Review
Nutrition & Dietetics
Ligia J. Dominguez, Nicola Veronese, Laura Vernuccio, Giuseppina Catanese, Flora Inzerillo, Giuseppe Salemi, Mario Barbagallo
Summary: A combination of factors contribute to cognitive decline, with age being the main independent risk factor. Prevention of cognitive decline and dementia emphasizes the crucial role of diet, physical activity, and lifestyle factors.
Article
Nutrition & Dietetics
Armando Pena, Micah L. Olson, Stephanie L. Ayers, Dorothy D. Sears, Sonia Vega-Lopez, Abigail T. Colburn, Gabriel Q. Shaibi
Summary: Obesity is linked to chronic inflammation and may increase the risk of type 2 diabetes in youth. This study investigated the relationship between inflammatory biomarkers and insulin sensitivity, beta-cell function, and response to lifestyle intervention in Latino youth with obesity. The findings showed that obesity-related inflammatory mediators were associated with T2D risk factors but were not affected by lifestyle intervention in Latino youth.
Article
Obstetrics & Gynecology
Alice Newman-Sanders, Jackson C. Kirkman-Brown, Meurig T. Gallagher
Summary: This study revealed a significant lack of awareness among young adults in the UK regarding the potential impacts of gym lifestyles and supplementation on male infertility. Men were found to have a concerning lack of concern for their own fertility, with differences in awareness levels between men and women. It was also observed that men were more likely to consider making changes to their behavior if it had a long-term impact on their fertility compared to short-term effects.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Review
Andrology
Aram Minas, Ana Carolina Cardillo Fernandes, Valter Luiz Maciel Junior, Luana Adami, Paula Intasqui, Ricardo Pimenta Bertolla
Summary: This literature review discusses the effects of exercise on male-related infertility. Moderate exercise can improve lifestyle-induced infertility, but excessive exercise may lead to infertility. The volume, intensity and duration of exercise are closely related to male fertility.
Review
Environmental Sciences
Adrianna Zanko, Katarzyna Siewko, Adam Jacek Kretowski, Robert Milewski
Summary: Infertility is a complex issue affecting millions of couples worldwide. Male infertility can be caused by various factors, including mechanical issues and abnormal sperm production. Semen quality is influenced by lifestyle factors, including diet, physical activity, sleep quality, and stress, which are also related to insulin resistance. To understand the connections between lifestyle, insulin resistance, and semen quality, a review of literature from 1989 to 2020 was conducted. Further research is recommended to explore the relationship between insulin resistance and semen quality by comparing men with and without insulin resistance.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Anesthesiology
Anne-Priscille Trouvin, Nadine Attal, Serge Perrot
Summary: It is important to analyze the lifestyle factors in patients with chronic pain without stigmatization. Some lifestyle factors, such as alcohol consumption, smoking, cannabis use, or psychostimulant intake, are harmful to patients, while physical activity and a balanced diet are considered beneficial, but require effort on the part of patients.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Physiology
Fabio Sarto, Martina Pizzichemi, Francesco Chiossi, Patrizia S. Bisiacchi, Martino Franchi, Marco Narici, Elena Monti, Antonio Paoli, Giuseppe Marcolin
Summary: This study investigated the effects of a physically active lifestyle on static and dynamic postural balance control (PBC) in young and older adults. The results showed that physically active young adults had higher efficiency in maintaining PBC compared to other groups, and dynamic PBC assessment was more sensitive in detecting differences between groups.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Nutrition & Dietetics
Sharlize Pedroza Matute, Sasitaran Iyavoo
Summary: The gut microbiota is closely related to the health and disease state of the human body, and can be influenced by factors such as diet, exercise, and mental health. Understanding the impact of lifestyle on the gut microbiota can lead to personalized advice for preventing and improving dysbiosis. However, providing effective advice relies on accurate research and assessment methods.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Monika Siegrist, Melanie Heitkamp, Isabell Braun, Nicolas Vogg, Bernhard Haller, Helmut Langhof, Wolfgang Koenig, Martin Halle
Summary: The study found that short-term lifestyle interventions have significant effects on the body weight, adipokines, and cardiometabolic risk parameters in children with obesity. The improvements in BMI and BMI-SDS persisted over one year of follow-up.
CLINICAL NUTRITION
(2021)
Review
Biochemistry & Molecular Biology
Maria Nunzia De Luca, Marisa Colone, Riccardo Gambioli, Annarita Stringaro, Vittorio Unfer
Summary: Infertility is a global health problem affecting approximately 187 million couples worldwide, with oxidative stress being a common reason for male infertility. Antioxidant supplementation is considered effective in improving male fertility parameters due to their synergistic effects in decreasing ROS concentration. Additionally, natural molecules such as myo-inositol and d-chiro-inositol play a role in ameliorating sperm quality by regulating various cellular mechanisms.
Review
Oncology
Sara P. Lester, Aparna S. Kaur, Suneela Vegunta
Summary: This review examines emerging evidence for the association of modifiable factors on mammographic breast density (MBD) and the influence of MBD on breast cancer risk, recommending that patients be counseled on modifiable risk factors to tailor breast cancer prevention strategies.
Article
Nutrition & Dietetics
Thorsten Schmidt, Philip Suess, Dominik M. Schulte, Anne Letsch, Wiebke Jensen
Summary: The diagnosis and treatment of cancer can cause physical and psychological impairment, and side effects may limit treatment effectiveness. However, studies have shown that physical activity and exercise therapy are feasible and recommended for cancer patients. Additionally, combining nutrition therapy and physical activity can prevent and reduce treatment-related side effects. Evidence-based recommendations for cancer prevention through nutrition therapy and exercise should be integrated into treatment plans and healthcare services.
Article
Public, Environmental & Occupational Health
Hanran Mai, Junyi Ke, Zilin Zheng, Jieyi Luo, Miaomiao Li, Yanxia Qu, Fan Jiang, Simian Cai, Liandong Zuo
Summary: This study found that smoking and drinking, consumption of sweet foods, dietary habits, sleep duration, and intake of milk, roughage, and eggs are associated with semen quality.
REPRODUCTIVE HEALTH
(2023)
Review
Medicine, General & Internal
Ashok Agarwal, Saradha Baskaran, Neel Parekh, Chak-Lam Cho, Ralf Henkel, Sarah Vij, Mohamed Arafa, Manesh Kumar Panner Selvam, Rupin Shah
Summary: Infertility affects 8-12% of couples globally, with male factors contributing to around 50%. The causes of male infertility are diverse, requiring thorough evaluation to identify treatable or reversible factors. Semen analysis is key for evaluation, while advanced tests have been developed to investigate sperm quality and function.
Review
Andrology
Federico Belladelli, Satvir Basran, Michael L. Eisenberg
Summary: According to existing studies, sedentary behavior contributes to male infertility, and the relationship between physical activity (PA) and male infertility, semen characteristics, and pregnancy rates is complex. While some forms of physical activity showed improvements in pregnancy rates, others did not consistently improve semen quality. More intense exercise and certain types of exercise may even impair male fertility. Further research, particularly randomized trials, is necessary to investigate the specific effects of different forms of exercise on semen parameters and reproductive outcomes.
WORLD JOURNAL OF MENS HEALTH
(2023)
Review
Sport Sciences
Luigi Di Luigi, Emanuela A. Greco, Chiara Fossati, Antonio Aversa, Paolo Sgro, Cristina Antinozzi
Summary: Various endogenous and exogenous variables affect the hormone levels and sports performance in female athletes, and differences in sex chromosome abnormalities contribute to biological, functional, and hormonal variations among athletes. Physicians need to be aware of and understand the hormone variability and related health concerns in order to support healthy, fair, and inclusive sports participation for female athletes.
INTERNATIONAL JOURNAL OF SPORTS MEDICINE
(2023)
Article
Social Sciences, Interdisciplinary
Maria Grazia Vaccaro, Giulia Izzo, Alessia Sarica, Sandro La Vignera, Antonio Aversa
Summary: This study aims to analyze the different perceptions of sociosexual experiences among the southern population during the COVID-19 pandemic. Through cluster analysis, we identified eleven clusters and found intra- and inter-diagnostic heterogeneity in the sexual profile of participants. We also discovered significant gender differences, with women showing a greater propensity for positive sexual attitudes and desires compared to men.
SEXUALITY RESEARCH AND SOCIAL POLICY
(2023)
Article
Sport Sciences
Fabrizio Perroni, Ludovica Cardinali, Lamberto Cignitti, Stefano Amatori, Marco B. L. Rocchi, Vilberto Stocchi, Giovanni Piccoli, Carlo Baldari, Davide Sisti, Laura Guidetti, Mario Vetrano, Sveva M. Nusca
Summary: This study analyzed the body composition of Italian firefighters and found that poor body composition may increase the risk of cardiac events and reduce functional capacity. The study also found that fitness values could predict muscle quality in firefighters, which is important for promoting a healthy lifestyle among firefighters.
SPORT SCIENCES FOR HEALTH
(2023)
Article
Environmental Sciences
Fioretta Silvestri, Matteo Campanella, Maurizio Bertollo, Maicon Rodrigues Albuquerque, Valerio Bonavolonta, Fabrizio Perroni, Carlo Baldari, Laura Guidetti, Davide Curzi
Summary: This study investigated whether a massed basketball training program enriched with Fitlight training can improve executive function (EF) and motor performance. The results showed that three weeks of massed basketball training improved EF and motor performance in young players. The additional Fitlight training increased perceived cognitive effort, but did not further improve EF.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Genetics & Heredity
Maria Carmela Zagari, Paola Chiarello, Stefano Iuliano, Lucia D'Antona, Valentina Rocca, Emma Colao, Nicola Perrotti, Francesca Greco, Rodolfo Iuliano, Antonio Aversa
Summary: Loss of function mutations in the PHEX gene can lead to X-linked dominant hypophosphatemia, the most common form of genetic rickets. This condition is characterized by renal phosphate wasting, increased fibroblast growth factor 23 (FGF-23), growth retardation, bone deformities, and musculoskeletal manifestations. Despite the discovery of numerous mutations in the PHEX gene, there are currently no clear genotype-phenotype correlations in patients with hypophosphatemic rickets (XLH).
Article
Medicine, General & Internal
Sandro La Vignera, Rosita A. Condorelli, Aldo E. Calogero, Rossella Cannarella, Antonio Aversa
Summary: This study prospectively investigates the effects of liraglutide, a GLP1 analog, on reproductive and sexual function in men with metabolic hypogonadism. The results show that liraglutide significantly improves sperm parameters and erectile function, as well as increasing testosterone and sex hormone-binding globulin levels. This suggests that liraglutide is a useful pharmacological treatment for male patients with metabolic hypogonadism.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Sport Sciences
Fabrizio Perroni, Carlo Castagna, Stefano Amatori, Erica Gobbi, Mario Vetrano, Vincenzo Visco, Laura Guidetti, Carlo Baldari, Marco Bruno Luigi Rocchi, Davide Sisti
Summary: This study used exploratory factor analysis to assess the fitness performance of youth football players. The results showed that physical performance, training status, and anthropometric characteristics are important factors in evaluating youth football players.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2023)
Article
Medicine, General & Internal
Andrea Crafa, Aldo Eugenio Calogero, Rossella Cannarella, Rosita Angela Condorelli, Antonio Aversa, Sandro La Vignera
Summary: Male infertility and prostate cancer are the most researched andrological diseases, followed by benign prostatic hyperplasia and erectile dysfunction, which are expected to increase in prevalence due to population aging. However, research on inflammation of the accessory sexual glands is relatively scarce.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Livia Basile, Rosita A. Condorelli, Aldo E. Calogero, Rossella Cannarella, Federica Barbagallo, Andrea Crafa, Antonio Aversa, Sandro La Vignera
Summary: Red wine is rich in nutrients and has been the focus of numerous scientific studies. It has been reported that moderate consumption of red wine, with its phenolic and antioxidant properties, can have positive effects on various diseases. Additionally, the ethanol content in red wine has shown various biological properties. However, little is known about the correlation between red wine consumption and male sexual function. This review aimed to evaluate the effects of moderate red wine consumption on erectile function and found potential benefits in patients with erectile dysfunction as well as positive influences on reproductive function through vasorelaxant and antioxidant mechanisms.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pharmacology & Pharmacy
Rossella Cannarella, Cristina M. B. Petralia, Rosita A. Condorelli, Antonio Aversa, Aldo E. Calogero, Sandro La Vignera
Summary: This article provides an overview of the molecular mechanisms and usage of follicle-stimulating hormone (FSH) in the treatment of male infertility. It also evaluates the predictor factors of FSH administration response and the indications of the latest guidelines on the use of FSH in male infertility treatment.
EXPERT OPINION ON INVESTIGATIONAL DRUGS
(2023)
Review
Endocrinology & Metabolism
Cristina Antinozzi, Emanuela A. Greco, Paolo Sgro, Ivan Dimauro, Antonio Aversa, Luigi Di Luigi
Summary: In addition to its mechanical roles, the skeletal muscle system plays a crucial role in thermoregulation, secondary sexual characteristics, hormone metabolism, glucose uptake and storage, and energetic metabolism. PDE5i drugs, such as tadalafil, can influence skeletal muscle physiology and endocrine-metabolic pathways by increasing the intracellular level of cGMP. These drugs can modulate insulin-related metabolic pathways and hormone responses, protein metabolism, and anabolism/catabolism during and after physical exercise-related stress.
MINERVA ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Walter Vena, Liborio Vaccalluzzo, Sandro La Vignera, Emanuela Morenghi, Cristina D'Agostino, Anna Perri, Bruno Giammusso, Andrea G. Lania, Antonio Aversa, Alessandro Pizzocaro
Summary: This study aimed to evaluate the improvement of penile vascular flows after LISWT treatment in patients with ED. The results showed that LISWT improved erectile hardness and satisfaction rates among patients with ED.
MINERVA ENDOCRINOLOGY
(2023)
Review
Rheumatology
Maria Chiara Massari, Viviana Maria Bimonte, Lavinia Falcioni, Antimo Moretti, Carlo Baldari, Giovanni Iolascon, Silvia Migliaccio
Summary: 'Frailty' is a state of increased vulnerability caused by impairment of homeostasis due to stress. Frail individuals are more likely to experience significant health decline and have a higher risk of adverse outcomes such as osteoporosis, falls, and disability. Frailty is becoming increasingly important due to global population aging. The pathophysiology of frailty involves cumulative molecular and cellular damage and is partially independent of aging but closely related. Uncorrected nutrition and sedentary behavior worsen frailty.
THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE
(2023)
Review
Nutrition & Dietetics
Vincenzo Garofalo, Rosita A. Condorelli, Rossella Cannarella, Antonio Aversa, Aldo E. Calogero, Sandro La Vignera
Summary: This systematic review and meta-analysis examines the relationship between iron deficiency and thyroid function. The analysis reveals that patients with iron deficiency have lower thyroid hormone levels, especially in pregnant women. It also shows that iron deficiency increases the prevalence of thyroid autoantibodies.
Article
Endocrinology & Metabolism
Stefano Iuliano, Francesca Greco, Giuseppe Seminara, Maria C. Zagari, Paolo Sgro, Gianfranco Di Gennaro, Emanuela A. Greco, Antonio Aversa
Summary: This study suggests that the combination of unsupervised physical activity and a nutraceutical supplement can improve body composition, insulin sensitivity, and testosterone production in overweight-obese men with subclinical hypogonadism. Further long-term controlled studies are necessary to elucidate the potential impact on fertility.
MINERVA ENDOCRINOLOGY
(2023)
