Manipulation of Ambient Housing Temperature To Study the Impact of Chronic Stress on Immunity and Cancer in Mice

β-Adrenergic Signaling Impairs Antitumor CD8 + T-cell Responses to B-cell Lymphoma Immunotherapy

(2017) Michael D. Nissen et al.   Cancer Immunology Research

Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia

(2016) Peter J. Siska et al.   JOURNAL OF IMMUNOLOGY

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

(2016) Caroline P. Le et al.   Nature Communications

The influence of the cage environment on rodent physiology and behavior: Implications for reproducibility of pre-clinical rodent research

(2015) Linda A. Toth   EXPERIMENTAL NEUROLOGY

Molecular Mechanisms Underlying β-Adrenergic Receptor-Mediated Cross-Talk between Sympathetic Neurons and Immune Cells

(2015) Dianne Lorton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Housing Temperature–Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling

(2015) Nicholas D. Leigh et al.   JOURNAL OF IMMUNOLOGY

Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation

(2015) Jason W.-L. Eng et al.   Nature Communications

Enriched Environment Inhibits Mouse Pancreatic Cancer Growth and Down-regulates the Expression of Mitochondria-related Genes in Cancer Cells

(2015) Guohua Li et al.   Scientific Reports

Beta-Blocker Drug Therapy Reduces Secondary Cancer Formation in Breast Cancer and Improves Cancer Specific Survival

(2015)   Oncotarget

Autonomic regulation of cellular immune function

(2014) Denise L. Bellinger et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Mild cold-stress depresses immune responses: Implications for cancer models involving laboratory mice

(2014) Michelle N. Messmer et al.   BIOESSAYS

Chronic stress accelerates pancreatic cancer growth and invasion: A critical role for beta-adrenergic signaling in the pancreatic microenvironment

(2014) Corina Kim-Fuchs et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of stress on immune function: the good, the bad, and the beautiful

(2014) Firdaus S. Dhabhar   IMMUNOLOGIC RESEARCH

Translating Animal Model Research: Does It Matter That Our Rodents Are Cold?

(2014) Shane K. Maloney et al.   PHYSIOLOGY

Neuroendocrine regulation of inflammation

(2014) Caroline J. Padro et al.   SEMINARS IN IMMUNOLOGY

Improved survival outcomes with the incidental use of beta-blockers among patients with non-small-cell lung cancer treated with definitive radiation therapy

(2013) H. M. Wang et al.   ANNALS OF ONCOLOGY

A novel chronic stress-induced shift in the Th1 to Th2 response promotes colon cancer growth

(2013) Ni Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beta adrenergic blockade decreases the immunomodulatory effects of social disruption stress

(2012) M.L. Hanke et al.   BRAIN BEHAVIOR AND IMMUNITY

Impact of beta blockers on epithelial ovarian cancer survival

(2012) Elena S. Diaz et al.   GYNECOLOGIC ONCOLOGY

Physiological effects of housing density on C57BL/6J mice over a 9-month period1

(2012) B. Paigen et al.   JOURNAL OF ANIMAL SCIENCE

Unstressing intemperate models: how cold stress undermines mouse modeling

(2012) Christopher L. Karp   JOURNAL OF EXPERIMENTAL MEDICINE

Thermal physiology of laboratory mice: Defining thermoneutrality

(2012) C.J. Gordon   JOURNAL OF THERMAL BIOLOGY

Effects of Enriched Environment on COX-2, Leptin and Eicosanoids in a Mouse Model of Breast Cancer

(2012) Rachida Nachat-Kappes et al.   PLoS One

Treatment With β-Blockers and Reduced Disease Progression in Patients With Thick Melanoma

(2011) Vincenzo De Giorgi et al.   ARCHIVES OF INTERNAL MEDICINE

Molecular Pathways: Beta-Adrenergic Signaling in Cancer: Figure 1.

(2011) Steven W. Cole et al.   CLINICAL CANCER RESEARCH

Beta Blockers and Breast Cancer Mortality: A Population- Based Study

(2011) Thomas I. Barron et al.   JOURNAL OF CLINICAL ONCOLOGY

Beta-Blocker Use Is Associated With Improved Relapse-Free Survival in Patients With Triple-Negative Breast Cancer

(2011) Amal Melhem-Bertrandt et al.   JOURNAL OF CLINICAL ONCOLOGY

Social isolation is associated with elevated tumor norepinephrine in ovarian carcinoma patients

(2010) Susan K. Lutgendorf et al.   BRAIN BEHAVIOR AND IMMUNITY

The Sympathetic Nervous System Induces a Metastatic Switch in Primary Breast Cancer

(2010) E. K. Sloan et al.   CANCER RESEARCH

Environmental and Genetic Activation of a Brain-Adipocyte BDNF/Leptin Axis Causes Cancer Remission and Inhibition

(2010) Lei Cao et al.   CELL

Impact of stress on cancer metastasis

(2010) Myrthala Moreno-Smith et al.   Future Oncology

"Control" laboratory rodents are metabolically morbid: Why it matters

(2010) B. Martin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why We Should Put Clothes on Mice

(2009) Irfan J. Lodhi et al.   Cell Metabolism

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Troublesome variability in mouse studies

(2009)   NATURE NEUROSCIENCE

Stress and disorders of the stress system

(2009) George P. Chrousos   Nature Reviews Endocrinology