期刊
ACS APPLIED MATERIALS & INTERFACES
卷 8, 期 31, 页码 19860-19865出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsami.6b05515
关键词
NGAL; human neutrophil gelatinase-associated lipocalin; field effect transistor; EG-FET; molecularly imprinted polymer; metal-organic framework; molecular docking
资金
- Polish National Science Centre (NCN) [2013/11/N/ST5/01907, 2011/01/B/ST5/03796]
- Ministry of Science and Higher Education of Poland [IP2014 041473, 0005/E-64/9/2014]
- European Research Council (ERC) [261351]
- Foundation for Polish Science
- FNP grant MISTRZ
- European Research Council (ERC) [261351] Funding Source: European Research Council (ERC)
Electropolymerizable functional and cross-linking monomers were used to prepare conducting molecularly imprinted polymer film with improved surface area with the help of a sacrificial metal organic framework (MOF). Subsequent dissolution of the MOF layer resulted in a surface developed MIP film. This surface enlargement increased the analyte accessibility to imprinted molecular cavities. Application of the porous MIP film as a recognition unit of an extended-gate field effect transistor (EG-FET) chemosensor effectively enhanced analytical current signals of determination of recombinant human neutrophil gelatinase-associated lipocalin (NGAL)
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