Parkinsonism due to A53E α-synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

(2017) Yvette C Wong et al.   NATURE MEDICINE

SNCA mutation p.Ala53Glu is derived from a common founder in the Finnish population

(2017) Petra Pasanen et al.   NEUROBIOLOGY OF AGING

The correlation of methylation levels measured using Illumina 450K and EPIC BeadChips in blood samples

(2017) Mark W Logue et al.   Epigenomics

Motor and Nonmotor Features of Carriers of the p.A53T Alpha-Synuclein Mutation: A Longitudinal Study

(2016) Dimitra Papadimitriou et al.   MOVEMENT DISORDERS

The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation

(2016) Diana F. Lázaro et al.   Acta Neuropathologica Communications

Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization

(2015) Filsy Samuel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutation analysis of patients with neurodegenerative disorders using NeuroX array

(2015) Mahdi Ghani et al.   NEUROBIOLOGY OF AGING

The A53E α-synuclein pathological mutation demonstrates reduced aggregation propensity in vitro and in cell culture

(2015) Nicola J. Rutherford et al.   NEUROSCIENCE LETTERS

The Newly Discovered Parkinson’s Disease Associated Finnish Mutation (A53E) Attenuates α-Synuclein Aggregation and Membrane Binding

(2014) Dhiman Ghosh et al.   BIOCHEMISTRY

A novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology

(2014) Petra Pasanen et al.   NEUROBIOLOGY OF AGING

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

α-Synuclein oligomers and clinical implications for Parkinson disease

(2012) Lorraine V. Kalia et al.   ANNALS OF NEUROLOGY

Cardiac sympathetic denervation in symptomatic and asymptomatic carriers of the E46K mutation in the α synuclein gene

(2012) Beatriz Tijero et al.   PARKINSONISM & RELATED DISORDERS

Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5)

(2011) Lorraine V. Kalia et al.   PLoS One

Phosphorylation of Synucleins by Members of the Polo-like Kinase Family

(2009) Martial K. Mbefo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY