4.6 Article

Women Experience the Same Ergogenic Response to Caffeine as Men

期刊

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
卷 51, 期 6, 页码 1195-1202

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/MSS.0000000000001885

关键词

EXERCISE PERFORMANCE; ERGOGENIC AIDS; CENTRAL NERVOUS SYSTEM STIMULANTS; PHYSIOLOGICAL EFFECTS OF DRUGS; SEX DIFFERENCES

资金

  1. University of Queensland New Staff Research Start-Up Fund [2011001239]

向作者/读者索取更多资源

Purpose This study aimed to determine whether 1) consumption of caffeine improves endurance cycling performance in women and 2) sex differences exist in the magnitude of the ergogenic and plasma responses to caffeine supplementation. Methods Twenty-seven (11 women and 16 men) endurance-trained cyclists and triathletes participated in this randomized, double-blind, placebo-controlled, crossover study. Participants completed an incremental exercise test to exhaustion, two familiarization trials, and two performance trials. Ninety minutes before the performance trials, participants ingested opaque capsules containing either 3 mg center dot kg(-1) body mass of anhydrous caffeine or a placebo. They then completed a set amount of work (75% of peak sustainable power output) in the fastest possible time. Plasma was sampled at baseline, preexercise, and postexercise for caffeine. Strict standardization and verification of diet, hydration, training volume and intensity, and contraceptive hormone phase (for women) were implemented. Results Performance time was significantly improved after caffeine administration in women (placebo: 3863 +/- 419 s, caffeine: 3757 +/- 312 s; P = 0.03) and men (placebo: 3903 +/- 341 s, caffeine: 3734 +/- 287 s; P < 0.001). The magnitude of performance improvement was similar for women (mean = 4.3%, 95% CI = 0.4%-8.2%) and men (4.6%, 2.3%-6.8%). Plasma caffeine concentrations were similar between sexes before exercise, but significantly greater in women after exercise (P < 0.001). Conclusions Ingestion of 3 mg center dot kg(-1) body mass of caffeine enhanced endurance exercise performance in women. The magnitude of the performance enhancement observed in women was similar to that of men, despite significantly greater plasma caffeine concentrations after exercise in women. These results suggest that the current recommendations for caffeine intake (i.e., 3-6 mg center dot kg(-1) caffeine before exercise to enhance endurance performance), which are derived almost exclusively from studies on men, may also be applicable to women.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Physiology

The effect of exercise hyperpnea on gross efficiency and anaerobic capacity estimates during a 3-min cycle time trial

Erik P. Andersson, Thomas L. Stoggl, Philipp Bachl, John O. Osborne

Summary: This study aimed to analyze the effect of exercise-induced hyperpnea on gross efficiency (GE) and anaerobic capacity estimates during a self-paced 3-min supramaximal cycle time trial (TT). The study found that the hyperpnea-corrected models generated lower GE and higher anaerobic capacity during the supramaximal TT, compared to the conventional models. The linear models for estimating anaerobic capacity are likely to generate underestimated values.

JOURNAL OF APPLIED PHYSIOLOGY (2023)

Article Medicine, General & Internal

Emergency department presentations during the COVID-19 pandemic in Queensland (to June 2021): interrupted time series analysis

Amy L. Sweeny, Gerben Keijzers, Andrea Marshall, Emma J. Hall, Jamie Ranse, Ping Zhang, Gary Grant, Ya-Ling Huang, Dinesh Palipana, Yang D. Teng, Benjamin Gerhardy, Jaimi H. Greenslade, Philip Jones, Julia L. Crilly

Summary: This study assessed the number of emergency department (ED) presentations in Queensland during the low COVID-19 case period of 2020-2021. The analysis showed a 19.4% decrease in ED presentations during the lockdown period compared to the pre-pandemic period. The decline varied across different triage categories and diagnostic groups, with presentations for less urgent conditions and mental health problems remaining below predicted levels in the post-lockdown period.

MEDICAL JOURNAL OF AUSTRALIA (2023)

Review Hospitality, Leisure, Sport & Tourism

A review exploring coach knowledge, attitudes/beliefs and behaviours towards low energy availability in athletes

Jennifer Hamer, Ben Desbrow, Chris Irwin

Summary: Coaches play a crucial role in athlete health and performance, but their knowledge, attitudes, and behaviors regarding low energy availability (LEA) are lacking. It is important to investigate coaches' current understanding of LEA to guide future education and support initiatives.

INTERNATIONAL JOURNAL OF SPORTS SCIENCE & COACHING (2023)

Review Pharmacology & Pharmacy

Gamification in pharmacy education: a systematic quantitative literature review

Denise L. Hope, Gary D. Grant, Gary D. Rogers, Michelle A. King

Summary: This article provides a systematic and quantitative review and evaluation of the alignment of learning outcomes and the quality of peer-reviewed literature reporting gamification in pharmacy education. The findings highlight the inconsistent reporting quality, misalignment between intended learning outcomes and reported outcomes, overreliance on student perceptions as primary data, and lack of reference to reporting guidelines. The review identifies evidence gaps and emphasizes the need for improved research quality, alignment of learning outcomes with evaluation, and use of reporting guidelines in gamification studies.

INTERNATIONAL JOURNAL OF PHARMACY PRACTICE (2023)

Review Oncology

Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Christopher T. V. Swain, Ann E. Drummond, Roger L. Milne, Dallas R. English, Kristy A. Brown, Makayla W. C. Lou, Leonessa Boing, Amy Bageley, Tina L. Skinner, Eline H. van Roekel, Melissa M. Moore, Tom R. Gaunt, Richard M. Martin, Sarah J. Lewis, Brigid M. Lynch

Summary: The protective effect of physical activity on breast cancer incidence may be partly mediated by inflammation. Meta-analyses of intervention studies showed that exercise interventions reduced levels of circulating inflammatory biomarkers, providing support for the biological plausibility of the physical activity-inflammation-breast cancer pathway.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2023)

Article Physiology

Neuromuscular electrical stimulation during maximal voluntary contraction: a Delphi survey with expert consensus

J. O. Osborne, J. Tallent, O. Girard, P. W. Marshall, D. Kidgell, R. Buhmann

Summary: This Delphi study aimed to gather expert opinions and provide recommendations for best practices when using electrical stimulation during maximal voluntary contractions. The study found that electrical stimulation can validly assess voluntary activation in specific circumstances, such as during maximal contractions, and can be applied to either the muscle or the nerve. The recommendations from experts in this study can guide researchers in making informed decisions when designing studies involving electrical stimulation for the assessment of voluntary activation.

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2023)

Review Sport Sciences

Long-Term Development of Training Characteristics and Performance-Determining Factors in Elite/International and World-Class Endurance Athletes: A Scoping Review

Hanne C. Staff, Guro Strom Solli, John O. Osborne, Oyvind Sandbakk

Summary: This scoping review identified a limited number of studies that describe the long-term development of training and performance-determining factors in male and female endurance athletes. The findings suggest a non-linear increase in training volume over time and improvements in submaximal variables and maximal performance indices. However, the development of VO2max showed inconsistent results. No evidence was found regarding sex differences in the development of training or performance-determining factors among endurance athletes.

SPORTS MEDICINE (2023)

Review Nutrition & Dietetics

The Effect of Exercise Prescription on the Human Gut Microbiota and Comparison between Clinical and Apparently Healthy Populations: A Systematic Review

Alexander N. Boytar, Tina L. Skinner, Ruby E. Wallen, David G. Jenkins, Marloes Dekker Nitert

Summary: This study systematically reviewed human longitudinal exercise interventions and found that moderate to high-intensity exercise for 30-90 min, at least 3 times per week (or 150-270 min per week) for 8 weeks or more, is likely to produce changes in the gut microbiota. Exercise appears to be effective in modifying the gut microbiota in both clinical and healthy populations. More rigorous methodology is needed for future studies to improve the certainty of the evidence.

NUTRIENTS (2023)

Review Biochemistry & Molecular Biology

The effect of contact/collision sport participation without concussion on neurometabolites: A systematic review and meta-analysis of magnetic resonance spectroscopy studies

Nathan Delang, Christopher Irwin, Aimie L. Peek, Iain S. Mcgregor, Ben Desbrow, Danielle Mccartney

Summary: This study systematically reviewed prior research on the effects of contact/collision sport participation on neurometabolite levels in the absence of concussion. The review found that N-acetylaspartate (NAA) and total creatine (tCr) decreased during the sports season, but glutamate-glutamine (Glx), myo-inositol (mI), and total choline (tCho) did not show significant changes. Several moderating factors, including sex, sport played, brain region, and the MRS quantification approach, were found to influence the results. The study suggests that contact/collision sport participation has the potential to alter neurometabolites measured via H-1 MRS in the absence of concussion, but further research is needed.

JOURNAL OF NEUROCHEMISTRY (2023)

Article Endocrinology & Metabolism

Involvement of indoleamine 2, 3-dioxygenase (IDO) and brain-derived neurotrophic factor (BDNF) in the neuroprotective mechanisms of ferulic acid against depressive-like behaviour

Sanchari Basu Mallik, Jayesh Mudgal, Manas Kinra, Susan Hall, Gary D. Grant, Shailendra Anoopkumar-Dukie, Madhavan Nampoothiri, Yuqing Zhang, Devinder Arora

Summary: The objective of this study was to investigate the neuroprotective mechanisms of ferulic acid (FA) by using a lipopolysaccharide (LPS)-induced depressive-like behavior model. The results indicated that low doses of FA attenuated depressive-like behavior by modulating IDO, BDNF, and reducing neuroinflammation.

METABOLIC BRAIN DISEASE (2023)

Review Infectious Diseases

The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy

Asiyeh Avakh, Gary D. Grant, Matthew J. Cheesman, Tejaswini Kalkundri, Susan Hall

Summary: Pseudomonas aeruginosa (P. aeruginosa) is a problematic bacterium due to its multidrug resistance (MDR) phenotype. It exhibits intrinsic and acquired resistance to many antibiotics, and efflux pumps, particularly the Mex pumps, play a crucial role in driving MDR. Developing efflux pump inhibitors (EPIs) holds great potential for overcoming MDR and restoring the efficacy of antipseudomonal drugs.

ANTIBIOTICS-BASEL (2023)

Review Substance Abuse

A review of factors influencing drinking behaviours in young Australian adults using a behavioural framework approach

Blake Palmer, Christopher Irwin, Ben Desbrow

Summary: Factors influencing alcohol consumption behaviors among young Australian adults include physical and social opportunities, as well as reflective and automatic motivations. The COM-B model provides an integrated understanding of these factors and their impact on drinking behaviors.

DRUG AND ALCOHOL REVIEW (2023)

Review Food Science & Technology

Preparation procedures of food and beverage samples for oxygen bomb calorimetry: A scoping review and reporting checklist

Zane Hopper, Ben Desbrow, Shelley Roberts, Chris Irwin

Summary: Standardised bomb calorimetry methods are crucial for accurately measuring the energy content of food and beverages, but there is currently no universally accepted protocol. This review aims to summarize the literature on sample preparation methods used in bomb calorimetry for food and beverage analysis. The synthesis provides insights into the potential impact of methodological variations on the estimation of caloric values.

JOURNAL OF FOOD AND DRUG ANALYSIS (2023)

Article Public, Environmental & Occupational Health

The availability and promotion of low-alcohol beverages in licensed venues: an environmental audit on the Gold Coast, Australia

Blake Palmer, Christopher Irwin, Christina Mailer, Ben Desbrow

Summary: This study investigated the availability, visibility, advertising, and promotion of low-alcohol beverages (LABs) in licensed venues in Australia. The findings showed that LABs were available in about half of the venues audited, but their visibility and promotion were poor. There is a need to improve access to and promote lower alcohol alternatives within licensed venues.

PUBLIC HEALTH RESEARCH & PRACTICE (2023)

Article Education, Scientific Disciplines

Evaluation of affective learning in a gamified pharmacy simulation

D. L. Hope, G. D. Rogers, G. D. Grant, M. A. King

Summary: The aim of this research was to evaluate affective learning in participants of an extended, immersive, gamified pharmacy simulation. Affective learning was assessed via analysis of student reflective journals. From 2016 to 2018, 123 students participated in the simulation, generating 734 reflective journal entries for analysis. Overall, affective learning was evident, and its level increased over the course of the simulation. This was primarily associated with the improvements of female students.

FOCUS ON HEALTH PROFESSIONAL EDUCATION-A MULTIDISCIPLINARY JOURNAL (2023)

暂无数据