Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma

Abstract 4957: The novel imipridone ONC212 highly synergizes with the BCL-2 inhibitor ABT-199 in AML and activates orphan receptor GPR132

(2018) Takenobu Nii et al.   CANCER RESEARCH

Integrated genomic characterization of oesophageal carcinoma

(2017)   NATURE

Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma

(2016) Lutz Krause et al.   CARCINOGENESIS

Role of interleukin-6 in cancer progression and therapeutic resistance

(2016) Neeraj Kumari et al.   TUMOR BIOLOGY

Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition

(2015) Hong Liu et al.   CARCINOGENESIS

Epidemiology, Diagnosis, and Management of Esophageal Adenocarcinoma

(2015) Joel H. Rubenstein et al.   GASTROENTEROLOGY

Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

(2015) Timothy J Underwood et al.   JOURNAL OF PATHOLOGY

Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial

(2015) Joel Shapiro et al.   LANCET ONCOLOGY

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Oesophageal carcinoma

(2013) Arjun Pennathur et al.   LANCET

Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines

(2013) Cleidson Pádua Alves et al.   STEM CELLS

DNA damage induces the IL-6/STAT3 signaling pathway, which has anti-senescence and growth-promoting functions in human tumors

(2012) Un Jung Yun et al.   CANCER LETTERS

Abstract 5317: Non-invasive dynamic bioluminescence imaging of tumor functional vascular changes during antiangiogenic therapy in conscious mice

(2012) Christian R. Schnell et al.   CANCER RESEARCH

Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus

(2012) Sebastian F. Schoppmann et al.   CLINICAL & EXPERIMENTAL METASTASIS

A global assessment of the oesophageal adenocarcinoma epidemic

(2012) Gustaf Edgren et al.   GUT

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

(2012) Keun Hur et al.   GUT

Unlike Pancreatic Cancer Cells Pancreatic Cancer Associated Fibroblasts Display Minimal Gene Induction after 5-Aza-2′-Deoxycytidine

(2012) Jun Yu et al.   PLoS One

IL-6 Promotes Head and Neck Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition via the JAK-STAT3-SNAIL Signaling Pathway

(2011) A. Yadav et al.   MOLECULAR CANCER RESEARCH

Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers

(2010) A. Saadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Microenvironmental regulation of cancer development

(2008) Min Hu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT