the traditional strip, with a minimum detection amount of 10(2) TCID50 for BPV. The strip exhibited high specificity and repeatability, with a concordance rate of 99.29% compared to PCR.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Infectious Diseases
Huaming Xu, Hao Tang, Rongrong Li, Zhaoxin Xia, Wensu Yang, Yi Zhu, Zhen Liu, Guoping Lu, Shenwang Ni, Jilu Shen
Summary: This study developed a new laboratory assay for rapid and accurate identification of carbapenemase-mediated antimicrobial resistance. The method utilized CRISPR-Cas12a and lateral flow immunochromatographic strip, and demonstrated high sensitivity and specificity. It is a simple and cost-effective approach for clinical use.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Chemistry, Multidisciplinary
Rui Chen, Xirui Chen, Yaofeng Zhou, Tong Lin, Yuankui Leng, Xiaolin Huang, Yonghua Xiong
Summary: A three-in-one multifunctional catalytic colorimetric nanohybrid was developed as promising signal reporters for ultrasensitive immunochromatographic disease diagnostics.
Review
Chemistry, Multidisciplinary
Yaofeng Zhou, Siyu Fan, Lili Feng, Xiaolin Huang, Xiaoyuan Chen
Summary: Various strategies have been developed to increase the efficiency of the intratumoral Fenton reaction in chemodynamic therapy (CDT), enhancing the therapeutic efficacy. The introduction of reinforcement strategies can improve treatment efficiency and promote the development of enhanced CDT-based multimodal anticancer therapies.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Jing Chen, Liangwen Hao, Jiaqi Hu, Kang Zhu, Yu Li, Sicheng Xiong, Xiaolin Huang, Yonghua Xiong, Ben Zhong Tang
Summary: A universal boronate-affinity crosslinking-amplified DLS immunoassay was developed for point-of-care glycoprotein detection, achieving ultrasensitive and rapid quantitative assay within 15 minutes. This approach combines antibody-coated magnetic nanoparticles for target capture and DLS signal transduction with phenylboronic acid-based boronate-affinity materials as crosslinking amplifiers, making it a promising strategy for extending DLS technique to detect glycoproteins even in challenging environments.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biophysics
Yaofeng Zhou, Xiaolin Huang, Xinyu Hu, Weipeng Tong, Yuankui Leng, Yonghua Xiong
Summary: The article discusses the fabrication of dual-modal sensing technologies and their advantages in analytical efficiency, detection range, accuracy, and application flexibility, highlighting colorimetric and fluorescent signals as two popular output signals with distinctive advantages. It also explores the wide applications of dual-modal sensing technologies in disease diagnosis, environmental monitoring, and food safety, discussing the complementary and synergistic effects of the two output signals over the past decade.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Materials Science, Multidisciplinary
Ruoyao Zhang, Xiaolin Huang, Chao Chen, Ryan T. K. Kwok, Jacky W. Y. Lam, Ben Zhong Tang
Summary: Cancer is a severe disease with unique biological features that can be accurately discriminated using fluorescent imaging technologies, particularly through aggregation-induced emission (AIE) technique. AIEgens, non-emissive in molecular state but enhanced emission in aggregated state, have emerged as powerful tools in cancer discrimination, overcoming limitations of conventional fluorescent dyes.
MATERIALS SCIENCE & ENGINEERING R-REPORTS
(2021)
Review
Medicine, Research & Experimental
Xirui Chen, Lu Ding, Xiaolin Huang, Yonghua Xiong
Summary: This article introduces the application of engineered noble metal nanoparticles in improving immunoassay sensitivity. By modulating the physical parameters of nanoparticles, including size, shape, composition, and external structure, the performance of immunoassay can be improved. Engineered nanoparticles have a wide range of applications in trace analysis.
Article
Biotechnology & Applied Microbiology
Jiaqi Hu, Lu Ding, Jing Chen, Jinhua Fu, Kang Zhu, Qian Guo, Xiaolin Huang, Yonghua Xiong
Summary: A new dynamic light scattering (DLS) immunosensing technology was reported for rapid and sensitive detection of NT-proBNP. Boronate affinity recognition was used to amplify nanoparticle aggregation for highly sensitive DLS transduction. The developed DLS immunosensor showed ultrahigh sensitivity, fast response time, and small sample consumption.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Biophysics
Kang Zhu, Jing Chen, Jiaqi Hu, Sicheng Xiong, Lifeng Zeng, Xiaolin Huang, Yonghua Xiong
Summary: This study introduces an innovative BAR-enhanced DLS biosensor for ultra-sensitive PCT detection, showing high sensitivity and specificity. The sensor offers quick total detection time, low sample consumption, and applicability for a broader range of patients and urgent cases.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Food Science & Technology
Xujing Guo, Xirui Chen, Rui Chen, Yujie Tu, Tianying Lu, Yuqian Guo, Liang Guo, Yonghua Xiong, Xiaolin Huang, Ben Zhong Tang
Summary: In this study, a paper-based smart sensing chip was developed for real-time monitoring of food freshness. By detecting color and fluorescence changes, ammonia vapors can be sensitively detected, demonstrating the feasibility of the paper chip for evaluating food spoilage degree.
Article
Food Science & Technology
Weipeng Tong, Hanpeng Xiong, Hao Fang, Yuhao Wu, Haichuan Li, Xiaolin Huang, Yuankui Leng, Yonghua Xiong
Summary: In order to achieve high-throughput analysis of mycotoxins, there is a great need for point-of-care (POC) methods that do not require expensive instruments or specialized technicians. The conventional enzyme-linked immunosorbent assay (ELISA), which is widely used for screening, has low sensitivity and is affected by competing antigens. In this study, we developed a plasmonic-photothermal ELISA that uses color-temperature dual-modal signals for highly sensitive detection of ochratoxin A (OTA), with the signal amplified by a bifunctional M13 phage. Under optimal conditions, the colorimetric and photothermal signals showed good dynamic linearity for quantitative OTA detection, with detection limits of 12.1 and 8.6 pg mL(-1), respectively. Additionally, the proposed ELISA could be visually determined with a cutoff limit of 78 pg mL(-1) based on a distinct color change from deep blue to red. The method also showed high accuracy and robustness when applied to OTA-spiked corn samples. Overall, this strategy provides a promising method for eco-friendly and sensitive POC screening of OTA, and can be easily adapted for other analytes by changing the specific mimotope sequence.
Article
Food Science & Technology
Hanpeng Xiong, Ping Chen, Xirui Chen, Xuanang Shen, Xiaolin Huang, Yonghua Xiong, Yu Su
Summary: In this study, a novel aggregation-induced emission (AIE)-based sandwich lateral flow immunoassay (LFIA) was introduced for the sensitive detection of Staphylococcal enterotoxin A (SEA) using red-emissive AIE nanoparticles (AIENPs) as the fluorescent nanoprobe. The ultrasensitive detection of SEA in pasteurised milk was achieved within 20 min with a limit of detection of 0.04 ng mL(-1). The proposed PBA-AIENP-LFIA platform shows promise as a potent tool for the identification of additional compounds in food samples as well as an ideal test method for on-site detections.
Article
Food Science & Technology
Ge Xu, Xiaojing Fan, Xirui Chen, Zilong Liu, Guoxin Chen, Xiaxia Wei, Xiangmin Li, Yuankui Leng, Yonghua Xiong, Xiaolin Huang
Summary: In this study, ultrabright fluorescent microbeads (AIEMBs) were developed by encapsulating a green-emitting fluorophore with aggregation-induced emission (AIE) characteristic in polymer nanoparticles. The AIEMBs were then used as signal reporters in a competitive LFIA for the highly sensitive screening of fumonisin B1 (FB1) in corn samples. The AIE-LFIA demonstrated high sensitivity, excellent selectivity, good accuracy, and high reliability, indicating a promising platform for FB1 screening.
Article
Chemistry, Analytical
Wenchao Zhan, Yu Su, Xirui Chen, Hanpeng Xiong, Xiaxia Wei, Xiaolin Huang, Yonghua Xiong
Summary: A hydrogel probe encapsulating aggregation-induced emission luminogen (AIEgen) was developed for ultrasensitive detection of Hg2+, with improved sensitivity through the use of hydrophilic hydrogels and spatial networks. The probe exhibited high specificity, accuracy and precision in detecting Hg2+ in real-world water samples, with a sensitivity 4-fold higher than that of pure AIEgen probes. This TR hydrogel-based chemosensor holds promising potential as a robust, fast and effective platform for sensitive Hg2+ detection.
Article
Medicine, Research & Experimental
Hong Duan, Tongtong Ma, Xiaolin Huang, Bao Gao, Lingyan Zheng, Xirui Chen, Yonghua Xiong, Xiaoyuan Chen
Summary: This study presents a pH-regulated gold in situ growth (GISG) strategy to amplify the colorimetric signal and improve the performance of traditional gold nanoparticle-based immunochromatographic assay (AuNP-ICA). By lowering the pH of the growth solution, the reducibility of hydroxylamine is weakened, resulting in the crystallization and growth of Au3+ on the AuNP surface instead of self-nucleation. The proposed GISG strategy shows improved sensitivity, low background, robust operation, and good reproducibility. It has the potential to enable ultrasensitive and rapid diagnosis of viral infections and redefine immunochromatographic diagnostics.
Review
Chemistry, Multidisciplinary
Xiaolin Huang, Ruoyao Zhang, Chao Chen, Ryan T. K. Kwok, Ben Zhong Tang
Summary: This review discusses the latest progress of AIEgens in wash-free detection and bioimaging, presenting several important examples in different fields to demonstrate their potential. It highlights the design strategies and responsive mechanisms of AIEgens, while also delving into the current challenges and future directions in the field.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Review
Chemistry, Analytical
Claudia Campanale, Silvia Galafassi, Francesca Di Pippo, Iulian Pojar, Carmine Massarelli, Vito Felice Uricchio
Summary: Biodegradable plastic mulches (BDMs) have the potential to be an eco-friendly alternative to conventional plastic mulches in agriculture. However, their long-term impacts on soil ecosystems are still uncertain, and further research is needed. Incorporating BDMs into the soil may stimulate microbial activity, but there is also a risk of incomplete degradation and release of residual microplastics and additives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Yaxin Cao, Longyi Shao, Timothy P. Jones, Wenjing Deng, M. Santosh, Pengju Liu, Cheng-Xue Yang, Yaowei Li, Daizhou Zhang, Kelly Berube
Summary: The toxicity of fibrous particles in ambient air can be higher than other types of particles. Microfibers can be organic or inorganic and their presence in the atmosphere as a result of human activity raises concerns for environmental and public health. Accurate collection, identification, and understanding of the health hazards associated with these fibers are crucial for mitigation strategies and protection of public health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Chenchen Xie, Chen Meng, Huilin Liu, Baoguo Sun
Summary: The development of food hazard factor (FHF) detection has been moving towards on-site inspection and mobile law enforcement, calling for simple, fast, and affordable analysis technology to ensure food safety and quality. This review comprehensively summarizes the progress in research on smartphone-assisted MIP optosensors, focusing on the key issues of accuracy and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Guillem Peris-Pastor, Cristian Azorin, Jose Grau, Juan L. Benede, Alberto Chisvert
Summary: Green Analytical Chemistry plays an important role in every stage of method development, including sample preparation. Extraction techniques have evolved from conventional ones to a variety of miniaturized techniques in order to enhance analytical performance and ensure safety for operators and the environment. Green metric tools are used to evaluate the impact and sustainability of methods, with AGREEprep selected as the most suitable tool for evaluating published methods in various applications. The miniaturization of sample preparation strategies has led to the use of less and safer solvents, reduced waste generation and energy consumption, and improved portability and throughput.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Helena Hruskova, Roman Reminek, Frantisek Foret
Summary: This review article summarizes the progress and recent studies in offline electromigration preparative techniques between 2018 and 2023. It covers various techniques including electrophoresis, free-flow electrophoresis, isoelectric focusing, and isotachophoresis, providing theoretical aspects, trends, and solutions to existing limitations in each technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Ivneet Banga, Anirban Paul, Nathan Kodjo Mintah Churcher, Ruchita Mahesh Kumar, Sriram Muthukumar, Shalini Prasad
Summary: Breathomics is an emerging field that focuses on analyzing exhaled breath to diagnose and monitor respiratory diseases. Electrochemical sensors, with their high sensitivity, selectivity, and low cost, play a significant role in breathomics and can be integrated into portable devices for point-of-care diagnosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Fabjola Bilo, Paola Cirelli, Laura Borgese
Summary: This review explores the application of X-ray fluorescence (XRF) spectrometry for elemental analysis of particulate matter (PM) in air quality monitoring. It discusses the fundamentals of XRF, experimental configurations, PM sampling devices and substrate, sample preparation strategies, qualitative and quantitative analysis, as well as the challenges faced by XRF in becoming a reliable analytical technique for PM analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hakim Faraji
Summary: The dispersive liquid-liquid microextraction (DLLME) technique is widely popular in analytical chemistry due to its high efficiency, cost-effectiveness, and simplicity. Recent advancements have addressed the limitations of DLLME, incorporating greener solvents, innovative dispersion strategies, and simplified procedures. These changes have made DLLME a more sustainable and efficient technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli, Fotouh R. Mansour
Summary: Carbon nanomaterials (CNMs) have excellent capabilities in terms of adsorption, enhanced oxidation, and photocatalysis, attracting widespread attention in different fields. Metal-organic frameworks (MOFs) have been widely used due to their regular network structure, porous nature, and large specific surface area. However, the instability of MOFs in aqueous solutions limits their applications in chemical sensing. Recent studies have focused on increasing the stability of MOFs in water-based matrices through chemical modifications using CNMs.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Alexandra Pape, Oliver J. Schmitz
Summary: Low temperature plasmas based on dielectric barrier discharges have emerged as a recent development in ion source research. These ion sources are applicable to heat-sensitive analytes and can ionize a wide range of compounds. Despite intensive research on important parameters such as configuration, shape, size, and materials in the past two decades, the actual ionization mechanism for all plasma gases has not been fully elucidated. This review provides an overview of atmospheric pressure ion sources, with a focus on plasma and dielectric barrier discharge based ion sources, summarizing the reactions occurring in the plasma and discussing the applications developed by different research groups.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hai Xiong, Fengli Li, Linyu Zeng, Qiyu Lei
Summary: This review provides an overview of the emerging trends in the use of functional COF nanomaterials as biosensors for DNA/RNA detection. It summarizes the construction of DNA/RNA hybridized COF nanoprobes and their potential applications in bioanalyte detection, biosensing, biomarker imaging, and clinical biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Bing Yan
Summary: This article summarizes the recent progress in logic gate computing and operation based on multiple luminescence response and chemical sensing for lanthanide functionalized MOF hybrid systems. The article first describes multi-color luminescence and the subsequent multiple luminescence response. The basic concept of logic gate operation and the advantages of lanthanide-based hybrid materials are then introduced. Reports on logic gate operation using pure lanthanide MOFs are provided, followed by a detailed summary of logic gate operations using lanthanide functionalized MOF hybrid materials. Additionally, the article discusses the practical luminescent detection of analytes by correlating the luminescence responsive signals and the concentration of different analytes. Finally, the article concludes with a prospect for this topic.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Brij Mohan, Gurjaspreet Singh, Rakesh Kumar Gupta, Pawan Kumar Sharma, Alexander A. Solovev, Armando J. L. Pombeiro, Peng Ren
Summary: Porous materials, particularly hydrogen-bonded organic frameworks (HOFs), have gained significant attention due to their versatile applications and unique properties such as well-defined crystalline structure and easy regeneration processes. This article provides a comprehensive overview of HOFs, including synthesis methods, hydrogen bonding motifs, recent advancements, and potential applications, offering valuable guidance for further exploration in this dynamic field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
