期刊
ORGANIC LETTERS
卷 20, 期 21, 页码 6863-6867出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b02988
关键词
-
资金
- Heriot-Watt University
- Leverhulme Trust [RPG-2016-008]
Contrary to the accepted convention, this work shows that Minisci-type C-H alkylation does not require any metal, photocatalyst, light, or prefunctionalization of the readily available and inexpensive carboxylic acids to proceed well under mild conditions. These mild conditions can be utilized for late-stage alkylations of complex molecules, including pharmaceutical compounds and light-sensitive compounds which degrade under photocatalytic conditions.
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