The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer

Landscape of Phosphatidylinositol-3-Kinase Pathway Alterations Across 19 784 Diverse Solid Tumors

(2016) Sherri Z. Millis et al.   JAMA Oncology

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

(2015) Giovanni Ciriello et al.   CELL

β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis

(2015) Satdarshan Pal Monga   GASTROENTEROLOGY

Metabolic pathways promoting cancer cell survival and growth

(2015) Lindsey K. Boroughs et al.   NATURE CELL BIOLOGY

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers

(2015) Libing Xiang et al.   Oncotarget

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Gain of Interaction with IRS1 by p110α-Helical Domain Mutants Is Crucial for Their Oncogenic Functions

(2013) Yujun Hao et al.   CANCER CELL

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

Acquired PIK3CA amplification causes resistance to selective phosphoinositide 3-kinase inhibitors in breast cancer

(2013) L-Y Huw et al.   Oncogenesis

Glucose-Induced β-Catenin Acetylation Enhances Wnt Signaling in Cancer

(2012) Ana Chocarro-Calvo et al.   MOLECULAR CELL

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Transcriptional Control of Cellular Metabolism by mTOR Signaling

(2011) J. L. Yecies et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker

(2011) Kátia C. Carvalho et al.   Clinics

FOXO3a Regulates Glycolysis via Transcriptional Control of Tumor Suppressor TSC1

(2010) Shikha Khatri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer

(2009) Krishna M. Vasudevan et al.   CANCER CELL

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Glycogen Synthase Kinase-3 Inhibition Induces Glioma Cell Death through c-MYC, Nuclear Factor- B, and Glucose Regulation

(2008) S. Kotliarova et al.   CANCER RESEARCH

Surveillance FDG-PET detection of asymptomatic recurrences in patients with cervical cancer

(2008) Rebecca A. Brooks et al.   GYNECOLOGIC ONCOLOGY