Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway

The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer

(2018) Hilal Gungor et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA-101 inhibits angiogenesis via COX-2 in endometrial carcinoma

(2018) Ying Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Lippia origanoides extract induces cell cycle arrest and apoptosis and suppresses NF-κB signaling in triple-negative breast cancer cells

(2017) Vishak Raman et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers

(2017) Zhifeng Zhang et al.   PLoS One

Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1

(2016) Chengyue Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Potential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?

(2016) S Baig et al.   Cell Death & Disease

Apoptotic pathways as a therapeutic target for colorectal cancer treatment

(2016) Aman M Abraha et al.   World Journal of Gastrointestinal Oncology

BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway—A comparative study with curcumin

(2015) Kumaravel Mohankumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Histone acetyltransferase p300 is induced by p38MAPK after photodynamic therapy: the therapeutic response is increased by the p300HAT inhibitor anacardic acid

(2015) Yi-Jane Tsai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth

(2015) Jie Li et al.   OncoTargets and Therapy

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Antioxidative Dietary Compounds Modulate Gene Expression Associated with Apoptosis, DNA Repair, Inhibition of Cell Proliferation and Migration

(2014) Likui Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells

(2014) Zhenlong Yu et al.   Molecular Cancer

The HLJ1 -targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer

(2013) Yi-Hua Lai et al.   CARCINOGENESIS

Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells

(2013) Che-Yi Chao et al.   CARCINOGENESIS

MicroRNA-223 Antagonizes Angiogenesis by Targeting β1 Integrin and Preventing Growth Factor Signaling in Endothelial Cells

(2013) Lei Shi et al.   CIRCULATION RESEARCH

Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials

(2013)   LANCET

Andrographolide Protects against LPS-Induced Acute Lung Injury by Inactivation of NF-κB

(2013) Tao Zhu et al.   PLoS One

Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore

(2012) Wei Chen et al.   CARCINOGENESIS

Anti-HIV activity of semisynthetic derivatives of andrographolide and computational study of HIV-1 gp120 protein binding

(2012) Mayur M. Uttekar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status

(2011) Annika Gustafsson Asting et al.   BMC CANCER

Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway

(2011) Ko-Chen Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Inhibition of Lipopolysaccharide-Induced Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression by 4-[(2′-O-acetyl-α-L-Rhamnosyloxy)Benzyl]Isothiocyanate fromMoringa oleifera

(2011) Eun-Jung Park et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs

(2011) Sangwoon Chung et al.   PLoS One

Decreased TGFβ signaling and increased COX2 expression in high risk women with increased mammographic breast density

(2009) Wei Tse Yang et al.   BREAST CANCER RESEARCH AND TREATMENT

Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis

(2008) S R Jada et al.   BRITISH JOURNAL OF PHARMACOLOGY

Andrographolide Up-Regulates Cellular-Reduced Glutathione Level and Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury

(2008) A. Y. H. Woo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Recent advances in plant hepatoprotectives: A chemical and biological profile of some important leads

(2007) Arvind S. Negi et al.   MEDICINAL RESEARCH REVIEWS