Article
Construction & Building Technology
Yogiraj Sargam, Kejin Wang, Ayuna Tsyrenova, Fei Liu, Shan Jiang
Summary: Different surfactants were used to disperse nanosilica in cement pore solution, with results showing that nonionic surfactants led to improved dispersibility and linear increase in compressive strength of cement-nanosilica pastes. Among all surfactants, Triton X-405 had the highest critical micelle concentration and resulted in the highest strength increase attributed to the nucleation of CSH gel and densification with calcite nanocrystals.
CEMENT AND CONCRETE RESEARCH
(2021)
Article
Chemistry, Physical
Wenning Zhou, Long Jiang, Xunliang Liu, Yang Hu, Yuying Yan
Summary: The study found that mixed surfactants exhibit superior performance by attracting and reducing repulsion between molecules to improve interfacial properties. Controlling the number of ethylene oxide groups can prevent surfactant aggregation and enhance interfacial performance. The positive charge of DTAC molecules shows strong repulsion to salt ions, increasing the overall salt resistance of mixed surfactants.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Polymer Science
Min Su, Yu-Jing Sheng, Yu-Jiao Chen, Tao Li, Quan-Xi Shi, Hang Xiao, Meng-Qin Pu, Hongli Bao, Wen-Ming Wan
Summary: A versatile living polymerization method is reported, which allows the precise synthesis of narrow distributed polystyrenes through the introduction of a well-established all-in-one covalent-anionic-radical Barbier strategy, using a wide variety of organohalides as initiators under mild conditions.
Article
Chemistry, Analytical
Fatemeh Aghaziyarati Farahani, Esmaeel Alipour, Reza Mohammadi, Mohammad Sadegh Amini-Fazl, Khalil Abnous
Summary: The study outlined the method of improving the sensitivity of biomarker detection by optimizing electrochemical signals and successfully developed an aptasensor for detecting trace amounts of myoglobin.
Article
Chemistry, Multidisciplinary
Stephen D. P. Fielden, Matthew J. Derry, Alisha J. Miller, Paul D. Topham, Rachel K. O'Reilly
Summary: Biological cells are surrounded by phospholipid membranes to retain their contents. The fusion of phospholipid membranes mediates the movement of material within and between cells, allowing mixing of contents or excretion of material. While biological membrane fusion is well-studied, the controlled fusion of polymer-based membranes is largely unexplored. In this study, triggered polymersome fusion was demonstrated using out-of-equilibrium polymersomes formed by ring-opening metathesis polymerization-induced self-assembly, which persist until a specific chemical signal triggers their fusion. This research is important for developing communication methods between polymersomes and emulating life-like behaviors in synthetic nanotechnology.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Environmental Sciences
Qingguo Wang, Lina Tuo, Gang Zhou, Yuanyuan Zhang, Xu Geng, Fasong Zhang, Yonghe Li
Summary: The study revealed that adding nonionic silicones to surfactant solutions can effectively reduce surface tension and wetting time, but has varying effects on foam performance. The difference mainly stems from the different electronegativity between the head groups of anionic and nonionic surfactants, affecting the insertion of nonionic silicones in the liquid film, thus altering foam performance.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Physical
Sania Amjad, Saadia Shaukat, Hafiz Muhammad Abd Ur Rahman, Muhammad Usman, Zahoor H. Farooqi, Muhammad Faizan Nazar
Summary: This study focuses on the interaction between cationic dye methylene blue (MB) and anionic surfactant sodium dodecyl sulfate (SDS), as well as its mixed micelles with nonionic surfactant Triton X-114 (TX-114). The results show that the mixed micellar system is more effective in removing and solubilizing MB from aqueous systems. However, an increase in the concentration of the nonionic surfactant weakens the dye-surfactant interaction in the ionic-nonionic mixed micellar system.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Junqing Meng, Lijuan Wang, Shuo Zhang, Yingpei Lyu, Junkai Xia
Summary: Different surfactants have varying effects on the wettability of coal surfaces. Anionic surfactants are effective in improving the wettability of low metamorphic coal, while nonionic surfactants are more effective on high metamorphic coal. The results provide a theoretical basis for the effective application of different surfactants in coal dust control.
CHEMICAL PHYSICS LETTERS
(2021)
Article
Chemistry, Physical
Zhihu Yan, Yanju Wu, Min Zhao, Li Yu, Shibo Zhang
Summary: Gemini surfactants with different hydrophobic tails and spacer groups were designed and synthesized in this study. The structures were verified by 1H NMR spectrum and mass spectrometry. The research discussed the modulation of micellar thermodynamics and surface activity by the molecular structure, and demonstrated the cost-effective evaluation of surface activity using the molecular polarity index (MPI).
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Chemical
Xue Liang, Jun Dong, Weihong Zhang, Yanyang Mo, Yan Li, Jing Bai
Summary: This study investigates the solubilization of chlorinated hydrocarbons using synthesized anionic-nonionic gemini surfactants (GEOnS-m) in an aquifer. The results show that the solubilization rate increases with the decrease of ethylene oxide content (EO) of the surfactant molecules, and the solubilization process and form depend on the polarity of the chlorinated hydrocarbons. The study advances the application of anionic-nonionic gemini surfactants in surfactant-enhanced aquifer remediation (SEAR) for chlorinated hydrocarbon solubilization, providing important insights for the design and modeling of such processes.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Matthew C. D. Carter, Daniel S. Miller, F. Joseph Schork, Tanvi S. Ratani, Tian Lan, Richard P. Woodworth, Tzu-Chi Kuo, Jason S. Fisk, Jodi M. Mecca
Summary: The incorporation of hydrophobic and sparingly water-soluble monomers into emulsion polymer particles is possible and has potential applications in high-performance coatings, adhesives, personal care products, and other functional materials. This study shows that a mixed surfactant system consisting of anionic surfactant sodium lauryl sulfate and certain nonionic surfactants enables the incorporation of hydrophobic siloxane-containing monomers into acrylic latex particles. The mixed surfactant method allows for high loading of hydrophobic monomers while minimizing undesirable macroscopic gel and large particle formation during polymerization.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Physical
Zizhao Wang, Caili Dai, Jiawei Liu, Yunbo Dong, Jinming Liu, Ning Sun, Lin Li
Summary: This study investigates the synergistic effect and enhanced oil recovery potential of a compound surfactant system composed of N, N-dihydroxyethyl alkyl amide (CDEA) and Alkylphenol polyoxyethylene carboxylate (APEC). The results reveal the importance of compound surfactant systems in EOR, as they can increase surface density, improve interfacial activity, and decrease interfacial tension, leading to enhanced oil recovery and higher oil displacement efficiency. The study also highlights the significance of understanding the interactions between surfactant molecules for practical application and optimization in oilfield development.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Biochemistry & Molecular Biology
Michael Ludwig, Ramsia Geisler, Sylvain Prevost, Regine von Klitzing
Summary: The structure characteristics of mixtures of nonionic and anionic surfactants were studied, revealing the formation of mixed micelles even at low concentrations, with excluded volume effects dominating at high volume fractions resulting in almost spherical mixed micelles formed under different mixing ratios.
Article
Chemistry, Applied
Rebecca C. Walker, Kimberly E. Penzer, Jamesa L. Stokes, Frances I. Hurwitz, Haiquan Guo, James K. Ferri
Summary: This work investigates the effects of anionic surfactant sodium dodecyl sulfate (SDS) and nonionic surfactant Pluronic (R) P-123 as templates in yttria-stabilized zirconia (YSZ) aerogels. The addition of surfactants increased the surface area and pore volume of as-dried aerogels and suppressed crystallite growth at high temperatures. However, the impact of surfactant templates on the surface area and pore volume of heat-treated aerogels was negligible, potentially due to low concentrations of surfactant and the removal of the surfactant following high-temperature exposure.
MICROPOROUS AND MESOPOROUS MATERIALS
(2023)
Article
Chemistry, Analytical
Kyle A. Brown, Morgan K. Gugger, Zhen Yu, David Moreno, Song Jin, Ying Ge
Summary: Nonionic surfactants are commonly used reagents for cell lysis and protein extraction in structural biology. However, their presence often interferes with protein analysis by electrospray ionization-mass spectrometry (ESI-MS). This study introduces a cleavable surfactant, DSSM, which is compatible with ESI-MS analysis and enables top-down proteomics characterization. DSSM can replace DDM in proteomic experiments and structural biology studies.
ANALYTICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Yingchun Xia, Ziyuan Song, Zhengzhong Tan, Tianrui Xue, Shiqi Wei, Lingyang Zhu, Yingfeng Yang, Hailin Fu, Yunjiang Jiang, Yao Lin, Yanbing Lu, Andrew L. Ferguson, Jianjun Cheng
Summary: Recent advances in accelerated polymerization of N-carboxyanhydrides (NCAs) have enriched the toolbox for preparing well-defined polypeptide materials. The use of crown ethers to catalyze NCA polymerization enables efficient preparation of functionalized polypeptides, while also guiding catalyst design.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Hao Chen, Gaurav Singhal, Frank Neubrech, Runyu Liu, Joshua S. Katz, Scott Matteucci, Steven G. Arturo, Daniel Wasserman, Harald Giessen, Paul Braun
Summary: This study demonstrates a method using plasmonic nanoantenna-based surface enhanced infrared absorption (SEIRA) to characterize molecular transport in polymers with good temporal and high spatial resolution. This method enables quantitative detection of trace quantities of compounds in thin films and diffusion measurements. The performance in terms of detection limit and detection volume is significantly improved compared to commercial systems.
Article
Engineering, Biomedical
Xu Wang, Ziyuan Song, Shiqi Wei, Guonan Ji, Xuetao Zheng, Zihuan Fu, Jianjun Cheng
Summary: Recent years have witnessed increasing interest in using ring-opening polymerization of NCAs to prepare synthetic polypeptides for various biomedical applications. Polypeptides, with their rich side-chain functionalities, diverse hydrophilicity/hydrophobicity profiles, and stable secondary structures, can assemble into well-organized nano-structures that offer unique advantages in drug delivery and controlled release. This review focuses on the design and use of polypeptide-based drug delivery systems derived from NCA chemistry, discussing their potential to change the landscape of next-generation therapeutics and diagnosis.
Article
Materials Science, Multidisciplinary
Xu Wang, Zihao Zhao, Tianrui Xue, Zhengzhong Tan, Ziyuan Song, Shiqi Wei, Yang Bo, Ying Wang, Jianjun Cheng
Summary: Ring-opening polymerization of TPE-modified NCAs was used to incorporate AIE-active segments into polypeptides, forming micelles in aqueous solution with AIE properties. The amphiphilic polypeptides show potential for formulation of doxorubicin-containing micelles for real-time drug distribution monitoring.
PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Tianjian Yang, Kyle Benson, Hailin Fu, Tianrui Xue, Ziyuan Song, Hanyi Duan, Hongwei Xia, Ankarao Kalluri, Jie He, Jianjun Cheng, Challa Kumar, Yao Lin
Summary: This study demonstrates the accelerated assembly of synthetic poly(L-glutamic acid) into amyloid-like fibrils catalyzed by cationic silica nanoparticle clusters as artificial nucleation factors. The charge-charge interactions and surface functionalities effectively facilitate the conformational change of macromolecular monomers and control the rates of nucleation for fibril growth. This approach inspires the development of novel materials through biomimetic supramolecular polymerizations.
Article
Chemistry, Medicinal
Joshua S. Katz, Danny K. Chou, Twinkle R. Christian, Tapan K. Das, Mayank Patel, Shubhadra N. Singh, Yi Wen
Summary: Biologics need to be properly formulated to withstand various destabilizing conditions they may encounter during manufacturing, transportation, storage, and use. Surfactants, such as Polysorbate 80 and Polysorbate 20, play a critical role in stabilizing protein-based biologics. However, challenges associated with traditional surfactants have prompted the development of novel surfactants. This review provides an in-depth discussion on surfactants, including their mechanisms of action, challenges, and emerging technologies for novel surfactant development.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Chemistry, Physical
Arif Z. Nelson, Yilin Wang, Yushi Wang, Anthony S. Margotta, Robert L. Sammler, Aslin Izmitli, Joshua S. Katz, Jaime Curtis-Fisk, Yongfu Li, Randy H. Ewoldt
Summary: We demonstrate that small unidirectional applied-stresses during temperature-induced gelation dramatically change the gel temperature and the resulting mechanical properties and structure of aqueous methylcellulose (MC). The applied stress makes gelation more difficult and weakens the mechanical properties of the hot gel. In extreme cases, it inhibits the formation of a fully percolated polymer network and leads to the formation of a soft granular yield-stress fluid.
Article
Polymer Science
Hailin Fu, Ryan Baumgartner, Ziyuan Song, Chongyi Chen, Jianjun Cheng, Yao Lin
Summary: This article introduces a simple kinetic model to describe the cooperativity in covalent polymerizations. By treating the growing polymer chain as both a cooperative system and a primitive enzyme, and incorporating a Michaelis-Menten-like equation, the model accurately describes the binding of monomers to the polymer chain. The application of this model can help polymer chemists discover similar cooperative mechanisms in nonpolypeptide systems and utilize them to create covalent analogues of natural cooperative systems.
Article
Polymer Science
Fangping Yang, Zhiwei Liu, Wenting Si, Ziyuan Song, Lichen Yin, Haoyu Tang
Summary: Polysaccharide-polypeptide conjugates have shown great potential for biomedical applications by mimicking the structure and bioactivity of peptidoglycans or proteoglycans. However, the efficient and precise preparation of these conjugates remains challenging. In this study, we present a facile and efficient strategy to prepare conjugates with well-controlled polypeptide chain length from unmodified polysaccharides. The effect of polypeptide chain length on the surface antibacterial properties was also investigated.
Article
Medicine, Research & Experimental
Ankit D. Kanthe, Miriam R. Carnovale, Joshua S. Katz, Susan Jordan, Mary E. Krause, Songyan Zheng, Andrew Ilott, William Ying, Wei Bu, Mrinal K. Bera, Binhua Lin, Charles Maldarelli, Raymond S. Tu
Summary: This study aimed to investigate the competitive adsorption mechanism between proteins and surfactants, finding that FM1000 saturates the interface faster than PS80 and is more effective in preventing protein adsorption.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Chenglong Ge, Junliang Zhu, Huan Ye, Yuansong Wei, Yuheng Lei, Renxiang Zhou, Ziyuan Song, Lichen Yin
Summary: In this study, a series of protein-mimetic nano-switches were constructed to control their function based on the flexibility/rigidity of the polymeric chains. When in a dormant state, the polypeptide adopts a flexible, random-coiled conformation, leading to the turn-off of the optically functional molecule. Upon treatment with alkaline phosphatase, the nano-switches are activated due to the coil-to-helix and flexible-to-rigid transition of the polypeptide linker, enabling selective fluorescence imaging or photodynamic therapy in response to ALP overproduced by tumor cells.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Wanying Wang, Hailin Fu, Yao Lin, Jianjun Cheng, Ziyuan Song
Summary: In this paper, we discussed the mechanism and applications of cooperative covalent polymerization (CCP), which can accelerate the polymerization reaction and efficiently synthesize high-molecular-weight polypeptide materials. By studying the initiating systems and kinetic models of CCP, it was found that the secondary structure and molecular interactions played a crucial role in the polymerization rate. The fast kinetics of CCP also minimized side reactions and allowed the synthesis of polypeptides in the presence of an aqueous phase.
ACCOUNTS OF MATERIALS RESEARCH
(2023)
Article
Chemistry, Medicinal
Hadi M. Fares, Miriam Carnovale, Megane O. N. Tabouguia, Susan Jordan, Joshua S. Katz
Summary: This study explores the possibility and benefits of adding FM1000, a nonionic surfactant, as a process aid in downstream processing of antibodies. FM1000 is shown to effectively stabilize proteins and prevent aggregation and fouling on surfaces. It can be easily removed if needed and flow through purification units faster compared to other surfactants. Overall, this work presents FM1000 as a versatile process aid with tunable addition and removal depending on product needs.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Polymer Science
Qinyuan Li, Yingjia Lan, Wanying Wang, Guonan Ji, Xiaohong Li, Ziyuan Song
Summary: This study reports a method to control the polymerization behavior using a cosolvent system, which alters the polymerization kinetics curve and increases monomer solubility by mixing with chloroform, enabling fast and controlled preparation of polypeptides.
Article
Materials Science, Biomaterials
Ruizhong Xue, Xu Zhang, Yuansong Wei, Ziyin Zhao, Hao Liu, Fangping Yang, Lichen Yin, Ziyuan Song, Shifang Luan, Haoyu Tang
Summary: The study reports an anionic polypeptide coating with various excellent properties, including antibacterial, antifouling, and biocompatibility. The coating, prepared through ring-opening polymerization and subsequent reaction, showed superior antibacterial activity, and in vivo studies demonstrated its good anti-infection and tissue compatibility.
BIOMATERIALS SCIENCE
(2021)
