期刊
PLACENTA
卷 79, 期 -, 页码 40-45出版社
W B SAUNDERS CO LTD
DOI: 10.1016/j.placenta.2018.11.003
关键词
Fetal membranes; Structure; Senescence; Inflammation
资金
- National Health and Medical Research Council (NHMRC) [454777, 1047025]
- University of Melbourne
- NHMRC [367615, 1058786]
- Melbourne Research Grant Scheme (MRGS)
- ANZ Charitable Trust (Medical Research and Technology Grant)
- Norman Beischer Medical Research Foundation
- Mercy Research Foundation
Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.
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