Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control
出版年份 2018 全文链接
标题
Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control
作者
关键词
-
出版物
NATURE
Volume 563, Issue 7731, Pages 407-411
出版商
Springer Nature America, Inc
发表日期
2018-10-31
DOI
10.1038/s41586-018-0678-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hsp40/70/110 chaperones adapt nuclear protein quality control to serve cytosolic clients
- (2018) Rupali Prasad et al. JOURNAL OF CELL BIOLOGY
- A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders
- (2018) Arlene J. George et al. Frontiers in Genetics
- In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome
- (2017) Hikaru Tsuchiya et al. MOLECULAR CELL
- Novel UBQLN2 mutations linked to amyotrophic lateral sclerosis and atypical hereditary spastic paraplegia phenotype through defective HSP70-mediated proteolysis
- (2017) Elisa Teyssou et al. NEUROBIOLOGY OF AGING
- Ubiquitin Accumulation on Disease Associated Protein Aggregates Is Correlated with Nuclear Ubiquitin Depletion, Histone De-Ubiquitination and Impaired DNA Damage Response
- (2017) Adi Ben Yehuda et al. PLoS One
- The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy
- (2017) Yong Tae Kwon et al. TRENDS IN BIOCHEMICAL SCIENCES
- Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis
- (2017) Vibhuti Joshi et al. Frontiers in Cellular Neuroscience
- Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus
- (2017) Yongwang Zhong et al. eLife
- Disturbance of proteasomal and autophagic protein degradation pathways by amyotrophic lateral sclerosis-linked mutations in ubiquilin 2
- (2016) Mayuko Osaka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome
- (2016) Roland Hjerpe et al. CELL
- Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation
- (2016) Ingo Amm et al. FEBS LETTERS
- The increasing complexity of the ubiquitin code
- (2016) Richard Yau et al. NATURE CELL BIOLOGY
- Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models
- (2016) Teemu Natunen et al. NEUROBIOLOGY OF DISEASE
- The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
- (2016) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- In vivo aspects of protein folding and quality control
- (2016) D. Balchin et al. SCIENCE
- Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome
- (2016) Xiang Chen et al. STRUCTURE
- Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system
- (2015) L. Ulbrich et al. BIOCHEMICAL JOURNAL
- Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition
- (2015) S. B. Miller et al. EMBO JOURNAL
- Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3
- (2015) Li Zeng et al. NEUROBIOLOGY OF DISEASE
- Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids
- (2014) Julian Stevenson et al. BIOCHEMICAL JOURNAL
- The ubiquilin gene family: evolutionary patterns and functional insights
- (2014) Ignacio Marín BMC EVOLUTIONARY BIOLOGY
- The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway
- (2014) N. Zelcer et al. MOLECULAR AND CELLULAR BIOLOGY
- Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells
- (2014) Nils A Kulak et al. NATURE METHODS
- PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone
- (2013) Sae-Hun Park et al. CELL
- Hsp70 Targets a Cytoplasmic Quality Control Substrate to the San1p Ubiquitin Ligase
- (2013) Christopher J. Guerriero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting
- (2013) Ayala Shiber et al. MOLECULAR BIOLOGY OF THE CELL
- Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
- (2013) Stéphanie Escusa-Toret et al. NATURE CELL BIOLOGY
- The Type II Hsp40 Sis1 Cooperates with Hsp70 and the E3 Ligase Ubr1 to Promote Degradation of Terminally Misfolded Cytosolic Protein
- (2013) Daniel W. Summers et al. PLoS One
- Ubiquilin-1 and protein quality control in Alzheimer disease
- (2013) Amina El Ayadi et al. Prion
- Disrupted in Schizophrenia 1 forms pathological aggresomes that disrupt its function in intracellular transport
- (2012) Talia A. Atkin et al. HUMAN MOLECULAR GENETICS
- Subcellular Distribution and Dynamics of Active Proteasome Complexes Unraveled by a Workflow Combiningin VivoComplex Cross-Linking and Quantitative Proteomics
- (2012) Bertrand Fabre et al. MOLECULAR & CELLULAR PROTEOMICS
- Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates
- (2012) Liliana Malinovska et al. MOLECULAR BIOLOGY OF THE CELL
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- Neuroligin Trafficking Deficiencies Arising from Mutations in the α/β-Hydrolase Fold Protein Family
- (2010) Antonella De Jaco et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Nucleus-based Quality Control Mechanism for Cytosolic Proteins
- (2010) Rupali Prasad et al. MOLECULAR BIOLOGY OF THE CELL
- Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1
- (2010) E Fujita et al. Cell Death & Disease
- Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation
- (2009) Ping Xu et al. CELL
- Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1
- (2009) J. W. Heck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex
- (2008) Lingyan Jin et al. CELL
- Trafficking of cholinesterases and neuroligins mutant proteins
- (2008) Antonella De Jaco et al. CHEMICO-BIOLOGICAL INTERACTIONS
- A Destructive Interaction Mechanism Accounts for Dominant-Negative Effects of Misfolded Mutants of Voltage-Gated Calcium Channels
- (2008) A. Mezghrani et al. JOURNAL OF NEUROSCIENCE
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started