Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

Role of Inflammation in Diabetic Retinopathy

(2018) Anne Rübsam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The microenvironment of proliferative diabetic retinopathy supports lymphatic neovascularization

(2018) Erika Gucciardo et al.   JOURNAL OF PATHOLOGY

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis

(2017) Zhiping Liu et al.   Nature Communications

Deregulation of ocular nucleotide homeostasis in patients with diabetic retinopathy

(2016) Sirpa Loukovaara et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ocular Purine Receptors as Drug Targets in the Eye

(2016) Kenneth A. Jacobson et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Purinergic signaling in retinal degeneration and regeneration

(2016) Andreas Reichenbach et al.   NEUROPHARMACOLOGY

Retinal Changes in an ATP-Induced Model of Retinal Degeneration

(2016) Felix P. Aplin et al.   Frontiers in Neuroanatomy

Polyoxometalates—Potent and selective ecto-nucleotidase inhibitors

(2015) Sang-Yong Lee et al.   BIOCHEMICAL PHARMACOLOGY

α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5′-Nucleotidase (CD73) Inhibitors

(2015) Sanjay Bhattarai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glial cell regulation of neuronal activity and blood flow in the retina by release of gliotransmitters

(2015) Eric A. Newman   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence

(2015) Rafael Simó et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Increased intravitreal adenosine 5′-triphosphate, adenosine 5′-diphosphate and adenosine 5′-monophosphate levels in patients with proliferative diabetic retinopathy

(2014) Sirpa Loukovaara et al.   ACTA OPHTHALMOLOGICA

Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities

(2014) Gennady G. Yegutkin   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Purines in the eye: Recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Müller cells, lens, trabecular meshwork, cornea and lacrimal gland

(2014) Julie Sanderson et al.   EXPERIMENTAL EYE RESEARCH

NTPDase2 and Purinergic Signaling Control Progenitor Cell Proliferation in Neurogenic Niches of the Adult Mouse Brain

(2014) Kristine Gampe et al.   STEM CELLS

Adenosine, adenosine receptors and glaucoma: An updated overview

(2013) Yisheng Zhong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Adenosine and Dopamine Receptors Coregulate Photoreceptor Coupling via Gap Junction Phosphorylation in Mouse Retina

(2013) H. Li et al.   JOURNAL OF NEUROSCIENCE

The Vitreous, the Retinal Interface in Ocular Health and Disease

(2013) Marc D. de Smet et al.   OPHTHALMOLOGICA

Dynamic Increase in Extracellular ATP Accelerates Photoreceptor Cell Apoptosis via Ligation of P2RX7 in Subretinal Hemorrhage

(2013) Shoji Notomi et al.   PLoS One

Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGFβ1 in diabetic eyes undergoing vitrectomy

(2012) Sirpa Loukovaara et al.   ACTA OPHTHALMOLOGICA

Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids

(2012) Mikko Helenius et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities

(2012) Gennady G. Yegutkin et al.   FASEB JOURNAL

Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma

(2012) Kang Zhang et al.   NATURE REVIEWS DRUG DISCOVERY

Cellular function and molecular structure of ecto-nucleotidases

(2012) Herbert Zimmermann et al.   Purinergic Signalling

Impaired ATP-Induced Coronary Blood Flow and Diminished Aortic NTPDase Activity Precede Lesion Formation in Apolipoprotein E–Deficient Mice

(2011) Nathalie Mercier et al.   AMERICAN JOURNAL OF PATHOLOGY

Adenylate Kinase and AMP Signaling Networks: Metabolic Monitoring, Signal Communication and Body Energy Sensing

(2009) Petras Dzeja et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Purinergic signaling in special senses

(2009) Gary D. Housley et al.   TRENDS IN NEUROSCIENCES

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

(2008) Gennady G. Yegutkin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Distribution of ectonucleotidases in the rodent brain revisited

(2008) David Langer et al.   CELL AND TISSUE RESEARCH

Evidence for a calcification process in the trabecular meshwork

(2008) Teresa Borrás et al.   EXPERIMENTAL EYE RESEARCH