PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response

Compromised BRCA1–PALB2 interaction is associated with breast cancer risk

(2017) T K Foo et al.   ONCOGENE

A mechanism for the suppression of homologous recombination in G1 cells

(2015) Alexandre Orthwein et al.   NATURE

Male Fertility Defect Associated with Disrupted BRCA1-PALB2 Interaction in Mice

(2014) Srilatha Simhadri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery

(2014) Anar K. Murphy et al.   JOURNAL OF CELL BIOLOGY

Two Decades After BRCA: Setting Paradigms in Personalized Cancer Care and Prevention

(2014) F. J. Couch et al.   SCIENCE

Cancer Suppression by the Chromosome Custodians, BRCA1 and BRCA2

(2014) A. R. Venkitaraman   SCIENCE

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

(2014) Andrés Cruz-García et al.   Cell Reports

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

(2013) Jacqueline H. Barlow et al.   CELL

Autophagy Opposes p53-Mediated Tumor Barrier to Facilitate Tumorigenesis in a Model of PALB2-Associated Hereditary Breast Cancer

(2013) Y. Huo et al.   Cancer Discovery

Hereditary Breast Cancer: The Era of New Susceptibility Genes

(2013) Paraskevi Apostolou et al.   Biomed Research International

PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function

(2012) J. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation

(2012) S Shabbeer et al.   ONCOGENE

A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

(2011) Tobias Menzel et al.   EMBO REPORTS

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

(2011) T. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

(2011) C. Cotta-Ramusino et al.   SCIENCE

PALB2/FANCN: Recombining Cancer and Fanconi Anemia

(2010) M. Tischkowitz et al.   CANCER RESEARCH

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A High-Throughput Pharmaceutical Screen Identifies Compounds with Specific Toxicity against BRCA2-Deficient Tumors

(2009) B. Evers et al.   CLINICAL CANCER RESEARCH

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

Structural basis for recruitment of BRCA2 by PALB2

(2009) Antony W Oliver et al.   EMBO REPORTS

PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2

(2009) F. Zhang et al.   MOLECULAR CANCER RESEARCH

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA