Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
出版年份 2018 全文链接
标题
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
作者
关键词
-
出版物
NATURE MEDICINE
Volume 25, Issue 1, Pages 152-164
出版商
Springer Nature
发表日期
2018-11-28
DOI
10.1038/s41591-018-0223-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
- (2018) Michael J. Gandal et al. SCIENCE
- A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease
- (2017) Nicholas T. Seyfried et al. Cell Systems
- Catastrophic cliffs: a partial suggestion for selective vulnerability in neurodegenerative diseases
- (2016) John Hardy BIOCHEMICAL SOCIETY TRANSACTIONS
- Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation
- (2016) Hansen Lui et al. CELL
- Expression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice
- (2016) Sumihiro Maeda et al. EMBO REPORTS
- Genome-wide changes in lncRNA, splicing and regional gene expression patterns in autism
- (2016) Neelroop N. Parikshak et al. NATURE
- Gene expression elucidates functional impact of polygenic risk for schizophrenia
- (2016) Menachem Fromer et al. NATURE NEUROSCIENCE
- Molecular Genetics of Neurodegenerative Dementias
- (2016) Flora I. Hinz et al. Cold Spring Harbor Perspectives in Biology
- Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
- (2016) Karpagam Srinivasan et al. Nature Communications
- MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations
- (2016) Md Helal U. Biswas et al. Stem Cell Reports
- Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
- (2016) Mariet Allen et al. Scientific Data
- Convergent genetic and expression data implicate immunity in Alzheimer's disease
- (2015) Lesley Jones et al. Alzheimers & Dementia
- Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders
- (2015) Smriti Gupta et al. DRUG DEVELOPMENT RESEARCH
- Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
- (2015) Mercedes Prudencio et al. NATURE NEUROSCIENCE
- Canonical genetic signatures of the adult human brain
- (2015) Michael Hawrylycz et al. NATURE NEUROSCIENCE
- Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders
- (2015) Neelroop N. Parikshak et al. NATURE REVIEWS GENETICS
- Tau and neurodegenerative disease: the story so far
- (2015) Khalid Iqbal et al. Nature Reviews Neurology
- Pathological Tau Disrupts Ongoing Network Activity
- (2015) Noa Menkes-Caspi et al. NEURON
- Invited review: Neuropathology of tauopathies: principles and practice
- (2015) G. G. Kovacs NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology
- (2015) Mar Matarin et al. Cell Reports
- Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment
- (2015) Daniel S. Weitzner et al. Jove-Journal of Visualized Experiments
- Alzheimer's disease
- (2015) Colin L. Masters et al. Nature Reviews Disease Primers
- Frontotemporal dementia: a bridge between dementia and neuromuscular disease
- (2014) Adeline S.L. Ng et al. Annals of the New York Academy of Sciences
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity
- (2014) Maike Jaworski et al. EMBO JOURNAL
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Frontotemporal dementia and its subtypes: a genome-wide association study
- (2014) Raffaele Ferrari et al. LANCET NEUROLOGY
- Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
- (2014) Jürgen Cox et al. MOLECULAR & CELLULAR PROTEOMICS
- Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
- (2014) M. Narayanan et al. Molecular Systems Biology
- Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice
- (2014) Tomohiro Onishi et al. NEUROSCIENCE RESEARCH
- A Conserved BDNF, Glutamate- and GABA-Enriched Gene Module Related to Human Depression Identified by Coexpression Meta-Analysis and DNA Variant Genome-Wide Association Studies
- (2014) Lun-Ching Chang et al. PLoS One
- Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer’s Disease
- (2014) Paul D. Wes et al. PLoS One
- Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
- (2014) Scott J. Webster et al. Frontiers in Genetics
- Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism
- (2013) Neelroop N. Parikshak et al. CELL
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
- (2013) Christopher J Lessard et al. NATURE GENETICS
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Treatment of HCV Infection by Targeting MicroRNA
- (2013) Harry L.A. Janssen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Animal Models of Alzheimer Disease
- (2013) F. M. LaFerla et al. Cold Spring Harbor Perspectives in Medicine
- Alzheimer's therapeutics: Continued clinical failures question the validity of the amyloid hypothesis—but what lies beyond?
- (2012) Kevin Mullane et al. BIOCHEMICAL PHARMACOLOGY
- GO-Elite: a flexible solution for pathway and ontology over-representation
- (2012) Alexander C. Zambon et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Removing technical variability in RNA-seq data using conditional quantile normalization
- (2012) K. D. Hansen et al. BIOSTATISTICS
- Neuroligin-1 induces neurite outgrowth through interaction with neurexin-1β and activation of fibroblast growth factor receptor-1
- (2012) Michelle D. Gjørlund et al. FASEB JOURNAL
- Long-term, efficient inhibition of microRNA function in mice using rAAV vectors
- (2012) Jun Xie et al. NATURE METHODS
- Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects
- (2012) Sandra Almeida et al. Cell Reports
- GC-Content Normalization for RNA-Seq Data
- (2011) Davide Risso et al. BMC BIOINFORMATICS
- The Human Brain in a Dish: The Promise of iPSC-Derived Neurons
- (2011) Ricardo Dolmetsch et al. CELL
- Transcriptomic analysis of autistic brain reveals convergent molecular pathology
- (2011) Irina Voineagu et al. NATURE
- Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
- (2011) Günter U Höglinger et al. NATURE GENETICS
- Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain
- (2011) Alexandre Kuhn et al. NATURE METHODS
- miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
- (2011) Marc R. Friedländer et al. NUCLEIC ACIDS RESEARCH
- Is My Network Module Preserved and Reproducible?
- (2011) Peter Langfelder et al. PLoS Computational Biology
- Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
- (2011) Elizabeth J. Rossin et al. PLoS Genetics
- Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma
- (2010) Douglas D. Young et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways
- (2010) Jeremy A. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now