A highly efficient precatalytic system (XPhos-PdG2) for the Suzuki–Miyaura cross-coupling of 7-chloro-1H-pyrrolo[2,3-c]pyridine employing low catalyst loading

Microwave-Assisted Decarbonylative Coupling Reaction of o-Halobenzamides for Phenanthridinone Synthesis

(2018) Xuwen Chen et al.   ChemistrySelect

A Highly Efficient Catalyst for the Suzuki-Miyaura Cross-Coupling Reaction of 5-(5-chloropyridin-3-yl)-3-methyl-1,3,4-oxadiazol-2(3H )-one

(2018) Bhaskaran Savitha et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Direct Synthesis of Methylene-Bridged Bis-biaryl Carboxylates via Cascade Suzuki Coupling and CH2 Cl2 -Based Bis-esterification

(2018) Jin Xiong et al.   ChemistrySelect

Novel tacrine derivatives exhibiting improved acetylcholinesterase inhibition: Design, synthesis and biological evaluation

(2017) Eeda Koti Reddy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Solvent and Base in One: Tetra-n -butylammonium Acetate as a Multi-Purpose Ionic Liquid Medium for Ru-Catalyzed Directed Mono- and Di-o -C-H Arylation Reactions

(2017) Ya-Ling Zou et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Polyflourinated Biphenyls; Pushing the Boundaries of Suzuki–Miyaura Cross Coupling with Electron-Poor Substrates

(2017) David Bulfield et al.   JOURNAL OF ORGANIC CHEMISTRY

Integrated Pd-catalyzed cross-coupling strategies for furnishing α-carbolines

(2017) Misayo Sera et al.   TETRAHEDRON

NMI/MsCl-Mediated Amide Bond Formation of Aminopyrazines and Aryl/Heteroaryl Carboxylic Acids: Synthesis of Biologically Relevant Pyrazine Carboxamides.

(2017) Nagaraja Reddy Gangarapu et al.   ChemistrySelect

Simultaneous exploration of TBAF·3H 2 O as a base as well as a solvating agent for the palladium catalyzed Suzuki cross-coupling of 4-methyl-7-nonafluorobutylsulfonyloxy coumarins under microwave irradiation

(2016) M. Nibin Joy et al.   JOURNAL OF FLUORINE CHEMISTRY

A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors

(2016) A. Hooper et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Substituted 4-, 5-, 6-, and 7-Azaindoles from Aminopyridines via a Cascade C–N Cross-Coupling/Heck Reaction

(2016) Marina J. D. Pires et al.   ORGANIC LETTERS

Dichloromethane as methylene donor for the one-pot synthesis of bisaryloxy methanes via Williamson etherification and Suzuki coupling

(2016) Xuwen Chen et al.   TETRAHEDRON LETTERS

Functionalised dihydroazo pyrimidine derivatives from Morita–Baylis–Hillman acetates: synthesis and studies against acetylcholinesterase as its inhibitors

(2016) Eeda Koti Reddy et al.   RSC Advances

Facile Synthesis of Fully Decorated Imidazo[4,5-b] and Imidazo[4,5-c] Pyridines in Aqueous DMF via C-H Activation under Microwave Irradiation

(2016) Mr. P. Avinesh  et al.   ChemistrySelect

Suzuki-Miyaura cross-coupling reaction in water: facile synthesis of (hetero) aryl uracil bases using potassiumorganotrifluoroborates under microwave irradiation.

(2016) Bhaskaran Savitha et al.   ChemistrySelect

Design, synthesis and structure–activity relationship (SAR) studies of imidazo[4,5-b]pyridine derived purine isosteres and their potential as cytotoxic agents

(2015) Ayyiliath M. Sajith et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2-Aminobiphenyl Palladacycles: The “Most Powerful” Precatalysts in C–C and C–Heteroatom Cross-Couplings

(2015) Alexandre Bruneau et al.   ACS Catalysis

The Azaindole Framework in the Design of Kinase Inhibitors

(2014) Jean-Yves Mérour et al.   MOLECULES

Structure-based de novo design and identification of D816V mutant-selective c-KIT inhibitors

(2014) Hwangseo Park et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A rapid approach for the copper, amine, and ligand-free Sonogashira coupling of 4-methyl-7-nonafluorobutylsulfonyloxy coumarins under microwave irradiation

(2014) M. Nibin Joy et al.   TETRAHEDRON LETTERS

A rapid and modified approach for C-7 amination and amidation of 4-methyl-7-nonafluorobutylsulfonyloxy coumarins under microwave irradiation

(2014) M. Nibin Joy et al.   RSC Advances

Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode

(2013) Venkateshwar Rao Gummadi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The optimization of aminooxadiazoles as orally active inhibitors of Cdc7

(2013) Paul E. Harrington et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Suzuki-Miyaura Cross-Coupling of Unprotected, Nitrogen-Rich Heterocycles: Substrate Scope and Mechanistic Investigation

(2013) M. Alexander Düfert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cycloalkenyl nonaflates as electrophilic cross-coupling substrates for palladium catalyzed C–N bond forming reactions with enolizable heterocycles under microwave enhanced conditions

(2013) K. K. Abdul Khader et al.   NEW JOURNAL OF CHEMISTRY

A facile access to substituted indoles utilizing palladium catalyzed annulation under microwave enhanced conditions

(2013) Ranjith P. Karuvalam et al.   TETRAHEDRON LETTERS

Mild and General Conditions for Negishi Cross-Coupling Enabled by the Use of Palladacycle Precatalysts

(2012) Yang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scope of the Two-Step, One-Pot Palladium-Catalyzed Borylation/Suzuki Cross-Coupling Reaction Utilizing Bis-Boronic Acid

(2012) Gary A. Molander et al.   JOURNAL OF ORGANIC CHEMISTRY

Rapid, microwave-assisted organic synthesis of selective V600EBRAF inhibitors for preclinical cancer research

(2012) Jason R. Buck et al.   TETRAHEDRON LETTERS

Exploration of copper and amine-free Sonogashira cross coupling reactions of 2-halo-3-alkyl imidazo[4,5-b]pyridines using tetrabutyl ammonium acetate as an activator under microwave enhanced conditions

(2012) Ayyiliath M. Sajith et al.   TETRAHEDRON LETTERS

Synthesis and Anti-inflammatory Evaluation of Novel Benzimidazole and Imidazopyridine Derivatives

(2012) Gaozhi Chen et al.   ACS Medicinal Chemistry Letters

Microwave enhanced Suzuki coupling: a diversity-oriented approach to the synthesis of highly functionalised 3-substituted-2-aryl/heteroaryl imidazo[4,5-b]pyridines

(2011) Ayyiliath M. Sajith et al.   TETRAHEDRON LETTERS

Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells

(2010) Nathalie Bouloc et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and structure–activity relationships of novel biarylamine-based Met kinase inhibitors

(2010) David K. Williams et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Palladium-Catalyzed Amination of Unprotected Halo-7-azaindoles

(2010) Jaclyn L. Henderson et al.   ORGANIC LETTERS

A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors

(2009) Tiansheng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Negishi Cross-Couplings Compatible with Unprotected Amide Functions

(2009) Georg Manolikakes et al.   CHEMISTRY-A EUROPEAN JOURNAL

Discovery and Development of Aurora Kinase Inhibitors as Anticancer Agents

(2009) John R. Pollard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Pyrrolopyridine−Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities

(2008) Kyoung Soon Kim et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium- and Nickel-Catalyzed Cross-Couplings of Unsaturated Halides Bearing Relatively Acidic Protons with Organozinc Reagents

(2008) Georg Manolikakes et al.   JOURNAL OF ORGANIC CHEMISTRY

Negishi Cross-Couplings of Unsaturated Halides Bearing Relatively Acidic Hydrogen Atoms with Organozinc Reagents

(2008) Georg Manolikakes et al.   ORGANIC LETTERS