Computationally Designed Bispecific MD2/CD14 Binding Peptides Show TLR4 Agonist Activity

The science of vaccine adjuvants: advances in TLR4 ligand adjuvants

(2016) Steven G Reed et al.   CURRENT OPINION IN IMMUNOLOGY

Computational Discovery and Experimental Confirmation of TLR9 Receptor Antagonist Leads

(2016) Maria Zatsepin et al.   Journal of Chemical Information and Modeling

TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

(2016) Ying Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design

(2015) D. Sean Froese et al.   HUMAN MOLECULAR GENETICS

MicroScale Thermophoresis: Interaction analysis and beyond

(2014) Moran Jerabek-Willemsen et al.   JOURNAL OF MOLECULAR STRUCTURE

Rationally designed macrocyclic peptides as synergistic agonists of LPS-induced inflammatory response

(2014) Meng Gao et al.   TETRAHEDRON

The Crystal Structure of Human Soluble CD14 Reveals a Bent Solenoid with a Hydrophobic Amino-Terminal Pocket

(2012) S. L. Kelley et al.   JOURNAL OF IMMUNOLOGY

Synthetic Toll Like Receptor-4 (TLR-4) Agonist Peptides as a Novel Class of Adjuvants

(2012) Arulkumaran Shanmugam et al.   PLoS One

A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens

(2010) Anke Burger-Kentischer et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Toll-like receptor agonists in cancer therapy

(2009) Sylvia Adams   Immunotherapy

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

A Clear and Present Danger: Endogenous Ligands of Toll-like Receptors

(2009) Jacob A. Sloane et al.   NEUROMOLECULAR MEDICINE

Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

(2008) Mark R. Hutchinson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8

(2008) Jonathan Maelfait et al.   JOURNAL OF EXPERIMENTAL MEDICINE