Article
Chemistry, Analytical
Jiling Zhang, Liangwei Lu, Zhi-Ling Song, Wenjuan Song, Zhuolin Fu, Qiqi Chao, Gao-Chao Fan, Zhuo Chen, Xiliang Luo
Summary: The study developed a covalent nanoflare system using covalent amide linkages and functional Au-graphene nanoparticles for accurate detection of cancer cells and efficient photodynamic therapy.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Changding Wang, Yu Lei, Qiaoya Lv, Pinyi Wang, Weiping Kong, Fu Wan, Weigen Chen
Summary: This study reports a new high-quality catalyst composed of a trace amount of silver-supported 3D urchin-like Pd/W18O49 composite. The catalyst exhibits efficient catalytic oxidation of hydroquinone in aqueous solution, surpassing commercial catalysts. Experimental and theoretical analysis reveals that the excellent performance of this catalyst is mainly attributed to the electronic induction effect between W18O49 and Pd nanoparticles, as well as the oxygen vacancies on the surface of W18O49.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2022)
Article
Engineering, Biomedical
Wenxin Zhang, Xiaodie Li, Jialin Zeng, Xin Wen, Chao Zhang, Yinan Zhang, Jian He, Lihua Yang
Summary: This study demonstrated a dual-channel parallel free radicals-amplifying radiation therapy strategy for neuroblastoma. By releasing atovaquone (ATO) and Fe3+ in response to the tumor microenvironment, this strategy improved the effectiveness of radiation therapy by inhibiting tumor cell respiration and consuming tumor-overexpressed GSH.
MATERIALS TODAY BIO
(2023)
Article
Environmental Sciences
Lei Tang, Xiaochun Zhang, Zekai Li, Fredrick Owino Gudda, Michael Gatheru Waigi, Jian Wang, Hua Liu, Yanzheng Gao
Summary: This study optimized the remediation method of mixed persulfate and calcium peroxide system, which has high efficiency in remediation of soil contaminated with polycyclic aromatic hydrocarbons.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Engineering, Chemical
Phat Trong Huynh, Giang Dang Nguyen, Khanh Thi Le Tran, Thu Minh Ho, Vinh Quang Lam, Thanh Vo Ke Ngo
Summary: A new method using hydroquinone and chitosan to prepare multi-branched gold nanoparticles has been developed, avoiding the use of toxic surfactants and improving the shape and stability of particles through ultrasound irradiation.
Article
Chemistry, Physical
Han-Ting Chen, Dongho Lee, Suljo Linic
Summary: Bimetallic alloy nanomaterials with promising properties face the challenge of immiscibility in their synthesis. A simpler synthetic strategy involving the interaction between pulsed plasma and metal precursor salt solutions is demonstrated to rapidly form well-mixed bimetallic nanoparticles. The minimum requirements for alloy formation include high reduction rates of metal precursors for kinetic trapping, similar reduction rates for consistent mixing, and controlled nucleation to avoid burst nucleation.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yuyu Chen, Xiaobing Zeng, Yawen Liu, Rongkai Ye, Qianwei Liang, Jianqiang Hu
Summary: The study achieved structure transformation between Au-Pd alloy and core-shell icosahedral nanoparticles through a one-step aqueous-phase strategy, providing a way to modulate Pd's electronic structure and enhance its electrocatalytic ability towards the hydrogen evolution reaction.
CHEMICAL COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
S. J. Keny, A. P. Srivastava, A. K. Debnath, S. Adhikari, M. C. Rath
Summary: Uniform-sized tin oxide nanoparticles were successfully synthesized in solution using different methods. The formation of these nanoparticles was achieved through reactions between oxidizing free radicals and Sn2+ ions. Regardless of the method used, the formation pathways and sizes/shapes of the nanoparticles were similar.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Engineering, Environmental
Goutham Rangarajan, Ramin Farnood
Summary: This study reports the synthesis of H2SO4-modified biochars as solid-acid catalysts to activate H2O2 under visible light radiation. Results showed that under photo-Fenton conditions, SBC500 can achieve complete MO removal and a TOC reduction.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Inorganic & Nuclear
Hongrui Tian, Runhan Li, Jun Miao, Shuxia Liu, Fengfeng Wang, Zhiping Zheng
Summary: In this paper, a catalyst based on mixed-valence polyoxovanadate metal-organic framework (V-Cd-MOF) was reported, which can selectively oxidize aromatic alcohols to aldehydes with high yield and selectivity under additive-free conditions. The dual active sites in the polyoxovanadate cluster are responsible for the excellent catalytic performance observed.
DALTON TRANSACTIONS
(2023)
Article
Multidisciplinary Sciences
Sang Han Park, Abhishek Katoch, Keun Hwa Chae, Sanjeev Gautam, Piter Miedema, Sang Wan Cho, Minseok Kim, Ru-Pan Wang, Masoud Lazemi, Frank de Groot, Soonnam Kwon
Summary: In this study, the authors directly observed the dynamics of photo-generated holes in metal oxides using femtosecond X-ray absorption spectroscopy and identified the energy level and lifetime of these holes. They also observed the energy distribution, formation time, and decay time of trapped holes in the bandgap region of nano-crystal materials. The dynamics of electrons were also confirmed using X-ray absorption spectroscopy, providing a consistent explanation with that of the holes.
NATURE COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Liying Wu, Zhuoyu Li, Pingtong Cheng, Yuecheng She, Wei Wang, Yu Tian, Jun Ma, Zhiqiang Sun
Summary: In this study, a new type of biochar catalyst derived from a mixture of primary sludge and secondary sludge showed effective activation ability of peracetic acid. The presence of persistent free radicals was found to dominate the activation of peracetic acid. The biochar derived from the mixture of sludges had a larger specific surface area, more abundant electron-donating groups, and more defects, which promoted the formation of persistent free radicals. Furthermore, the biochar/peracetic acid system exhibited wide pH applicability and continuous stability in practical wastewater treatment.
Article
Chemistry, Multidisciplinary
Young Soo Yoon, Padmini Basumatary, Mehmet Emin Kilic, Yoo Lim Cha, Kwang-Ryeol Lee, Dong-Joo Kim, Dimpul Konwar
Summary: A novel nanosized GaPtMnP alloy anchored on N-doped multiwall carbon nanotubes was developed as an efficient electrocatalyst for ethanol fuel cells, exhibiting high activity and stability. It delivered mass and specific activities approximately 13- and 8-fold higher than Pt/C, with long-term stability and durability even after 3000 cycles. The fuel cell based on this catalyst showed a peak power density approximately fourfold higher than Pt/C, maintaining constant performance after multiple startup-shutdown cycles.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Guoming Huang, Yuan Qiu, Feifei Yang, Jiangao Xie, Xin Chen, Lili Wang, Huanghao Yang
Summary: This study introduces a novel magnetothermodynamic strategy for deep-seated tumor therapy, utilizing porous hollow iron oxide nanoparticles (PHIONs) loaded with a radical initiator (AIPH) to generate heat under an alternating magnetic field, triggering the release and decomposition of free radicals to effectively kill cancer cells under hypoxic conditions.
Article
Chemistry, Physical
Narayanamoorthy Bhuvanendran, Min Gyeong Choi, Minho Jang, Doeun Kim, Sae Youn Lee
Summary: In this study, PtRh-Co3O4 ternary alloy nanoparticles were uniformly distributed on carbon via a co-chemical reduction method. The chemical inertness of Rh and the abundant oxygen defects of Co3O4 improved the kinetics of the methanol and ethanol oxidation reactions. Compared to other Pt-based catalysts, PtRh-Co3O4/C exhibited higher CO tolerance, extended activity, and stability, making it a promising electrocatalyst for alcohol oxidation.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Analytical
Wenzhuo Chang, Yongxi Zhu, Yongjun Ma, Zhixiang Zheng, Chunming Wang
Summary: This article develops a silk-derived carbon material for the detection of chloramphenicol. This material proves to have excellent sensing performance and is successfully used in the detection of chloramphenicol in real samples.
CURRENT ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Sen Zhu, Xuan Li, Fen Wu, Xinhui Cao, Kexin Gou, Chunming Wang, Changjun Lin
Summary: Research on the phototoxicity of blue light to the skin is increasing, and it has been found that blue light induces oxidative stress, ER stress, autophagy, and apoptosis in skin cells. Exogenous hydrogen sulfide (H2S) can protect the skin from blue light-induced damage by regulating these signaling pathways.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Sen Zhu, Xuan Li, Bingrong Dang, Fen Wu, Kexin Gou, Chunming Wang, Changjun Lin
Summary: This study investigated the therapeutic effects of exogenous hydrogen sulfide (H2S) in experimental models of retinal photodamage. The results showed that H2S could alleviate blue light-induced retinal oxidative stress, apoptosis, and degeneration, and inhibit the activation of ER stress CHOP apoptotic signaling. H2S also improved blue light-induced oxidative stress and damage, and alleviated apoptosis while increasing cell viability.
Article
Biology
Zhenzhen Wang, Ziyu Zhai, Chunyu Chen, Xuejiao Tian, Zhen Xing, Panfei Xing, Yushun Yang, Junfeng Zhang, Chunming Wang, Lei Dong
Summary: Research has found that fine particulate matter (FPM) promotes lung tumor progression by inducing abnormal thickening of tissue matrix and hindering the migration of anti-tumor immune cells. These particles adsorb peroxidasin (PXDN) when inhaled into the lung, leading to an overly dense matrix. This disordered structure impairs the mobility of cytotoxic T lymphocytes and enables the growth of tumor cells. Inhibiting the activity of PXDN can eliminate the tumor-promoting effect of FPM.
Article
Chemistry, Multidisciplinary
Daping Xie, Yiming Niu, Ruoyu Mu, Senio Campos de Souza, Xiaoyu Yin, Lei Dong, Chunming Wang
Summary: The global pandemic of COVID-19 highlights the importance of vaccination. We have developed a self-adjuvant carrier based on acetyl glucomannan that activates the immune system and improves the efficacy of vaccines. In vitro and in vivo experiments have shown that this carrier enhances cellular uptake, promotes dendritic cell maturation, and boosts both humoral and cellular immune responses.
FRONTIERS IN CHEMISTRY
(2022)
Review
Pharmacology & Pharmacy
Ruohan Lou, Jiali Chen, Fei Zhou, Chunming Wang, Chung-Hang Leung, Ligen Lin
Summary: This article summarizes the role of exosomal microRNAs in promoting diabetic wound healing, as well as their targets and underlying mechanisms. Exosomal microRNAs may be an effective therapeutic approach for treating diabetic foot ulcers.
DRUG DISCOVERY TODAY
(2022)
Article
Biochemistry & Molecular Biology
Shan-Shan Hu, Ruo-Yun Li, Xin-Hui Cao, Jing-Jing Liu, Zhen-Hua Wang, Zhen Li, Mu-Lin Yang, Jia-Wei Liu, Li-Ming Hu, Chang-Jun Lin, Jing Liu, Chun-Ming Wang
Summary: Mitochondrial transplantation is a new technology that injects healthy mitochondria into damaged tissues to provide therapeutic effects. This study examines the protective effect of mitochondrial transplantation on UV irradiation-induced damage in cells and confirms the importance of mitochondrial structural integrity for its function.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Article
Medicine, Research & Experimental
Ruoyu Mu, Zhe Zhang, Congwei Han, Yiming Niu, Zhen Xing, Zhencheng Liao, Jinzhi Xu, Ningyi Shao, Guokai Chen, Junfeng Zhang, Lei Dong, Chunming Wang
Summary: Nonhealing diabetic wounds can be effectively healed by training macrophages to mimic the reparative functions of tumor-associated macrophages (TAMs), which produce immunosuppressive and proliferative factors. These TAM-educated macrophages (TAMEMs) outperform other macrophage phenotypes in reducing inflammation, promoting angiogenesis, and activating fibroblasts. A nine-factor cocktail has also been developed to train human primary monocytes into TAMEMs, enabling the preparation of safer and autologous cells. This study demonstrates the potential of recapitulating TAMs' reparative activities in non-tumor cells for regenerative medicine.
EMBO MOLECULAR MEDICINE
(2023)
Article
Engineering, Biomedical
Yuwei Li, Yu Liu, Senio Campos de Souza, Tzuwei Chao, Lei Dong, Guoxing Sun, Chunming Wang, Yiming Niu
Summary: The extent and patterns of foreign body reaction (FBR) play a significant role in the function and feasibility of biomaterials. In this study, two glucomannans with differences in glycan structure, linear-chain (Konjac glucomannan, KGM) and branched-chain (Bletilla striata polysaccharide, BSP), were used to investigate their effects on immune cells and host response. The results showed that acetyl KGM (acKGM) scaffolds induced a stronger FBR than acetyl BSP materials and could stimulate macrophages to release pro-inflammatory cytokines, providing insights for immune response regulation and biomaterials design.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Review
Medicine, Research & Experimental
Zuohao Liu, Chunming Wang, Changjun Lin
Summary: Pyroptosis is a recently discovered programmed cell death mode caused by inflammasomes and Gasdermin family proteins. It leads to the release of inflammatory factors and triggers an inflammatory cascade response. Pyroptosis has different morphological features compared to other cell death modes and can be a potential cancer treatment strategy. However, there is still much unknown about its molecular mechanisms in pathogenicity and therapeutics, requiring further research.
Article
Zoology
Wen Guo, Mengna Wang, Haotian Li, Chunming Wang
Summary: A new species of nematode, Chromadorina communis sp. nov., is described in this study. Its characteristics include: medium-sized body, finely striated cuticle with homogeneous punctations, absence of ocelli, buccal cavity with three equal-sized, solid teeth, four cephalic setae, oval amphidial fovea between cephalic setae, curved spicules with tapered distal ends, simple boat-shaped gubernaculums, five or six cup-shaped precloacal supplements, and conical tail with a very short spinneret.
Article
Chemistry, Multidisciplinary
Xiaoyu Yin, Lintao Wang, Yiming Niu, Daping Xie, Qingwen Zhang, Jian Xiao, Lei Dong, Chunming Wang
Summary: This study discovered an oligosaccharide biomaterial (OG6) that stimulates specific expression of a chemokine in macrophages, leading to hair regeneration without inducing excessive inflammation. This finding opens up new possibilities for designing glycan-based therapeutic tools.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Daping Xie, Jiaxi Chen, Chonghao Chen, Yiming Niu, Lei Dong, Chunming Wang
Summary: The emerging applications of click chemistry have provided new possibilities for understanding cellular processes and designing therapeutic tools. This study focuses on the modification of neutrophils, which are known for short lives but play a crucial role in innate immune responses. A two-step strategy involving lipid fusion and click chemical reaction is studied to engineer neutrophil surfaces with carbohydrates. Among the modified neutrophils, those modified with mannose stimulate macrophage phagocytosis, suggesting a potential approach for anti-inflammatory therapies.
ADVANCED NANOBIOMED RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Shuaifei Ji, Mingchen Xiong, Huating Chen, Yiqiong Liu, Laixian Zhou, Yiyue Hong, Mengyang Wang, Chunming Wang, Xiaobing Fu, Xiaoyan Sun
Summary: The ageing process involves the decline from cellular dysfunction to organ degeneration, resulting in increased susceptibility to deteriorated disorders. However, rejuvenation techniques, such as cellular reprogramming and epigenetic regulation, have demonstrated that ageing can be reversed or delayed. This review discusses the factors influencing cell rejuvenation, the core mechanisms involved, and the latest advancements in rejuvenation strategies. These strategies, including cellular reprogramming, removal of senescence cells, metabolic manipulation, and immune rejuvenation, have potential applications in ageing-related disease treatment.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2023)
Review
Immunology
Ruoyu Mu, Lei Dong, Chunming Wang
Summary: This article summarizes the latest trends in developing carbohydrate-containing adjuvants and discusses how the physicochemical characteristics of glycans affect their immunostimulatory functions. Additionally, potential technologies for addressing challenges in carbohydrate adjuvant design are explored from a translational perspective.
TRENDS IN IMMUNOLOGY
(2023)