Article
Immunology
Katie Phair, Sonia Gonsalves Pereira, Carmel Kealey, Seamus Fanning, Damien B. Brady
Summary: Cronobacter species enhance their virulence through various mechanisms during survival in the environment, infection of hosts, and persistence inside hosts. Cronobacter sakazakii is associated with fatal infections in populations such as neonates and infants.
MICROBIAL PATHOGENESIS
(2022)
Review
Biotechnology & Applied Microbiology
Ziqiu Lin, Shimei Pang, Zhe Zhou, Xiaozhen Wu, Pankaj Bhatt, Shaohua Chen
Summary: This paper discusses the toxic effects of the herbicide butachlor on aquatic and terrestrial animals, including humans, as well as the resistance developed in some organisms. It also explores the potential of using butachlor-resistant organisms for removing residues from the environment, focusing on microbial degradation methods. The study further investigates the biochemical pathways and molecular mechanisms of butachlor biodegradation for repairing contaminated environments.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Review
Environmental Sciences
Muhammad Shehzad, Imran Bodlah, Junaid Ali Siddiqui, Muhammad Adnan Bodlah, Ammara Gull E. Fareen, Waqar Islam
Summary: Insects are highly successful and diverse, but they pose a significant threat to agriculture, with potential losses of up to US$470 billion. Plutella xylostella, a devastating pest that attacks cruciferous vegetables, alone causes monetary losses of around US$4-5 billion worldwide. Insecticides have protected plants effectively, but their use comes with environmental and mammalian hazards, and insects are developing resistance to them. Understanding the mechanisms behind this resistance is crucial for addressing the issue and improving the effectiveness of insecticides.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Environmental Sciences
Muhammad Shehzad, Imran Bodlah, Junaid Ali Siddiqui, Muhammad Adnan Bodlah, Ammara Gull E. Fareen, Waqar Islam
Summary: Insects pose a significant threat to agricultural crops, resulting in potential losses of up to US$470 billion. Among these pests, Plutella xylostella is a devastating insect that attacks cruciferous vegetables, causing approximately US$4-5 billion in monetary losses worldwide. Understanding the mechanisms of insecticide resistance is crucial for developing effective management strategies.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Medicine, General & Internal
Hanna Szmygin, Maciej Szmygin, Mateusz Cheda, Bartosz Klobuszewski, Anna Drelich-Zbroja, Beata Matyjaszek-Matuszek
Summary: Obesity has become a major global health concern, affecting approximately 650 million people worldwide and causing significant comorbidities. Recent studies have found that obesity leads to changes in both structure and connectivity within the central nervous system, and fMRI may be a useful tool in detecting these changes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Immunology
Shengman Yu, Xiaoyan Li, Zhuoyuan Xin, Liyuan Sun, Jingwei Shi
Summary: In this review, the proteomic studies of SARS-CoV-2 infection are summarized, providing insights into viral particles and host entry factors from a protein perspective, as well as analyzing protein pathological changes following host infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Cell Biology
Jiahong Sun, Prema Vyas, Samar Mann, Annlia Paganini-Hill, Ane C. F. Nunes, Wei Ling Lau, David H. Cribbs, Mark J. Fisher, Rachita K. Sumbria
Summary: This study elucidated the cellular mechanisms underlying brain endothelial erythrophagocytosis, highlighting the key roles of RBC phosphatidylserine exposure and ROS. The process may lead to iron-rich cerebral microhemorrhage-like lesions, demonstrating a new route for RBC entry into the brain.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Armanda Wojtasinska, Weronika Frak, Wiktoria Lisinska, Natalia Sapeda, Ewelina Mlynarska, Jacek Rysz, Beata Franczyk
Summary: Atherosclerosis is a deadly disease with complex pathophysiology involving thickening of arterial walls. Scientists from various disciplines are actively researching its molecular and cellular mechanisms. This review summarizes the current knowledge on the implications of atherosclerosis, focusing on factors such as endothelium dysfunction, inflammation, aging, uric acid, vitamin D, and miRNA expression. Understanding the underlying causes of this condition can contribute to improved prevention and treatment of cardiovascular diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Yongsheng Chen, Wen-Juan Chen, Yaohua Huang, Jiayi Li, Jianfeng Zhong, Wenping Zhang, Yi Zou, Sandhya Mishra, Pankaj Bhatt, Shaohua Chen
Summary: Glyphosate, a broad-spectrum herbicide, is widely distributed and poses a serious threat to human safety and ecology. Microbial degradation has emerged as a promising method for treating glyphosate due to its efficiency and environmental friendliness. Microorganisms can utilize glyphosate as a nutrient source and degrade it into harmless products by cleaving specific bonds. However, the enzymes and functional genes involved in glyphosate degradation and the resistance mechanisms of microorganisms to glyphosate are not well understood.
ENVIRONMENTAL RESEARCH
(2022)
Review
Environmental Sciences
Yaohua Huang, Wenping Zhang, Shimei Pang, Junmin Chen, Pankaj Bhatt, Sandhya Mishra, Shaohua Chen
Summary: Chlorpyrifos is widely used as an insecticide, but its long-term and irregular applications have caused environmental pollution and toxic effects on non-target organisms. Microbial metabolism-based bioremediation is an effective strategy to remove chlorpyrifos residues.
ENVIRONMENTAL RESEARCH
(2021)
Review
Plant Sciences
Muhammad Rahil Afzal, Misbah Naz, Justin Wan, Zhicong Dai, Raza Ullah, Shafiq Ur Rehman, Daolin Du
Summary: Invasive plant species have the remarkable ability to establish and displace native species in new environments. Their success is attributed to various physiological and biochemical mechanisms that enable them to tolerate adverse environmental conditions, such as high lead toxicity. Research on the mechanisms responsible for lead tolerance in invasive plants is rapidly evolving, with several strategies being identified. This review article provides a comprehensive understanding of the current research on lead tolerance mechanisms in invasive plants and discusses their potential applications in remediating lead-contaminated soils and developing resilient crops.
Review
Environmental Sciences
Sandhya Mishra, Shimei Pang, Wenping Zhang, Ziqiu Lin, Pankaj Bhatt, Shaohua Chen
Summary: Carbamate compounds, commonly used in agriculture as alternatives to persistent organochlorine pesticides, pose toxic environmental residues due to their inhibitor activity against acetylcholinesterase enzyme. Microbial technology can be an efficient and eco-friendly tool for carbamate insecticide degradation in contaminated environments, utilizing metabolic activities of microorganisms to improve biodegradation processes.
Article
Microbiology
Saeed Niazi Vahdati, Hossein Behboudi, Sepideh Aliniaye Navasatli, Sara Tavakoli, Maliheh Safavi
Summary: Biofilms are complex aggregates of microbes that are protected by an extracellular matrix. D-amino acids have been discovered to inhibit biofilm formation by interfering with different mechanisms, and can be used in combination with other antimicrobial agents to combat bacterial biofilms without toxicity on human cells.
MICROBIOLOGICAL RESEARCH
(2022)
Review
Clinical Neurology
Sofiati Dian, Ahmad Rizal Ganiem, Lindsey H. M. te Brake, Arjan van Laarhoven
Summary: Neurotuberculosis is the most severe form of tuberculosis with a high mortality rate. Early treatment is crucial, but diagnosing and treating neurotuberculosis remains challenging. New antibiotic regimens and host-directed therapies are being studied to combat drug resistance and improve patient outcomes.
Article
Allergy
Kanika Kanchan, Selene Clay, Haritz Irizar, Supinda Bunyavanich, Rasika A. Mathias
Summary: Food allergy is a growing public health burden in the United States, with strong roles for both genes and environment in FA risk. Current genetic association studies reveal a set of genetic loci, genes, and variants that implicate the importance of barrier and immune function genes.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2021)
Article
Energy & Fuels
Katherine J. Davis, Elliott P. Barnhart, Matthew W. Fields, Robin Gerlach
Article
Engineering, Environmental
Neerja M. Zambare, Ellen G. Lauchnor, Robin Gerlach
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2019)
Article
Chemistry, Multidisciplinary
Johannes Hommel, Arda Akyel, Zachary Frieling, Adrienne J. Phillips, Robin Gerlach, Alfred B. Cunningham, Holger Class
APPLIED SCIENCES-BASEL
(2020)
Article
Engineering, Multidisciplinary
Benjamin D. Jackson, James M. Connolly, Robin Gerlach, Isaac Klapper, Albert E. Parker
Summary: This study introduces a novel model for urea consumption in biofilms, allowing different kinetics and comparing the Bayesian and nonlinear least squares methods. Application of the model to synthetic and real data demonstrates potential for general biofilm kinetic information applications.
INVERSE PROBLEMS IN SCIENCE AND ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Hannah D. Schweitzer, Heidi J. Smith, Elliott P. Barnhart, Luke J. McKay, Robin Gerlach, Alfred B. Cunningham, Rex R. Malmstrom, Danielle Goudeau, Matthew W. Fields
Summary: This study investigates the potential genes and functional groups involved in hydrocarbon degradation to methane in coal seams from the Powder River Basin using environmentally relevant metagenomes and BONCAT-FACS derived translationally active metagenomes. The results reveal the presence of biosurfactants, aerobic dioxygenases, and anaerobic phenol degradation pathways in the active populations across the sampled coal seams.
NPJ BIOFILMS AND MICROBIOMES
(2022)
Article
Engineering, Chemical
Felix Weinhardt, Jingxuan Deng, Johannes Hommel, Samaneh Vahid Dastjerdi, Robin Gerlach, Holger Steeb, Holger Class
Summary: Enzymatically induced calcium carbonate precipitation is a promising geotechnique that can be used to seal leakage pathways in the subsurface or stabilize soils. The location of precipitates is more relevant to the hydraulic response in quasi-1D structures, while flow can bypass clogged regions in quasi-2D structures, leading to steadier porosity-permeability relationships. Different polymorphs of calcium carbonate and their influence on preferential flow paths have not been fully considered in existing approaches for porosity-permeability relationships.
TRANSPORT IN POROUS MEDIA
(2022)
Review
Biology
Syeda Tasmia Asma, Kalman Imre, Adriana Morar, Viorel Herman, Ulas Acaroz, Hamid Mukhtar, Damla Arslan-Acaroz, Syed Rizwan Ali Shah, Robin Gerlach
Summary: Biofilm formation on surfaces by microbial colonization is a global health issue that causes infections and provides resistance to treatment. Effective anti-biofilm strategies are necessary to reduce healthcare problems associated with biofilms.
Article
Computer Science, Interdisciplinary Applications
Marnie J. Feder, Arda Akyel, Vincent J. Morasko, Robin Gerlach, Adrienne J. Phillips
Summary: The study investigates the impact of temperature on ureolysis rate and plant-sourced urease inactivation, finding that jack bean meal has the highest activity at 30 degrees C. A model was used to describe urea hydrolysis and enzyme inactivation processes with temperature, showing rapid inactivation of jack bean meal urease at 80 degrees C.
ENGINEERING REPORTS
(2021)
Article
Environmental Sciences
Simon Emmert, Katherine Davis, Robin Gerlach, Holger Class
Review
Microbiology
Luis Zea, Robert J. C. McLean, Tony A. Rook, Geoffrey Angle, D. Layne Carter, Angela Delegard, Adrian Denvir, Robin Gerlach, Sridhar Gorti, Doug McIlwaine, Mononita Nur, Brent M. Peyton, Philip S. Stewart, Paul Sturman, Yo Ann Velez Justiniano
Article
Ecology
Andrew C. Mitchell, Erika J. Espinosa-Ortiz, Stacy L. Parks, Adrienne J. Phillips, Alfred B. Cunningham, Robin Gerlach