Article
Obstetrics & Gynecology
Anna Akselsson, Jenny Rossen, Elisabeth Storck-Lindholm, Ingela Radestad
Summary: This study investigated the relationship between sociodemographic and obstetric factors and Body Mass Index (BMI) classifications in pregnant women, and examined the association between BMI classifications and stillbirth and other pregnancy outcomes. The results showed that women who were overweight, obese, or severely obese were more likely to experience adverse pregnancy outcomes such as stillbirth and transfer to neonatal care. National guidelines and individualized care are needed to prevent and reduce negative pregnancy outcomes in overweight or obese women.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Nutrition & Dietetics
Miriam Oros, Julia Siscart, Daniel Perejon, Maria Catalina Serna, Pere Godoy, Blanca Salinas-Roca
Summary: This study examines the prevalence of overweight and obesity in pregnant women from different ethnic groups and investigates the associated comorbidities. The results show an increasing trend in obesity among pregnant women, with a higher incidence of overweight and obesity in certain ethnic groups. High body mass index (BMI) is found to be associated with hypertension, gestational diabetes mellitus, and depression.
Article
Medicine, General & Internal
Xiuling Zhao, Shi Wu Wen, Wei Ma, Pili Xu, Chunmei Zhang, Shan Jiang, Laura M. M. Gaudet, Jie Gao
Summary: This study explores the feasibility and usability of using resting energy expenditure (REE) to guide gestational weight gain (GWG) management in obese and overweight women. The findings suggest that using REE can significantly reduce daily total energy intake, overall GWG, and the percentage of excess-GWG.
Article
Pediatrics
Torill Alise Rotevatn, Rikke Normark Mortensen, Line Rosenkilde Ullits, Christian Torp-Pedersen, Charlotte Overgaard, Anna Marie Balling Hostgaard, Henrik Boggild
Summary: This study compared the predictive performance of models based on predictors available at birth with and without information on infant weight gain in the first year for childhood obesity risk prediction. The results showed that adding information on infant weight gain improved the model's discrimination, reclassification, and sensitivity.
Article
Obstetrics & Gynecology
H. Valgeirsdottir, T. Kunovac Kallak, I. Sundstrom Poromaa, M. Jonsson, N. Roos, L. Lindstrom, A-K Wikstrom
Summary: A nationwide register-based cohort study in Sweden found that women with polycystic ovary syndrome (PCOS) have an increased risk of stillbirth, particularly in late pregnancy. Compared to women without PCOS, women with PCOS had a 50% higher risk of stillbirth. However, women with PCOS and a severe hyperandrogenic profile did not show a stronger association with stillbirth compared to those without this profile.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Eliezer Dade, Miranda Metz, Jean Lookens Pierre, Vanessa Rouzier, Rodney Sufra, Elizabeth Fox, Fabyola Preval, Stephano St-Preux, Jean Ronald Zephir II, Wilson Ariste, Rehana Rasul, Shalom Sabwa, Nicholas Roberts, Marie Marcelle Deschamps, Patrice Severe, Daniel Fitzgerald, Jean William Pape, Lily Du Yan, Margaret L. McNairy
Summary: This study describes BMI and waist circumference (WC) and factors associated with obesity in Haiti. The findings show that women in Haiti have a significantly higher prevalence of obesity compared to men, and abdominal obesity is also common. Haiti faces the dual challenges of food insecurity and an obesity epidemic.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Tsung-Po Chen, Hui-Chieh Yu, Tai-Hsin Lin, Yu-Hsun Wang, Yu-Chao Chang
Summary: This population-based cohort study in Taiwan found an association between obesity and the development of chronic periodontitis (CP), with obese patients having a 1.12-fold increased risk of CP compared to non-obese patients. The risk was higher in patients aged 65 or older. Differences in CP risk between obesity and non-obesity groups were not observed by sex.
Review
Endocrinology & Metabolism
Zoe L. Reichental, Victoria M. O'Brien, Sharleen L. O'Reilly
Summary: This review evaluates breastfeeding interventions for at-risk populations, finding that such interventions can improve exclusive early postpartum breastfeeding and any breastfeeding at 6 months in women with gestational diabetes or obesity/overweight. Further randomized controlled trials are needed to confirm efficacy and harmonize breastfeeding outcome reporting.
Article
Rheumatology
Andrea Dell'Isola, Kenneth Pihl, Aleksandra Turkiewicz, Velocity Hughes, Weiya Zhang, Sita Bierma-Zeinstra, Daniel Prieto-Alhambra, Martin Englund
Summary: This study found that incident knee and hip osteoarthritis patients had an increased risk of depression, cardiovascular diseases, back pain, osteoporosis, and diabetes mellitus, with diabetes mellitus risk only found in knee osteoarthritis.
ARTHRITIS CARE & RESEARCH
(2022)
Article
Nutrition & Dietetics
Hannah Oh, So-Young Kwak, Garam Jo, Juhee Lee, Dahyun Park, Dong Hoon Lee, NaNa Keum, Jong-Tae Lee, Edward L. Giovannucci, Min-Jeong Shin
Summary: The study examined the relationships between BMI, waist circumference, predicted body fat mass, and mortality in a Korean population. The results showed a J-shaped association between BMI and all-cause and cardiovascular mortality, with the lowest point at BMI = 25.0-29.9. It was also found that higher waist circumference and predicted body fat mass were positively associated with mortality, suggesting a need for re-evaluation of current overweight criteria for Asians.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Endocrinology & Metabolism
Helen R. Murphy, Carla Howgate, Jackie O'Keefe, Jenny Myers, Margery Morgan, Matthew A. Coleman, Matthew Jolly, Jonathan Valabhji, Eleanor M. Scott, Peter Knighton, Bob Young, Nick Lewis-Barned
Summary: The study aimed to compare modifiable risk factors associated with adverse pregnancy outcomes in women with type 1 and type 2 diabetes, and found that maternal glycaemia and BMI are key modifiable risk factors. There were no substantial differences in outcomes between maternity clinics.
LANCET DIABETES & ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Maria Hornstrup Christensen, Marianne Skovsager Andersen, Katrine Hass Rubin, Ellen Aagaard Nohr, Jori Aalders, Christina Anne Vinter, Dorte Moeller Jensen
Summary: This study investigated the association between previous gestational diabetes mellitus (GDM) and incident psychiatric morbidity, and explored the role of subsequent diabetes development in psychiatric morbidity risk. The findings indicated that GDM was associated with an increased risk of depression and anxiety disorders, and subsequent diabetes played a significant role in future psychiatric morbidity risk.
Article
Public, Environmental & Occupational Health
Wei Jie Gong, Daniel Yee Tak Fong, Man Ping Wang, Tai Hing Lam, Thomas Wai Hung Chung, Sai Yin Ho
Summary: This study examined the trajectories of overweight/obesity in Hong Kong Chinese children and their associations with self-esteem. The findings revealed that late-onset or chronic overweight/obesity predicted low self-esteem, particularly in the domains of general, social, and academic/school-related self-esteem. On the other hand, children in the early-onset overweight/obesity group showed no significant differences except for a lower risk of low social self-esteem.
Article
Public, Environmental & Occupational Health
D. Liu, J. Yang, S. Wang
Summary: The study found that early-life exposure to famine decreased the risk of overweight and abdominal obesity in adulthood, while exposure to famine during any childhood period reduced the risk of abdominal obesity. Exposure to famine in mid-childhood also decreased the risk of general obesity in both males and females.
Article
Obstetrics & Gynecology
Christiane Lundegaard Haas, Anette Varbo, Peter Norkjaer Laursen, Volker Schnecke, Adam H. Balen
Summary: This study examines the associations between baseline BMI and change in body weight with the likelihood of pregnancy in women with PCOS. The results show that higher baseline BMI is associated with a lower chance of pregnancy, while weight loss is associated with an increased chance of pregnancy. The findings suggest that weight loss is beneficial for overweight/obese women with PCOS who are seeking to become pregnant.
HUMAN REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Hanna Amark, Magnus Westgren, Martina Persson
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2019)
Article
Medicine, General & Internal
Neda Razaz, Sven Cnattingius, Martina Persson, Kristina Tedroff, Sarka Lisonkova, K. S. Joseph
Article
Pediatrics
Josephine Haas, Martina Persson, Eva Hagstrom Toft, Bjorn Rathsman, Anna-Lena Brorsson, Anna Lindholm Olinder
Article
Obstetrics & Gynecology
Helena Fadl, Maryam Saeedi, Scott Montgomery, Anders Magnuson, Erik Schwarcz, Kerstin Berntorp, Verena Sengpiel, Elisabeth Storck-Lindholm, Helena Strevens, Anna-Karin Wikstrom, Sophia Brismar-Wendel, Martina Persson, Stefan Jansson, Fredrik Ahlsson, Carina Ursing, Linda Ryen, Kerstin Petersson, Ulla-Britt Wennerholm, Karin Hilden, David Simmons
BMC PREGNANCY AND CHILDBIRTH
(2019)
Article
Medicine, General & Internal
Louise Lindberg, Emilia Hagman, Pernilla Danielsson, Claude Marcus, Martina Persson
Article
Medicine, General & Internal
Louise Lindberg, Pernilla Danielsson, Martina Persson, Claude Marcus, Emilia Hagman
Article
Obstetrics & Gynecology
Hanna Amark, Meeli Sirotkina, Magnus Westgren, Nikos Papadogiannakis, Martina Persson
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2020)
Article
Medicine, General & Internal
Martina Persson, Signe Opdahl, Kari Risnes, Raz Gross, Eero Kajantie, Abraham Reichenberg, Mika Gissler, Sven Sandin
Article
Multidisciplinary Sciences
Lue Ping Zhao, George K. Papadopoulos, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Daniel E. Geraghty, Ake Lernmark
Summary: Using deep learning of DQ residue sequences, critical residues and motifs associated with T1D were uncovered on HLA-DQ molecules, including susceptibility and resistance associations. These residues, located on alpha and beta chains, play significant roles in the risk and protection against T1D.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Lue Ping Zhao, George K. Papadopoulos, Terry P. Lybrand, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Stephen S. Rich, Ake Lernmark
Summary: The study identified three amino acid residues of HLA-DRB1 (beta 71, beta 74, beta 86) predictive of T1D risk, with the KAG motif being most strongly associated with increased risk. Other motifs were also found to be linked with T1D risk or protection.
Article
Pediatrics
Emma Hedlund, Johnny Ludvigsson, Helena Elding Larsson, Gun Forsander, Sten Ivarsson, Claude Marcus, Ulf Samuelsson, Martina Persson, Annelie Carlsson
Summary: This study used population-based data in Sweden to investigate the association between month of birth and incidence of type 1 diabetes. The results showed that there was no significant correlation between month of birth and the risk of type 1 diabetes in the entire cohort. However, boys diagnosed before the age of 5 were more likely to be born in May.
Article
Pediatrics
Weiyao Yin, Nora Doring, Monica S. M. Persson, Martina Persson, Kristina Tedroff, Ulrika Aden, Sven Sandin
Summary: The risk of intellectual disability increases weekly as the gestational age moves away from 40 weeks, and this association is consistent across different levels of ID severity.
ARCHIVES OF DISEASE IN CHILDHOOD
(2022)
Article
Medicine, General & Internal
Jenny Bolk, Eleni Simatou, Jonas Soderling, Lisa B. Thorell, Martina Persson, Helene Sundelin
Summary: This study suggests that children with pediatric ischemic stroke have an increased risk of ADHD, especially in those with adverse motor outcomes and/or epilepsy, compared to controls. The risk of ADHD increases after childhood strokes regardless of comorbidities.
Article
Public, Environmental & Occupational Health
Martina Persson, Abraham Reichenberg, Mikael Andersson Franko, Sven Sandin
Summary: This study suggests that maternal type 1 diabetes (T1D) may increase the risk of autism spectrum disorder (ASD) in offspring. It is found that this risk may be mediated by pre-term birth, which affects about one-third of pregnancies with T1D. Additionally, maternal levels of glycated haemoglobin (HbA1c) do not impact the risk of ASD beyond the T1D diagnosis itself.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Weiyao Yin, Jonas F. Ludvigsson, Ulrika Aden, Kari Risnes, Martina Persson, Abraham Reichenberg, Michael E. Silverman, Eero Kajantie, Sven Sandin
Summary: This study investigated the association between psychiatric diagnoses in fathers, mothers, and both parents and gestational age. The results showed that both paternal and maternal psychiatric diagnoses were associated with earlier gestational age, and the risk increased when both parents were diagnosed. The risk also increased when fathers and mothers were diagnosed with different psychiatric disorders. These findings suggest that the presence of psychiatric diagnoses in parents impacts gestational age at birth.