Review
Chemistry, Multidisciplinary
Joao Ferreira Gil, Carla Sofia Moura, Vania Silverio, Gil Goncalves, Helder A. Santos
Summary: Cancer is a leading cause of death worldwide, with millions of lives lost every year. However, the understanding of physiological and biomechanical processes underlying tumors remains limited, hindering the development of effective therapies. 3D tumor-on-a-chip (ToC) models have the potential to address these challenges by integrating various technologies and enabling reliable studies in fundamental oncology and pharmacology. This review focuses on the ability of ToC models to reproduce the tumor microenvironment, discusses the advantages and drawbacks of existing models and architectures, and explores the current materials and micro/nanofabrication techniques used to manufacture reliable and reproducible microfluidic ToC models.
ADVANCED MATERIALS
(2023)
Article
Optics
Vassily Kornienko, David Andersson, Mehdi Stiti, Jonas Ravelid, Simon Ek, Andreas Ehn, Edouard Berrocal, Elias Kristensson
Summary: In this paper, the authors propose a novel solution to the problem of time and spatial resolution in monitoring fast transient events. By combining multiplexed imaging with high-speed sensor technology, they are able to capture high-quality image series at two simultaneous time scales, enabling the tracking of rapidly evolving structures and the extraction of acceleration fields.
PHOTONICS RESEARCH
(2022)
Article
Geochemistry & Geophysics
Christopher J. M. Lawley, Andrew M. Somers, Bruce A. Kjarsgaard
Summary: Geochemical imaging using handheld LIBS is a rapid and qualitative method to unravel the complex geological histories of rocks and minerals without the need for extensive sample preparation. This approach enables mapping of variably altered mantle xenolith samples with cm-scale geochemical images in the field, demonstrating the sensitivity for detecting low concentrations of light elements such as Li and Na.
JOURNAL OF GEOCHEMICAL EXPLORATION
(2021)
Article
Computer Science, Information Systems
Lin-Tao Duan, Zhi-Guo Wang, Hai-Ying Wang
Summary: This study introduces an energy efficiency algorithm MWGE for tasks with time and precedence constraints, which adjusts processor speed to achieve maximum efficiency. Compared to the greedy algorithm, MWGE significantly reduces the speed switching rate and increases energy efficiency.
CLUSTER COMPUTING-THE JOURNAL OF NETWORKS SOFTWARE TOOLS AND APPLICATIONS
(2022)
Article
Optics
Wei Zhang, Xue Dong, Zhiwei Sun, Bo Zhou, Zhenkan Wang, Mattias Richter
Summary: This study presents a computational imaging approach using convolutional neural networks for interpolating CH2O PLIF images, achieving higher temporal resolution for visualizing intermediate species in combustion. Results demonstrate the model's ability to accurately predict PLIF images at various axial positions, serving as an efficient offline model to overcome challenges in ultra-high speed PLIF techniques.
Article
Chemistry, Analytical
Olatz Iparraguirre, Aiert Amundarain, Alfonso Brazalez, Diego Borro
Summary: European road safety has improved, but has not yet reached the European Commission's targets. C-ITS is expected to enhance road safety and traffic efficiency. This paper presents vision-based applications for traffic sign recognition and real-time weather alerts.
Review
Oncology
Reona Sakemura, Ismail Can, Elizabeth L. Siegler, Saad S. Kenderian
Summary: Visualizing the expansion and trafficking of CART cells in patients can help detect inadequate responses and toxicities early, guiding tailored treatment for maximum benefit. Various imaging platforms are being developed for this purpose, with many showing promise in providing valuable information and improving CART cell therapy.
MOLECULAR THERAPY-ONCOLYTICS
(2021)
Article
Multidisciplinary Sciences
Pengcheng Zhang, David Rumschitzki, Robert H. Edwards
Summary: This study investigates the release of secretory vesicles in mouse adrenal chromaffin cells and discovers diverse modes of release. Through comprehensive analysis, it is revealed that the variations in release cannot be solely explained by stochasticity, but involve distinct mechanisms. Furthermore, the loss of calcium sensor synaptotagmin 7 increases the proportion of slow events without altering the intrinsic properties of either class, suggesting the potential for independent regulation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Biotechnology & Applied Microbiology
Ahmed Refaat, May Lin Yap, Geoffrey Pietersz, Aidan Patrick Garing Walsh, Johannes Zeller, Blanca del Rosal, Xiaowei Wang, Karlheinz Peter
Summary: Advances in diagnostic imaging, particularly in the field of in vivo fluorescence imaging, provides valuable tools for early disease detection and investigation of disease mechanisms. However, the limited tissue penetration depth is a major challenge for its clinical application.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Pharmacology & Pharmacy
Amr Seifelnasr, Mohamed Talaat, Pranav Ramaswamy, Xiuhua April Si, Jinxiang Xi
Summary: This study aimed to develop a new delivery protocol to effectively deliver sprays to the posterior nose for mucosal immunization. By using high-speed imaging and 3D-printed transparent nasal casts, the spray deposition and subsequent liquid film formation and translocation were characterized. The optimal release angles for unidirectional and bidirectional delivery to the posterior nose were found to be 40 degrees and 30 degrees, respectively. The study also demonstrated that a supine position and dual-dose application significantly improved delivery to the nasopharynx.
Article
Materials Science, Multidisciplinary
Yael Gutierrez, Maria Losurdo, Iris Prinz, Adrian Prinz, Georg Bauer, Maria Bauer, Martina M. Schmidt, Thorsten Schaller
Summary: This paper demonstrates the design and industrial manufacturing process of reliable and cost-effective disposable SERS microfluidic chips using high throughput technologies. These chips exhibit high SERS enhancement and stability, making them suitable for customizable and cost-effective disposable point-of-care diagnostic applications.
ADVANCED ENGINEERING MATERIALS
(2022)
Article
Computer Science, Information Systems
Pablo Caballero, Guadalupe Ortiz, Alfonso Garcia-de-Prado, Juan Boubeta-Puig
Summary: This paper presents a context-aware and collaborative software architecture implemented in the field of e-health for seasonal allergies. The application processes user symptoms in real time and benefits from citizen collaboration to enhance user experience and utility.
MULTIMEDIA TOOLS AND APPLICATIONS
(2021)
Article
Spectroscopy
Qicheng Wu, Cesar Marina-Montes, Jorge O. Caceres, Jesus Anzano, Vincent Motto-Ros, Ludovic Duponchel
Summary: With the increasing availability of larger spectroscopic imaging data sets on complex samples, it becomes important to accurately detect and locate minor compounds and traces. However, current chemometric tools may not be completely suitable for such data sets due to their limited signal to noise ratio. This study presents a new approach called Interesting Features Finder (IFF) that is able to retrieve minor compounds and traces independently of the variance they may express in the data set, showing its potential in terms of sensitivity and robustness against noise.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2022)
Article
Engineering, Mechanical
Tenshiro Ichimura, Chihiro Inoue, Zhenying Wang, George Kuwabara, Kenji Tahara
Summary: This paper presents a method using a high-speed streaming camera and in-house image processing for real-time particle tracking velocimetry (PTV) above 1 kHz. The system is evaluated by measuring the diameter and velocity of multiple droplets. Two existing particle tracking methods, median flow (MF) and four-frame best estimate (4BE), are examined. The results show that with area-limiting processing, the proposed AMF and A4BE methods achieve faster processing times than MF, and 4BE and A4BE can even achieve 10 kHz with smaller image sizes.
FLOW MEASUREMENT AND INSTRUMENTATION
(2023)
Article
Construction & Building Technology
Sheng Zeng, Chenlong Zhang, Kun Zeng, Naixing Liang, Shubin Song
Summary: This study develops a real-time asphalt mixture segregation identification algorithm based on digital imaging technique and the static moment method. The algorithm calculates the static moments of aggregate particles relative to the four boundaries of the image and quantifies the degree of segregation by calculating the dispersion coefficient between the static moment of segregated asphalt mixture and the value of uniform asphalt mixture. The algorithm is applied in a field construction project in Yunnan, China, and it is shown to be capable of detecting and accurately identifying the degree of segregation of an asphalt mixture in real-time, surpassing the accuracy of the sand patch test in areas with uniform gradation but non-uniform distribution of aggregate particles.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Spectroscopy
Kheireddine Rifai, Marcel Laflamme, Marc Constantin, Francois Vidal, Mohamad Sabsabi, Alain Blouin, Paul Bouchard, Konstantinos Fytas, Maryline Castello, Blandine Nguegang Kamwa
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2017)
Article
Chemistry, Analytical
Hakim Loudyi, Kheireddine Rifai, Stephane Laville, Francois Vidal, Mohamed Chaker, Mohamad Sabsabi
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2009)
Article
Chemistry, Analytical
Kheireddine Rifai, Stephane Laville, Francois Vidal, Mohamad Sabsabi, Mohamed Chaker
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2012)
Article
Chemistry, Analytical
Kheireddine Rifai, Francois Vidal, Mohamed Chaker, Mohamad Sabsabi
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2013)
Article
Optics
F. Vidal, S. Laville, C. Goueguel, H. Loudyi, K. Rifai, M. Chaker, M. Sabsabi
JOURNAL OF QUANTITATIVE SPECTROSCOPY & RADIATIVE TRANSFER
(2010)
Article
Geochemistry & Geophysics
Nessrine Mohamed, Kheireddine Rifai, Samira Selmani, Marc Constantin, Francois R. Doucet, Lutfu C. Ozcan, Mohamad Sabsabi, Francois Vidal
Summary: The emerging fast laser-induced breakdown spectroscopy (LIBS) technique shows great potential for mineral exploration, providing direct, fast, and high-resolution mapping of chemical and mineral composition. LIBS has the advantages of faster speed and greater sensitivity to trace elements (e.g., Pd) and low atomic number elements.
GEOSTANDARDS AND GEOANALYTICAL RESEARCH
(2021)
Article
Physics, Fluids & Plasmas
K. Rifai, F. Vidal, T. W. Johnston
PHYSICS OF PLASMAS
(2007)
Article
Spectroscopy
Piyali Deb Barman, Ashok Kumar Maurya, Subhendu Ghosh, Ankit Roy, Mukul Madaan
Summary: In X-ray spectroscopic studies, K beta 1,3 lines have been used to examine the chemical states of 3d transition metals, but are not suitable for characterizing iron oxides. Instead, FeL-lines, which involve the valence shell 3d electrons, were inspected and found to provide information on the chemical states of iron. The study established a linear relationship between the chemical shift of FeL beta 1 line and spin multiplicity, allowing for the speciation of iron.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2024)
