Article
Public, Environmental & Occupational Health
Chonin Cheang, Saikam Law, Jieru Ren, Wengtong Chan, Cunchuan Wang, Zhiyong Dong
Summary: This study found an association between serum uric acid levels and obesity in Chinese patients. Patients with overweight and different degrees of obesity had higher prevalence of hyperuricemia, and serum uric acid was significantly correlated with BMI, waist circumference, and hip circumference.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Juan Sun, Chenyang Yue, Zhen Liu, Jie Li, Weiming Kang
Summary: This study revealed a significant positive relationship between total percent fat (TPF) and serum uric acid (SUA) among adults. This association remained statistically significant when stratified by sex and obesity status, but the shape of the smoothing curve differed between males and females.
FRONTIERS IN NUTRITION
(2022)
Article
Endocrinology & Metabolism
Yi Zhang, Min Tan, Boyu Liu, Manxia Zeng, You Zhou, Mengru Zhang, Yikai Wang, Jing Wu, Min Wang
Summary: This study aims to examine the association between bone mineral density (BMD) and hyperuricemia (HU) in obesity. The results showed a negative correlation between lumbar BMD and HU in obese individuals, particularly in men, while no significant relationship was found between hip BMD and HU.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Vlad-Sabin Ivan, Roxana Buzas, Adina-Flavia Cutina Morgovan, Paul Ciubotaru, Melania Ardelean, Daniel Goje, Ilie Rosca Ciprian, Romulus Timar, Daniel Lighezan
Summary: The study examined the direct relationship between serum uric acid and ejection fraction in 303 heart failure patients, concluding that higher uric acid levels are associated with a lower ejection fraction of the left ventricle.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Fengyu Han, Chao Yu, Feng Hu, Wei Zhou, Tao Wang, Linjuan Zhu, Xiao Huang, Huihui Bao, Xiaoshu Cheng
Summary: According to this cross-sectional study, higher SUA levels were positively associated with PAD in male hypertensive patients, while this positive relationship disappeared in female participants.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Noyan Hossain Molla, Rahanuma Raihanu Kathak, Abu Hasan Sumon, Zitu Barman, Ananya Dutta Mou, Akibul Hasan, Firoz Mahmud, Khandaker Atkia Fariha, Nurshad Ali
Summary: The study found a positive correlation between serum uric acid and liver enzymes (ALT and GGT) in adults in Bangladesh. Men had higher mean uric acid levels than women, and men also had significantly higher levels of liver enzymes than women.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Yongzheng Hang, Lina Zou, Lan Jiang, Xueqing Zhang, Xiaojing Huang, Yanan Liu, Zhiren Zhou, Hongzhi Pan, Hongkun Ma, Shengzhong Rong
Summary: The study found a positive correlation between VFA and hyperuricemia, indicating that VFA may serve as a crucial predictive marker for hyperuricemia.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Medicine, General & Internal
Meng-Ko Tsai, Kuang-Chen Hung, Chun-Cheng Liao, Lung-Fa Pan, Chia-Lien Hung, Deng-Ho Yang
Summary: This study found that low testosterone levels in men may be associated with an increased risk of hyperuricemia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Endocrinology & Metabolism
Rong Xu, Difei Lian, Yan Xie, Lin Mu, Yali Wu, Zhilei Chen, Baoyu Zhang
Summary: Osteoporosis is a systemic bone disease characterized by decreased bone density and quality, leading to bone fragility and increased risk of fractures. The development of osteoporosis is closely associated with oxidative stress, and uric acid plays a role in bone metabolism by acting as an antioxidant. However, the degradation of uric acid can lead to intracellular oxidative stress and inflammatory factors, contributing to bone destruction. Additionally, uric acid can inhibit vitamin D production, exacerbating bone loss. This review summarizes the relationship between serum uric acid levels and bone mineral density, bone turnover markers, etc., aiming to provide new insights into the pathogenesis and treatment of osteoporosis.
ENDOCRINE CONNECTIONS
(2023)
Article
Geriatrics & Gerontology
Fuyin Kou, Shanshan Yang, Shengshu Wang, Miao Liu, Yao He
Summary: The average SUA level among centenarians was 329.0±97.75μmol/L, with a prevalence of hyperuricemia at 26.5%. While no significant association was found between SUA levels and hypertension/diabetes, there was an independent positive association with dyslipidemia, particularly with hypertriglyceridemia and low-density lipoprotein cholesterolemia.
Article
Environmental Sciences
Wei Piao, Ya Cong Bo, Li Yun Zhao, Dong Mei Yu
Summary: The study found that the average serum uric acid levels among Chinese adults are relatively high, with a significant prevalence of hyperuricemia. Levels are generally higher in urban areas compared to rural areas, and the eastern region showed a higher prevalence compared to other regions.
BIOMEDICAL AND ENVIRONMENTAL SCIENCES
(2022)
Article
Medicine, General & Internal
Jie Zeng, Wayne R. Lawrence, Jun Yang, Junzhang Tian, Cheng Li, Wanmin Lian, Jingjun He, Hongying Qu, Xiaojie Wang, Hongmei Liu, Guanming Li, Guowei Li
Summary: The study found that higher SUA levels were associated with an increased risk of obesity, with a greater risk in women and young participants. Further research is needed to confirm these findings.
Article
Rheumatology
Jie Wei, Yuqing Zhang, Nicola Dalbeth, Robert Terkeltaub, Tuo Yang, Yilun Wang, Zidan Yang, Jiatian Li, Ziying Wu, Chao Zeng, Guanghua Lei
Summary: This study found an association between dysbiosis of gut microbiota and hyperuricemia, suggesting a potential role of microbiota dysbiosis in modulating serum urate levels.
ARTHRITIS & RHEUMATOLOGY
(2022)
Article
Nutrition & Dietetics
Xiaojing Feng, Yanyi Yang, Huiqi Xie, Siqi Zhuang, Yiyuan Fang, Yufeng Dai, Ping Jiang, Hongzhi Chen, Haoneng Tang, Lingli Tang
Summary: This study found a positive association between hyperuricemia and overweight/obese metabolic phenotypes, regardless of sex and age.
FRONTIERS IN NUTRITION
(2022)
Article
Endocrinology & Metabolism
Xuebiao Wei, Bingqi Fu, Xiaolan Chen, WeiTao Chen, Zhenqian Wang, Danqing Yu, Guozhi Jiang, Jiyan Chen
Summary: There is a U-shaped relationship between uric acid levels and in-hospital death in patients with infective endocarditis, with low and high levels of uric acid predictive of increased short-term mortality.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Rahanuma Raihanu Kathak, Abu Hasan Sumon, Noyan Hossain Molla, Mahmudul Hasan, Rakib Miah, Humaira Rashid Tuba, Ahsan Habib, Nurshad Ali
Summary: The study found a high prevalence of dyslipidemia and liver enzyme abnormalities among Bangladeshi adults. Serum GGT levels showed an independent association with all lipid components. Moreover, patients with dyslipidemia have a higher risk of liver diseases.
SCIENTIFIC REPORTS
(2022)
Article
Toxicology
Nicholas N. A. Kyei, Benedikt Cramer, Hans-Ulrich Humpf, Gisela H. Degen, Nurshad Ali, Sabine Gabrysch
Summary: This study investigates the exposure of 439 pregnant women in rural Bangladesh to 35 mycotoxins and their corresponding health risks and finds that exposure to multiple mycotoxins during early pregnancy is widespread in this rural community and represents a potential health risk for mothers and their offspring.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Engineering, Environmental
Nayan C. Mohanto, Yuki Ito, Sayaka Kato, Takeshi Ebara, Kayo Kaneko, Tomoyuki Tsuchiyama, Mayumi Sugiura-Ogasawara, Shinji Saitoh, Michihiro Kamijima
Summary: This study assessed the exposure risks of 1.5-year-old toddlers to phthalates and found that some toddlers were exposed to levels higher than the cutoff value, indicating potential health risks. Therefore, measures should be taken to identify sources of exposure and mitigate the risks.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Rakib Miah, Khandaker Atkia Fariha, Sabrina Amita Sony, Shamim Ahmed, Mahmudul Hasan, Ananya Dutta Mou, Zitu Barman, Akibul Hasan, Nayan Chandra Mohanto, Nurshad Ali
Summary: This study found a significant correlation between serum xanthine oxidase (XO) levels and hypertension, with XO positively correlated with systolic blood pressure (SBP) and diastolic blood pressure (DBP). This suggests that XO may play a role in the pathophysiology of hypertension through the generation of reactive oxygen species.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Mahmudul Hasan, Khandaker Atkia Fariha, Zitu Barman, Ananya Dutta Mou, Rakib Miah, Ahsan Habib, Humaira Rashid Tuba, Nurshad Ali
Summary: This study found a positive and independent association between XO levels and T2D in Bangladeshi adults. Monitoring serum XO levels may be useful in reducing the risk of T2D.
SCIENTIFIC REPORTS
(2022)
Review
Biotechnology & Applied Microbiology
Sutapa Bhowmik, Nayan Chandra Mohanto, Dipanjon Sarker, Asma Ahsan Sorove
Summary: The incidence and risk of lung cancer are higher in tuberculosis patients, while the incidence and risk of tuberculosis are relatively low in lung cancer patients. Male patients have a higher risk compared to females. Medical comorbidities, smoking habits, and age also influence the associations and risks of both diseases.
BIOMED RESEARCH INTERNATIONAL
(2022)
Article
Toxicology
Nicholas N. A. Kyei, Jillian L. Waid, Nurshad Ali, Benedikt Cramer, Hans-Ulrich Humpf, Sabine Gabrysch
Summary: Limited and inconsistent evidence suggests a potential link between mycotoxins and adverse birth outcomes. This study examines the role of maternal dietary exposure to multiple mycotoxins in the development of adverse pregnancy and birth outcomes. The findings indicate that exposure to OTA is associated with higher odds of low birth weight babies.
ARCHIVES OF TOXICOLOGY
(2023)
Article
Endocrinology & Metabolism
Zitu Barman, Mahmudul Hasan, Rakib Miah, Ananya Dutta Mou, Jaasia Momtahena Hafsa, Aporajita Das Trisha, Firoz Mahmud, Nurshad Ali
Summary: This study aimed to estimate the prevalence of chronic kidney disease (CKD) and assess its relationship with hyperuricemia in Bangladeshi adults. The results showed that the prevalence of CKD was 5.9%, with 6.1% in males and 5.2% in females. Hyperuricemia was prevalent in 18.7% of participants, with higher rates in males (23.2%) than in females (14.6%). There was a significant positive association between hyperuricemia and CKD.
BMC ENDOCRINE DISORDERS
(2023)
Article
Multidisciplinary Sciences
Nurshad Ali, Shamim Ahmed, Shakil Mahmood, Aporajita Das Trisha, Firoz Mahmud
Summary: Obesity is a major risk factor for hypertension and other diseases, while hypertension is a leading cause of cardiovascular disease. This study aimed to determine the prevalence and factors associated with obesity and hypertension among university academic staff in Bangladesh. The results showed that female staff had a higher prevalence of obesity, while male staff had a higher prevalence of hypertension. Comprehensive screening programs are needed to address the high prevalence of obesity and hypertension in this group.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Nurshad Ali, Rahanuma Raihanu Kathak, Khandaker Atkia Fariha, Abu Taher, Farjana Islam
Summary: This study investigated the prevalence and factors related to dyslipidemia among university academic staff and students in Bangladesh. The results showed that dyslipidemia was prevalent among the majority of the study participants and was significantly associated with increased age, obesity, diabetes, and inadequate physical activity. The study's findings highlight the importance of implementing interventions to address the associated risk factors of dyslipidemia among academic staff and students in Bangladesh.
BMC CARDIOVASCULAR DISORDERS
(2023)
Review
Engineering, Environmental
Nurshad Ali, Joseph Xavier, Melih Engur, P. Mohanan, Jorge Bernardino de la Serna
Summary: The use of e-cigarettes is increasing worldwide, but little is known about their adverse effects on human health. This review summarizes the impact of e-cigarette exposure on different organ systems, suggesting that while they cause less harm than traditional cigarettes, long-term exposure may still lead to serious health effects. Short-term organ effects and the potential dangers of secondhand and third hand exposure have not been thoroughly investigated. More research is needed to draw a firm conclusion about the safe use of e-cigarettes.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Endocrinology & Metabolism
Nurshad Ali, Mitu Samadder, Firoz Mahmud, Farjana Islam
Summary: This study demonstrates that elevated levels of ALT and GGT are independently associated with MetS and its components.
EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM
(2023)
Article
Multidisciplinary Sciences
Nurshad Ali, Mitu Samadder, Rahanuma Raihanu Kathak, Farjana Islam
Summary: This study aimed to estimate the prevalence and factors associated with dyslipidemia in Bangladeshi adults. The results showed a high prevalence of dyslipidemia among Bangladeshi adults, and it was closely associated with age, overweight, obesity, diabetes, hypertension, and low physical activity.
Article
Multidisciplinary Sciences
Nurshad Ali, Mitu Samadder, Jahid Hasan Shourove, Abu Taher, Farjana Islam
Summary: This study aimed to determine the prevalence of Metabolic syndrome (MetS) and associated risk factors among university students and academic staff in Bangladesh. The results showed a high prevalence of MetS in both groups, with age, BMI, hypertension, and dyslipidemia being independently associated with the risk of MetS.
SCIENTIFIC REPORTS
(2023)