In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET

Sifting through the surfeit of neuroinflammation tracers

(2017) Paul Cumming et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

(2017) Giovanni B Frisoni et al.   LANCET NEUROLOGY

Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging

(2016) Lorraine Hamelin et al.   BRAIN

Novel MRI and PET markers of neuroinflammation in multiple sclerosis

(2016) Marloes Hagens et al.   CURRENT OPINION IN NEUROLOGY

Imaging of microglial activation in MS using PET: Research use and potential future clinical application

(2016) Laura Airas et al.   Multiple Sclerosis Journal

Long-term safety and efficacy of teriflunomide

(2016) Paul O'Connor et al.   NEUROLOGY

Imaging of microglial activation in MS using PET: Research use and potential future clinical application

(2016) Laura Airas et al.   Multiple Sclerosis Journal

Quantification of [18F]DPA-714 Binding in the Human Brain: Initial Studies in Healthy Controls and Alzheimer'S Disease Patients

(2015) Sandeep SV Golla et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Optimized Quantification of Translocator Protein Radioligand 18F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

(2015) S. Lavisse et al.   JOURNAL OF NUCLEAR MEDICINE

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Role of the innate and adaptive immune responses in the course of multiple sclerosis

(2015) Bernhard Hemmer et al.   LANCET NEUROLOGY

MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis—clinical implementation in the diagnostic process

(2015) Àlex Rovira et al.   Nature Reviews Neurology

Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome

(2014) Paolo Giannetti et al.   BRAIN

The Simplified Reference Tissue Model: Model Assumption Violations and Their Impact on Binding Potential

(2014) Cristian A Salinas et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In Vivo Detection of Diffuse Inflammation in Secondary Progressive Multiple Sclerosis Using PET Imaging and the Radioligand 11C-PK11195

(2014) E. Rissanen et al.   JOURNAL OF NUCLEAR MEDICINE

Could 18 F-DPA-714 PET imaging be interesting to use in the early post-stroke period?

(2014) Maria-Joao Ribeiro et al.   EJNMMI Research

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Increased PK11195 PET binding in the cortex of patients with MS correlates with disability

(2012) M. Politis et al.   NEUROLOGY

Reducing the impact of white matter lesions on automated measures of brain gray and white matter volumes

(2010) Declan T. Chard et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Folic Acid Conjugates for Nuclear Imaging of Folate Receptor-Positive Cancer

(2010) C. Muller et al.   JOURNAL OF NUCLEAR MEDICINE

Reference Tissue Models and Blood-Brain Barrier Disruption: Lessons from (R)-[11C]PK11195 in Traumatic Brain Injury

(2009) H. Folkersma et al.   JOURNAL OF NUCLEAR MEDICINE

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

(2009) William C. Kreisl et al.   NEUROIMAGE

Synthesis and Biological Evaluation of Substituted [18F]Imidazo[1,2-a]pyridines and [18F]Pyrazolo[1,5-a]pyrimidines for the Study of the Peripheral Benzodiazepine Receptor Using Positron Emission Tomography

(2008) Christopher J. R. Fookes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Reference Region Model Reveals Increased Microglial and Reduced Vascular Binding of 11C-(R)-PK11195 in Patients with Alzheimer's Disease

(2008) G. Tomasi et al.   JOURNAL OF NUCLEAR MEDICINE

DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

(2008) M. L. James et al.   JOURNAL OF NUCLEAR MEDICINE