Article
Environmental Sciences
Kangyu Hao, Jia Luo, Jing Sun, Honghan Ge, Zhaoguo Wang
Summary: The study found that exposure to BPA and BPS was positively associated with depressive symptoms, especially in men. However, BPS was negatively associated with depressive symptoms in elderly women.
Article
Environmental Sciences
Chen Yujiao, Zhang Meng, Li Shanshan, Wang Wei, Wang Yipeng, Yin Chenghong
Summary: This study found that fetal heart development abnormalities can be induced by maternal exposure to bisphenol A (BPA), and suggested that this may be mediated by the cell ferroptosis mechanism regulated by system Xc.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Biochemistry & Molecular Biology
Erico A. Oliveira Pereira, Lisa M. Labine, Sonya Kleywegt, Karl J. Jobst, Andre J. Simpson, Myrna J. Simpson
Summary: This study found that BPA, BPF, and BPS elicited similar non-monotonic concentration responses on the metabolism of Daphnia magna, with pathways related to protein synthesis, amino acid metabolism, and energy metabolism being perturbed. The results suggest a need for metabolomic analyses in exposure assessment for chemicals within the same class that may disrupt biochemistry uniquely at the molecular level.
Article
Environmental Sciences
Yali Liu, Yongli Wu, Geng Qin, Yu Chen, Xin Wang, Qiang Lin
Summary: This study revealed that exposure to BPA at environmentally relevant concentrations may cause reproductive dysfunction in seahorses. Ovarian failure was observed in the high-dose BPA treatment group, while maintenance of brood pouches was inhibited at low concentrations, suggesting differential impacts of BPA on seahorses.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Cell Biology
Santokh Gill, V. M. Ruvin Kumara
Summary: The study compared the neurodevelopmental effects of BPA and its major replacement BPF on rat fetal neural stem cells, revealing that both compounds increase cell proliferation and impact differentiation rates of oligodendrocytes and neurons. There were concentration-dependent decreases in the maturation of oligodendrocytes and neurons, with a concomitant increase in immature cells.
Article
Environmental Sciences
Jillian Ashley-Martin, Eric Gaudreau, Pierre Dumas, Chun Lei Liang, Agata Logvin, Patrick Belanger, Gilles Provencher, Sebastien Gagne, Warren Foster, Bruce Lanphear, Tye E. Arbuckle
Summary: This study compared urinary BPA concentrations estimated from indirect and direct methods in pregnant women's urine samples. The direct method showed on average 8.6% higher BPA concentrations than the indirect method, with smaller differences in urine with lower specific gravity and larger differences in samples below the limit of quantification (LOQ).
ENVIRONMENT INTERNATIONAL
(2021)
Review
Environmental Sciences
Sandra M. Colorado-Yohar, Ana C. Castillo-Gonzalez, Julio Sanchez-Meca, Maria Rubio-Aparicio, Diego Sanchez-Rodriguez, Elena Salamanca-Fernandez, Eva Ardanaz, Pilar Amiano, Mariana F. Fernandez, Jaime Mendiola, Fernando Navarro-Mateu, Maria Dolores Chirlaque
Summary: This meta-analysis highlights the widespread exposure of the general human population to BPA. Despite high heterogeneity across studies, the estimated range of BPA concentrations suggests that potential health risks are unlikely.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Gerardo Heredia-Garcia, Gustavo Axel Elizalde-Velazquez, Leobardo Manuel Gomez-Olivan, Hariz Islas-Flores, Sandra Garcia-Medina, Marcela Galar-Martinez, Octavio Dublan-Garcia
Summary: This study aimed to assess the neurotoxic effects of acute BPA exposure at environmentally relevant concentrations in adult zebrafish. Results showed that exposure to 1500 ng/L of BPA reduced swimming distance and increased freezing time. Biomarker evaluation revealed the production of reactive oxygen species and increased acetylcholinesterase activity in the zebrafish brain. Gene expression analysis also indicated overexpression of mbp, alpha 1-tubulin, and manf. Based on these findings, it can be concluded that environmentally relevant concentrations of BPA can cause anxiety-like behavior and neurotoxic effects in adult zebrafish.
Article
Biochemistry & Molecular Biology
Aeman Zahra, Rachel Kerslake, Ioannis Kyrou, Harpal S. Randeva, Cristina Sisu, Emmanouil Karteris
Summary: This paper presents a detailed analysis of the changes in gene expression in normal human ovarian cells treated with the xenoestrogen BPA. The study reveals that BPA exposure affects the expression of several genes, including those related to oocyte maturation. Further research is needed to explore the effects of BPA in ovarian health and disease using validated in vitro and in vivo models, in order to fill knowledge gaps in basic biology, hazard characterization, and risk assessment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Krystyna Makowska, Marta Staniszewska, Karina Bodziach, Jaroslaw Calka, Slawomir Gonkowski
Summary: This study evaluated the levels of BPA in pork meat and found that it may be a source of BPA in human food. Animals receiving higher doses of BPA had increased concentrations of BPA in their meat.
Article
Environmental Sciences
Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande, Susana Santos
Summary: Higher maternal bisphenol S urine concentrations, especially in the first trimester, seem to be associated with larger fetal head circumference, higher weight, and a lower risk of being small size for gestational age at birth. Other bisphenols were not consistently associated with fetal growth outcomes.
ENVIRONMENTAL HEALTH
(2021)
Article
Endocrinology & Metabolism
Annalisa Deodati, Giorgia Bottaro, Daniela Germani, Fabrizia Carli, Sabrina Tait, Luca Busani, Veronica Della Latta, Anna Paola Pala, Francesca Maranghi, Roberta Tassinari, Amalia Gastaldelli, Cinzia La Rocca, Stefano Cianfarani
Summary: This study aimed to determine the urinary excretion of bisphenol A and phthalates in obese and normal weight children. Through a case-control study, it was found that obese girls had significantly higher levels of urinary bisphenol A compared to normal weight girls, and the metabolites of phthalates correlated significantly with leptin concentrations in obese girls. The results suggest that higher exposure to bisphenol A is associated with an increased risk of obesity in girls.
HORMONE RESEARCH IN PAEDIATRICS
(2023)
Article
Environmental Sciences
Hao Wang, Shaoyu Tang, Xi Zhou, Rui Gao, Zehua Liu, Xiaofei Song, Feng Zeng
Summary: This study assessed human exposure to Bisphenol analogues (BPs) through investigating pooled urine and wastewater samples. BPA, BPS, and BPAF were widely detected in both urine and wastewater samples, indicating industrial wastewater and household cleaning products as important sources of BPs. Urinary BPA, BPS, and BPAF accounted for less than 5% per capita mass loads in wastewater, suggesting non-human sources in municipal wastewater.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Susanna D. Mitro, Rajeshwari Sundaram, Germaine M. Buck Louis, Shyamal Peddada, Zhen Chen, Kurunthachalam Kannan, Jessica L. Gleason, Cuilin Zhang, Katherine L. Grantz
Summary: This study found that certain PFAS were associated with growth in small fibroids and reduction in medium-sized fibroids. PFAS may influence existing fibroids rather than initiating fibroid development.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Article
Medicine, Legal
Bradford D. Bagley, Jordan N. Smith, Justin G. Teeguarden
Summary: The study reveals that exposure to BPA from dental and orthodontic devices is very low and does not pose a risk to patients.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Chunxia Meng, Jin Hou
MATERIALS SCIENCE-MEDZIAGOTYRA
(2019)
Article
Multidisciplinary Sciences
Carlos Diaz-Castillo, Raquel Chamorro-Garcia, Toshi Shioda, Bruce Blumberg
SCIENTIFIC REPORTS
(2019)
Article
Environmental Sciences
Chunxia Meng, Xilai Zheng, Jin Hou, Chengjian Wang
WATER AIR AND SOIL POLLUTION
(2020)
Article
Oceanography
Liu Xiaojie, Hao Ting, Feng Lijuan, Ji Yinli, Wang Qianqian, Zhang Dahai, Pan Gang, Gao Xianchi, Meng Chunxia, Li Xianguo
Summary: The study analyzed organic biomarker parameters in surface sediment samples from the East China Sea inner shelf to trace the transport of terrigenous organic matters. Long-chain alkanes were found to be mainly terrestrial in origin, and the area showed signs of petroleum pollution. Additionally, a strong reductive sedimentary condition was observed in the region.
JOURNAL OF OCEAN UNIVERSITY OF CHINA
(2021)
Article
Engineering, Chemical
Kaiyue Ding, Guiru Zhu, Chenghao Song, Qi Wang, Lin Wang, Ziqi Wang, Chunxia Meng, Congjie Gao
Summary: The ESNM-H prepared by electrospinning method shows high adsorption capacity and selectivity for Li+, good long-term stability, and potential applications for adsorption of Li(+) from salt-lake brine with recyclability.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Julia A. Taylor, Benjamin L. Coe, Toshi Shioda, Frederick S. vom Saal
Summary: Differential placental blood flow and nutrient transport can lead to both intrauterine growth restriction (IUGR) and macrosomia, which in turn can result in adult obesity and metabolic syndrome. The study used a crowded uterus model to compare IUGR and macrosomia in male mice. It identified rapid and low postweaning weight gain in IUGR males, with rapid growth leading to glucose intolerance and down-regulation of adipocyte signaling pathways. Macrosomia resulted in increased fat mass and altered adipocyte size distribution, as well as down-regulation of signaling pathways for carbohydrate and fat digestion and absorption. Clustering analysis indicated more similarities between IUGR males with rapid postweaning growth and macrosomic males than IUGR males with low postweaning weight gain.
Article
Biochemistry & Molecular Biology
Keiko Shioda, Junko Odajima, Bruce Blumberg, Toshi Shioda
Summary: Obesogens such as TBT can promote obesity by distorting lipid metabolism. The offspring of TBT-exposed mice showed increased body fat accumulation, loss of body fluid and lean compositions. TBT exposure also affected gene expression and epigenetic suppression in the testes.
Article
Biochemistry & Molecular Biology
Baojun Sun, Yajie Sun, Shuwei Han, Ruitong Zhang, Xiujuan Wang, Chunxia Meng, Tuo Ji, Chunhui Sun, Na Ren, Shaohua Ge, Hong Liu, Yang Yu, Jingang Wang
Summary: Traditional bone defect treatments face limitations due to insufficient supply of autologous bone, immune rejection of allogeneic bone grafts, and high medical costs. To overcome these limitations, bone tissue engineering with electroactive scaffolds has emerged as a promising option. However, current electroactive scaffolds are either single-function and not suitable for scientific research and clinical application, or complex and expensive to prepare. This study proposes a new tissue engineering strategy to optimize the electrical properties and biocompatibility of carbon-based materials.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Limnology
Xihuang Zhong, Xueyan Jiang, Huijun He, Wenwen Zhang, Chunxia Meng, Feng Sun
Summary: The geochemical behaviors of heavy metals, particularly uranium, in river sediments were analyzed using sequential extraction method. The results showed that uranium exists mainly in the residual form, followed by organic matter or sulfide, Fe-Mn oxides, carbonates, and exchangeable forms. The main source of uranium in the sediments was weathered rock in the drainage basin, and there was also a potential exogenous input in certain areas. Fe-Mn oxides and secondary minerals like calcite and illite play important roles in the speciation of uranium.
JOURNAL OF OCEANOLOGY AND LIMNOLOGY
(2023)
Article
Endocrinology & Metabolism
Richard C. Chang, Erika M. Joloya, Zhuorui Li, Bassem M. Shoucri, Toshi Shioda, Bruce Blumberg
Summary: Exposure to the obesogen tributyltin (TBT) during pregnancy predisposes male offspring to obesity and diverts mesenchymal stem cells (MSCs) towards adipogenesis. TBT promotes adipogenic commitment and differentiation of MSCs in vitro. Through transcriptomic analysis, miR-223 was identified as a key microRNA regulating adipogenesis in response to TBT exposure.
Article
Endocrinology & Metabolism
Keiko Shioda, Junko Odajima, Misato Kobayashi, Mutsumi Kobayashi, Bianca Cordazzo, Kurt J. Isselbacher, Toshi Shioda
Summary: Transcriptomic, DNA methylome, and immunofluorescence analyses of feminized FemZZs showed that these gonads maintain significant transcriptomic and epigenetic memories of male sex, including key masculinizing genes such as DMRT1. The study identified specific genes and repetitive sequences that were strongly expressed in FemZZs but suppressed in normal female ovaries, highlighting the resistance of certain genetic markers to feminization.
Proceedings Paper
Engineering, Electrical & Electronic
Liang Zhang, Chun Xia Meng, Ming Wei Zhang
PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON MECHATRONICS AND INTELLIGENT ROBOTICS (ICMIR-2019)
(2020)
Proceedings Paper
Computer Science, Information Systems
Liang Zhang, Xiao Yuan Li, Chun Xia Meng
2020 IEEE INTERNATIONAL CONFERENCE ON SIGNAL PROCESSING, COMMUNICATIONS AND COMPUTING (IEEE ICSPCC 2020)
(2020)
Meeting Abstract
Pharmacology & Pharmacy
Rui Wang, Chunxia Meng
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2020)
Proceedings Paper
Mathematics, Applied
Liang Zhang, Chunxia Meng
PROCEEDINGS OF THE 2018 3RD INTERNATIONAL CONFERENCE ON MODELLING, SIMULATION AND APPLIED MATHEMATICS (MSAM 2018)
(2018)