Article
Neurosciences
Lei Wang, Xiaodan Chen, Yuehua Xu, Miao Cao, Xuhong Liao, Yong He
Summary: The study discovered that functional hubs in the human brain network can be classified into three types (low-frequency, middle-frequency, and high-frequency) based on different frequency bands, with the hubs mainly distributed in regions such as the frontal lobe, parietal lobe, prefrontal cortex, temporal lobe, amygdala, and cerebellum.
NEUROSCIENCE BULLETIN
(2022)
Article
Neurosciences
Aman Taxali, Mike Angstadt, Saige Rutherford, Chandra Sripada
Summary: Recent studies have shown that the use of predictive models can improve the reliability of functional magnetic resonance imaging (fMRI), with the predicted outcomes of these models being more reliable than individual imaging features, reaching good levels of reliability for some methods.
Article
Neurosciences
Lan Yang, Jing Wei, Ying Li, Bin Wang, Hao Guo, Yanli Yang, Jie Xiang
Summary: This study examined the test-retest reliabilities of synchrony and metastability using data from the Human Connectome Project. The results showed good reliability for these indexes, with factors such as field strength and denoising affecting their values. The study provides methodological reference for exploring dynamic neural activity in the brain using synchrony and metastability in fMRI signals.
Article
Multidisciplinary Sciences
Yulin Wang, Wei Duan, Debo Dong, Lihong Ding, Xu Lei
Summary: Here, we provide a test-retest dataset of electroencephalogram (EEG) measurements obtained in various resting and cognitive states. The dataset includes short-term and long-term designs, allowing for the investigation of both intra- and inter-session variability in electrophysiological changes, as well as alterations in resting and cognitive states. Additionally, this dataset contributes to the reliability and validity of EEG measurements by providing an open resource.
Article
Psychology, Experimental
Cindy Eckart, Dominik Kraft, Christian J. Fiebach
Summary: Affective flexibility refers to the flexible adaptation of behavior or thought given emotionally relevant stimuli, and has been associated with emotion regulation efficiency. The study found that response time-based affective switch costs are a suitable measure for individual differences, with good internal consistency and test-retest reliability.
Article
Neurosciences
Shiori Amemiya, Hidemasa Takao, Yusuke Watanabe, Satoru Miyawaki, Satoshi Koizumi, Nobuhito Saito, Osamu Abe
Summary: This study examined the perfusion in patients with steno-occlusive disease using resting-state functional MRI (rsfMRI) and found that the time delay parameter of rsfMRI is more sensitive to hemodynamic changes compared to single-photon emission CT (SPECT) cerebral blood flow (CBF). However, the reliability of rsfMRI is lower than SPECT.
Article
Neurosciences
Faezeh Vedaei, Mahdi Alizadeh, Victor Romo, Feroze B. Mohamed, Chengyuan Wu
Summary: This study investigates the test-retest reliability of rs-fMRI in neuroscience, showing that reliability of measurements is higher under anesthesia and increases with longer scan lengths.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Peiying Liu, Gongkai Liu, Marco C. Pinho, Zixuan Lin, Binu P. Thomas, Melissa Rundle, Denise C. Park, Judy Huang, Babu G. Welch, Hanzhang Lu
Summary: The study optimized and evaluated a resting-state BOLD functional MRI technique to measure cerebrovascular reactivity and demonstrated its relationship to neurosurgical treatment. The results showed that the technique provided a task-free method to assess cerebrovascular reserve and depicted the treatment effect of revascularization surgery in patients with Moyamoya disease, comparable to the reference standard of CO2 inhalation MRI.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ajay Nemani, Mark J. Lowe
Summary: This study assessed the test-retest reliability of functional connectivity in different field strengths by scanning subjects at 3T and 7T. Results showed that the reliability of intrinsic networks was significantly greater at 7T compared to 3T, with the greatest improvement seen in intra-network reliability. The findings support the trend of migrating functional imaging studies to ultrahigh field strengths.
Article
Computer Science, Artificial Intelligence
Feifan Feng, Zhenglin Zhang, Lijuan Tang, Haisheng Qian, Li-Zhuang Yang, Haihe Jiang, Hai Li
Summary: Recent studies suggest the promise of automatic speech analysis for diagnosing movement and cognitive disorders, but research on the reliability of acoustic and linguistic measures is lacking. This study examines the test-retest reliability of commonly used features in healthy Chinese adults, finding differing levels of reliability among different features.
COMPUTER SPEECH AND LANGUAGE
(2023)
Article
Multidisciplinary Sciences
Catia M. Oliveira, Marianna E. Hayiou-Thomas, Lisa M. Henderson
Summary: The Serial Reaction Time task is widely used in individual differences research to examine the role of procedural memory. However, recent meta-analysis shows that the task has poor reliability, despite producing robust effects at the group level. Therefore, caution should be exercised when using the task for individual differences research until factors improving its reliability are better understood.
ROYAL SOCIETY OPEN SCIENCE
(2023)
Article
Neurosciences
Feng Xu, Dapeng Liu, Dan Zhu, Argye E. Hillis, Arnold Bakker, Anja Soldan, Marilyn S. Albert, Doris D. M. Lin, Qin Qin
Summary: This MRI study evaluated the test-retest reliability of VSI-prepared 3D VSASL protocol to measure baseline CBF variations in different brain regions among cognitively normal participants. The study found that both absolute and relative CBF showed higher variability, but could still detect normal variations using VSASL.
Article
Biophysics
Tyler M. Saumur, Sunita Mathur, Jacqueline Nestico, Stephen D. Perry, George Mochizuki, Avril Mansfield
Summary: The study aimed to determine the test-retest reliability of various force plate-derived measures of reactive stepping, finding that foot-off and swing times had higher reliability compared to step onset and restabilization times. The between-session reliability was higher than within-session reliability for all measures, with time to restabilization showing the worst absolute reliability. Multiple baseline sessions are recommended for measuring restabilization and step onset times, and the minimal detectable changes reported provide an index for measuring meaningful change due to intervention.
JOURNAL OF BIOMECHANICS
(2021)
Article
Engineering, Industrial
Yan-Xia Li, Lin Li, Xing Chen, Yang Zhao, Xi Zhao, Chong-Long Zhang
Summary: This study explored the test-retest reliability of grip force sense in healthy adult males and found that the reliability was highest at force levels of 20N and 50N. It is recommended that practitioners measure the absolute error and constant error when assessing grip force sense in a clinical setting.
Article
Radiology, Nuclear Medicine & Medical Imaging
Suzanne E. van Dijk, Jessie Lak, Nadieh Drenth, Anne Hafkemeijer, Serge A. R. B. Rombouts, Jeroen van der Grond, Sanneke van Rooden
Summary: Aging is associated with decreased cerebrovascular reactivity, measured by changes in BOLD response to visual stimulation. The BOLD amplitude appears to be a reliable measurement in healthy adults and presymptomatic D-CAA mutation carriers, but not in symptomatic D-CAA mutation carriers.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Behavioral Sciences
Giorgio Pigato, Stella Rosson, Nicola Bresolin, Tommaso Toffanin, Fabio Sambataro, Daniele Olivo, Giulia Perini, Francesco Causin, Luca Denaro, Andrea Landi, Domenico D'Avella
Summary: This study conducted a long-term follow-up on 5 patients with treatment-resistant depression (TRD) who received vagus nerve stimulation (VNS) implant. The results showed that VNS had long-lasting effectiveness in improving symptoms and functioning in patients with severe and chronic depression. The study supports VNS as a viable treatment option for TRD due to its sustained efficacy and good tolerability.
Article
Biochemistry & Molecular Biology
Nicolo Trevisan, Fabio Di Camillo, Niccolo Ghiotto, Giulia Cattarinussi, Maddalena Sala, Fabio Sambataro
Summary: In this study, the complexity of cortical folding (CCF) was compared between patients with cocaine addiction and controls. Patients with cocaine addiction showed reduced CCF in the left insula, the supramarginal gyrus, and the left medial orbitofrontal cortex. The reduction in cortical folding in the left medial orbitofrontal cortex was associated with the age of onset of cocaine addiction and attentional impulsivity.
Article
Substance Abuse
Gudrun M. Henemann, Mike M. Schmitgen, Nadine D. Wolf, Dusan Hirjak, Katharina M. Kubera, Fabio Sambataro, Tagrid Lemenager, Julian Koenig, Robert Christian Wolf
Summary: This study found a correlation between excessive smartphone use and the endogenous mu-opioid receptor (MOR) system using cross-modal correlations. The MOR system is closely linked to reward and withdrawal, suggesting its potential as a biological marker for technology-related addictive behaviors.
EUROPEAN ADDICTION RESEARCH
(2023)
Article
Multidisciplinary Sciences
Ramachandran Prakasam, Angela Bonadiman, Roberta Andreotti, Emanuela Zuccaro, Davide Dalfovo, Caterina Marchioretti, Debasmita Tripathy, Gianluca Petris, Eric N. Anderson, Alice Migazzi, Laura Tosatto, Anna Cereseto, Elena Battaglioli, Gianni Soraru, Wooi Fang Lim, Carlo Rinaldi, Fabio Sambataro, Naemeh Pourshafie, Christopher Grunseich, Alessandro Romanel, Udai Bhan Pandey, Andrea Contestabile, Giuseppe Ronzitti, Manuela Basso, Maria Pennuto
Summary: Prakasam and colleagues demonstrate that targeting overexpressed co-activators Lsd1 and Prmt6 with artificial miRNAs can attenuate polyQ-expanded androgen receptor toxicity, ameliorating spinal-bulbar muscular atrophy phenotypes in flies and mice. This study suggests that targeting these co-regulators could be a potential therapeutic strategy for patients with SBMA, as it helps mitigate toxic gain-of-function without exacerbating loss-of-function mechanisms.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Diana Piol, Laura Tosatto, Emanuela Zuccaro, Eric N. Anderson, Antonella Falconieri, Maria J. Polanco, Caterina Marchioretti, Federica Lia, Joseph White, Elisa Bregolin, Giovanni Minervini, Sara Parodi, Xavier Salvatella, Giorgio Arrigoni, Andrea Ballabio, Albert R. La Spada, Silvio C. E. Tosatto, Fabio Sambataro, Diego L. Medina, Udai B. Pandey, Manuela Basso, Maria Plennuto
Summary: Spinal and bulbar muscular atrophy is caused by polyglutamine expansions in androgen receptor, leading to gain-of-function toxicity. This study investigates the phosphorylation of polyglutamine-expanded receptor and its role in neurodegeneration. The researchers find that certain kinases and phosphatases can modify the function and toxicity of the receptor, and targeting these enzymes can potentially be used as a therapeutic approach.
Article
Neurosciences
Mario Luciano, Gaia Sampogna, Bianca Della Rocca, Alessio Simonetti, Pasquale De Fazio, Marco Di Nicola, Giorgio Di Lorenzo, Maria Pepe, Fabio Sambataro, Maria Salvina Signorelli, Alexia Emilia Koukopoulos, Roberto Delle Chiaie, Gabriele Sani, Andrea Fiorillo
Summary: This study investigated the relationship between affective temperaments and suicidality. It found that certain affective dispositions were associated with the onset and intensity of suicidal ideation and behaviors. Therefore, evaluating affective dispositions in clinical settings can help identify individuals at risk of suicide and develop effective preventive interventions.
Article
Psychiatry
Marouska M. van Ommen, Teus van Laar, Remco Renken, Frans W. Cornelissen, Richard Bruggeman
Summary: Approximately one-third of patients with psychotic disorder experience visual hallucinations, which may result from impaired functioning and interaction between vision-related networks. In this study, fMRI scans of 7 patients showed that V1 was not activated during hallucinations, but higher-order visual areas and networks related to attention and memory were active. These results suggest that hallucinations in psychotic disorder involve widespread involvement of vision-related networks.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Psychiatry
Branislava Curcic-Blake, Annemarie de Vries, Remco J. Renken, Jan Bernard C. Marsman, Jane Garrison, Kenneth Hugdahl, Andre Aleman
Summary: This study investigated the differences in brain structures between schizophrenia patients with auditory verbal hallucinations (AVH) and healthy controls. The findings revealed that patients with AVH had a longer length of PCS (paracingulate sulcus), while the clinical group fell between the healthy and AVH groups. Additionally, the cortical thickness surrounding the PCS region was significantly diminished in AVH patients compared to the healthy controls. These results contribute to further understanding the underlying mechanisms of hallucinations.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Neurosciences
A. C. L. Vrijling, M. J. de Boer, R. J. Renken, J. B. C. Marsman, A. Grillini, C. E. Petrillo, J. Heutink, N. M. Jansonius, F. W. Cornelissen
Summary: Human observers naturally track moving stimuli, and this tendency can be used for screening visual function. However, stimulus contrast is critical for detecting subtle impairments, as high contrast may mask performance decrease. To understand the effects of age, contrast, and stimulus movement on tracking performance, we evaluated younger and older participants' tracking of a moving stimulus at different contrast levels. Our findings provide insights into new approaches for screening visual function.
Article
Neurosciences
Nicolo Trevisan, Giulia Cattarinussi, Daniele Olivo, Andrea Di Ciano, Lucia Giudetti, Alan Pampallona, Katharina M. M. Kubera, Dusan Hirjak, Robert Christian Wolf, Fabio Sambataro
Summary: This study investigated the neural bases of social victimization using functional magnetic resonance imaging. The results showed increased activation in certain brain areas during social victimization, as well as correlations with personality traits such as neuroticism and irritability.
Article
Clinical Neurology
Alessandro Miola, Nicolo Trevisan, Margherita Salvucci, Matteo Minerva, Silvia Valeggia, Renzo Manara, Fabio Sambataro
Summary: Facial emotion recognition, especially for sadness, is impaired in bipolar disorder. The association between this impairment and brain structure, clinical variables, and subtypes of bipolar disorder remains unclear.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Review
Clinical Neurology
Mahan Shafie, Elnaz Shahmohamadi, Giulia Cattarinussi, Hossein Sanjari Moghaddam, Shahin Akhondzadeh, Fabio Sambataro, Chiara Moltrasio, Giuseppe Delvecchio
Summary: This review summarizes the findings of resting-state functional magnetic resonance imaging (rsfMRI) studies in individuals with borderline personality disorder (BPD). The results indicate aberrant functional connectivity within and between several brain networks, including the default mode network (DMN), salience network (SN), and central executive network (CEN), as well as selective functional impairments in specific brain regions. However, the generalizability of these results is limited by the observational design, small sample size, and heterogeneity across imaging methodologies.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Alessio Simonetti, Mario Luciano, Gaia Sampogna, Bianca Della Rocca, Emiliana Mancuso, Pasquale De Fazio, Marco Di Nicola, Giorgio Di Lorenzo, Maria Pepe, Fabio Sambataro, Maria Salvina Signorelli, Alexia Emilia Koukopoulos, Roberto Delle Chiaie, Andrea Fiorillo, Gabriele Sani
Summary: This multicentric observational study aimed to investigate the relationship between affective temperaments and bipolar disorder (BD) or major depressive disorder (MDD), as well as their influence on the severity and course of the diseases. The results revealed that specific affective temperaments were associated with certain disease characteristics. Evaluating affective temperaments may contribute to a better understanding of mood disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Meeting Abstract
Psychiatry
N. Trevisan, F. Di Camillo, G. Cattarinussi, N. Ghiotto, M. Sala, F. Sambataro
EUROPEAN PSYCHIATRY
(2023)
Review
Biochemistry & Molecular Biology
Michele Fornaro, Claudio Caiazza, Niccolo Solini, Michele De Prisco, Martina Billeci, Martina Vannini, Risa Shorr, Stefano Caiolo, Marialaura Lussignoli, Dan Siskind, Giorgio Pigato, Annarita Barone, Fabio Sambataro, Andrea de Bartolomeis, Christoph U. Correll, Marco Solmi
Summary: This study conducted a network meta-analysis on antipsychotic-induced sialorrhea. The results showed that dopamine receptor antagonists, metoclopramide, and sulpiride were effective in treating sialorrhea, while antihistamines and atropine showed no significant effect on nocturnal sialorrhea. This study provides some guidance for the treatment of antipsychotic-related sialorrhea.
MOLECULAR PSYCHIATRY
(2023)
