Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms

Potential Use of Nanomedicine for the Anti-inflammatory Treatment of Neurodegenerative Diseases

(2018) Maria Dolores Cayero-Otero et al.   CURRENT PHARMACEUTICAL DESIGN

Soy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects

(2018) Seyed-Mohamad-Sadegh Mirahmadi et al.   CYTOKINE

Naringenin ameliorates learning and memory impairment following systemic lipopolysaccharide challenge in the rat

(2018) Mohammad-Reza Khajevand-Khazaei et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats

(2018) Hend M. Hussien et al.   FOOD AND CHEMICAL TOXICOLOGY

Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines

(2018) Solmaz Nasseri Maleki et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Protective effects of Alpinae Oxyphyllae Fructus extracts on lipopolysaccharide-induced animal model of Alzheimer's disease

(2018) Yunlong Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice

(2018) Jing Zhang et al.   Journal of Neuroinflammation

Supplementation of lycopene attenuates lipopolysaccharide-induced amyloidogenesis and cognitive impairments via mediating neuroinflammation and oxidative stress

(2018) Jia Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Neuroprotective effect of berberine agonist against impairment of learning and memory skills in severe traumatic brain injury via Sirt1/p38 MAPK expression

(2018) Jianping Wang et al.   Molecular Medicine Reports

Multiple Immune-Inflammatory and Oxidative and Nitrosative Stress Pathways Explain the Frequent Presence of Depression in Multiple Sclerosis

(2018) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation

(2018) Shu-Xuan Huang et al.   NEUROCHEMICAL RESEARCH

Pretreatment With Risperidone Ameliorates Systemic LPS-Induced Oxidative Stress in the Cortex and Hippocampus

(2018) Md. Mamun Al-Amin et al.   Frontiers in Neuroscience

S-allyl cysteine ameliorates cognitive deficits in streptozotocin-diabetic rats via suppression of oxidative stress, inflammation, and acetylcholinesterase

(2017) Tourandokht Baluchnejadmojarad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms

(2017) Mahboubeh Zarezadeh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

N-Stearoylethanolamine protects the brain and improves memory of mice treated with lipopolysaccharide or immunized with the extracellular domain of α7 nicotinic acetylcholine receptor

(2017) Olena Lykhmus et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice

(2017) Mengmeng Li et al.   Journal of Neuroinflammation

Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice

(2017) Amrita A. Chowdhury et al.   METABOLIC BRAIN DISEASE

A Possible Anti-Inflammatory Effect of Proline in the Brain Cortex and Cerebellum of Rats

(2017) Vivian Strassburger Andrade et al.   MOLECULAR NEUROBIOLOGY

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

The role of BDNF in Alzheimer's disease

(2017) Heikki Tanila   NEUROBIOLOGY OF DISEASE

Neuroprotective effect of berberine against learning and memory deficits in diffuse axonal injury

(2017) Hong‑Cai Wang et al.   Experimental and Therapeutic Medicine

Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)-Induced Oxidative Stress to Rescue Postnatal Rat Brain

(2016) Shahid Ali Shah et al.   CNS Neuroscience & Therapeutics

Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade

(2016) Ashok Jangra et al.   INFLAMMATION

Anthocyanins control neuroinflammation and consequent memory dysfunction in mice exposed to lipopolysaccharide

(2016) Fabiano B. Carvalho et al.   MOLECULAR NEUROBIOLOGY

Tempol and perindopril protect against lipopolysaccharide-induced cognition impairment and amyloidogenesis by modulating brain-derived neurotropic factor, neuroinflammation and oxido-nitrosative stress

(2016) Mohammed Ragab Abdel-Aziz Ali et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

Berberine up-regulates the BDNF expression in hippocampus and attenuates corticosterone-induced depressive-like behavior in mice

(2016) Ji-duo Shen et al.   NEUROSCIENCE LETTERS

Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1

(2016) Liming Yu et al.   Oxidative Medicine and Cellular Longevity

Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms

(2016) Siamak Ahshin-Majd et al.   PEPTIDES

Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis

(2016) Liang Liu et al.   Oncotarget

Molecular Mechanisms Regulating LPS-Induced Inflammation in the Brain

(2016) Olena Lykhmus et al.   Frontiers in Molecular Neuroscience

Systemic lipopolysaccharide administration impairs retrieval of context–object discrimination, but not spatial, memory: Evidence for selective disruption of specific hippocampus-dependent memory functions during acute neuroinflammation

(2015) Jennifer Czerniawski et al.   BRAIN BEHAVIOR AND IMMUNITY

Spermine reverses lipopolysaccharide-induced memory deficit in mice

(2015) Pâmella Frühauf et al.   Journal of Neuroinflammation

Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway

(2015) Sun Mi Gu et al.   Journal of Neuroinflammation

The neuroprotective effect of berberine in mercury-induced neurotoxicity in rats

(2015) Ahmed E. Abdel Moneim   METABOLIC BRAIN DISEASE

Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF

(2015) Roman Fischer et al.   Oxidative Medicine and Cellular Longevity

Antidiabetic potential of salvianolic acid B in multiple low-dose streptozotocin-induced diabetes

(2015) Safoura Raoufi et al.   PHARMACEUTICAL BIOLOGY

Protective effect of berberine, an isoquinoline alkaloid ameliorates ethanol-induced oxidative stress and memory dysfunction in rats

(2015) Shaktipal Patil et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Therapeutic potential of berberine against neurodegenerative diseases

(2015) WenXiao Jiang et al.   Science China-Life Sciences

Long-term sequelae of severe sepsis: cognitive impairment and structural brain alterations – an MRI study (LossCog MRI)

(2014) Theresa Götz et al.   BMC Neurology

Berberine prevents nigrostriatal dopaminergic neuronal loss and suppresses hippocampal apoptosis in mice with Parkinson’s disease

(2014) MIA KIM et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment

(2014) Andrea R Vasconcelos et al.   Journal of Neuroinflammation

Long-term cerebral consequences of sepsis

(2014) Catherine N Widmann et al.   LANCET NEUROLOGY

Activated Microglia-Induced Deficits in Excitatory Synapses Through IL-1β: Implications for Cognitive Impairment in Sepsis

(2014) Carolina A. Moraes et al.   MOLECULAR NEUROBIOLOGY

Chronic lipopolysaccharide exposure induces cognitive dysfunction without affecting BDNF expression in the rat hippocampus

(2014) BIN ZHU et al.   Experimental and Therapeutic Medicine

Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis

(2013) Robert Domitrović et al.   FOOD AND CHEMICAL TOXICOLOGY

Anti-Inflammatory Effect of Ginsenoside Rg5 in Lipopolysaccharide-Stimulated BV2 Microglial Cells

(2013) Yu Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Berberine Ameliorate Oxidative Stress and Astrogliosis in the Hippocampus of STZ-Induced Diabetic Rats

(2013) Hamid Kalalian Moghaddam et al.   MOLECULAR NEUROBIOLOGY

Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats

(2013) L.-W. Fan et al.   NEUROSCIENCE

Attenuation of berberine on lipopolysaccharide-induced inflammatory and apoptosis responses in β-cells via TLR4-independent JNK/NF-κB pathway

(2013) Ying Wang   PHARMACEUTICAL BIOLOGY

Chronic Pravastatin but Not Atorvastatin Treatment Impairs Cognitive Function in Two Rodent Models of Learning and Memory

(2013) Sarah A. Stuart et al.   PLoS One

Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats

(2013) Xiang-Shan Tan et al.   PLoS One

Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala

(2011) Ryota Haba et al.   BEHAVIOURAL BRAIN RESEARCH

Hesperetin, a citrus flavonone, protects potentially cadmium induced oxidative testicular dysfunction in rats

(2011) Kalist Shagirtha et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effect of melatonin on neuroinflammation and acetylcholinesterase activity induced by LPS in rat brain

(2010) Ethika Tyagi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress

(2010) Ying Qiao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation

(2010) Claudia Patrignani et al.   Journal of Inflammation-London

Neuroinflammation and Cognitive Aging

(2010) Raymond L. Ownby   Current Psychiatry Reports

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

(2008) Christopher J Henry et al.   Journal of Neuroinflammation