Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

Sensing of Cytoskeletal Forces by Asymmetric Adherens Junctions

(2018) Tsveta S. Malinova et al.   TRENDS IN CELL BIOLOGY

Identification of novel PIEZO1 variants using prenatal exome sequencing and correlation to ultrasound and autopsy findings of recurrent hydrops fetalis

(2018) Ilina Datkhaeva et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves

(2016) Boksik Cha et al.   GENES & DEVELOPMENT

CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity

(2016) Patrick L. Crosswhite et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Piezo2 senses airway stretch and mediates lung inflation-induced apnoea

(2016) Keiko Nonomura et al.   NATURE

The Role of PIEZO2 in Human Mechanosensation

(2016) Alexander T. Chesler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

(2016) Wei-Chien Hung et al.   Cell Reports

Piezo1 Channels Are Inherently Mechanosensitive

(2016) Ruhma Syeda et al.   Cell Reports

Disorders of erythrocyte volume homeostasis

(2015) E. Glogowska et al.   International Journal of Laboratory Hematology

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

(2015) Amélie Sabine et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymph flow regulates collecting lymphatic vessel maturation in vivo

(2015) Daniel T. Sweet et al.   JOURNAL OF CLINICAL INVESTIGATION

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

Mechanically Activated Ion Channels

(2015) Sanjeev S. Ranade et al.   NEURON

Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

(2015) Viktor Lukacs et al.   Nature Communications

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

(2015) Elisavet Fotiou et al.   Nature Communications

Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling

(2015) Kevin Retailleau et al.   Cell Reports

Ventromedial hypothalamic neurons control a defensive emotion state

(2015) Prabhat S Kunwar et al.   eLife

Piezo1 links mechanical forces to red blood cell volume

(2015) Stuart M Cahalan et al.   eLife

F-Actin–Anchored Focal Adhesions Distinguish Endothelial Phenotypes of Human Arteries and Veins

(2014) Daphne van Geemen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Notch signaling functions in lymphatic valve formation

(2014) A. Murtomaki et al.   DEVELOPMENT

Functional Role for Piezo1 in Stretch-evoked Ca2+Influx and ATP Release in Urothelial Cell Cultures

(2014) Tatsuya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lymphatic collecting vessel maturation and valve morphogenesis

(2014) Daniel Vittet   MICROVASCULAR RESEARCH

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature

(2013) K. Koltowska et al.   DEVELOPMENT

Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis

(2013) Florence Tatin et al.   DEVELOPMENTAL CELL

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Lymphatic vascular morphogenesis in development, physiology, and disease

(2011) Stefan Schulte-Merker et al.   JOURNAL OF CELL BIOLOGY

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Molecular Biology and Pathology of Lymphangiogenesis

(2008) Terhi Karpanen et al.   Annual Review of Pathology-Mechanisms of Disease