期刊
ACTA CIRURGICA BRASILEIRA
卷 31, 期 3, 页码 206-211出版社
ACTA CIRURGICA BRASILEIRA
DOI: 10.1590/S0102-865020160030000009
关键词
Drug Resistance; Microbial; Polymerase Chain Reaction; Genotyping Techniques; Pseudomonas aeruginosa
类别
资金
- Ahvaz Jundishapur University of Medical Sciences [91132]
PURPOSE: To determine the genetic diversity of MDR P. aeruginosa strains isolated from burn and wound infections in Ahvaz, Iran, by ERIC-PCR. METHODS: From total 99 strains of P. aeruginosa defined as MDR by using drug susceptibility testing, 66 were subjected to ERIC-PCR analysis, comprises 53 strains isolated from burn infection, and 13 randomly selected strains from wound infection with higher resistance to combinations of more numbers of drugs. RESULTS: Eight clusters (I to VIII), and 50 single clones were generated for tested MDR isolates analyzed by ERIC-PCR. The high heterogeneity was observed among the isolates from burn infections including 16 isolates which were categorized in eight clusters and 37 single clones. The isolates in clusters II, III, VI, VIII showed 100% similarity. CONCLUSIONS: The high level of genotypic heterogeneity in P. aeruginosa strains demonstrated no genetic correlation between them. Extremely high drug resistance in isolates from burn, suggests that efficient control measures and proper antibiotic policy should be observed.
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