Bacterial sepsis triggers an antiviral response that causes translation shutdown

Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule

(2018) Jordan C. Tsai et al.   SCIENCE

Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney

(2017) Takashi Hato et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Two-Photon Intravital Fluorescence Lifetime Imaging of the Kidney Reveals Cell-Type Specific Metabolic Signatures

(2017) Takashi Hato et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transcriptome-wide measurement of translation by ribosome profiling

(2017) Nicholas J. McGlincy et al.   METHODS

Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them

(2017) Kathrin Leppek et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Redefining the Translational Status of 80S Monosomes

(2016) Erin E. Heyer et al.   CELL

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

Systematic discovery of cap-independent translation sequences in human and viral genomes

(2016) Shira Weingarten-Gabbay et al.   SCIENCE

Reduction of Tubular Flow Rate as a Mechanism of Oliguria in the Early Phase of Endotoxemia Revealed by Intravital Imaging

(2015) D. Nakano et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ribosome profiling reveals the what, when, where and how of protein synthesis

(2015) Gloria A. Brar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

sORFs.org: a repository of small ORFs identified by ribosome profiling

(2015) Volodimir Olexiouk et al.   NUCLEIC ACIDS RESEARCH

The use of duplex-specific nuclease in ribosome profiling and a user-friendly software package for Ribo-seq data analysis

(2015) Betty Y. Chung et al.   RNA

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

(2015) Daniela Brina et al.   Nature Communications

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

(2015) Carmela Sidrauski et al.   eLife

Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

(2015) Dmitry E Andreev et al.   eLife

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

The Macrophage Mediates the Renoprotective Effects of Endotoxin Preconditioning

(2014) T. Hato et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

DENR–MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth

(2014) Sibylle Schleich et al.   NATURE

Quantitative profiling of initiating ribosomes in vivo

(2014) Xiangwei Gao et al.   NATURE METHODS

Mechanisms of Cardiac and Renal Dysfunction in Patients Dying of Sepsis

(2013) Osamu Takasu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE

Specialized ribosomes: a new frontier in gene regulation and organismal biology

(2012) Shifeng Xue et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Pathogenesis of Sepsis

(2011) Deborah J. Stearns-Kurosawa et al.   Annual Review of Pathology-Mechanisms of Disease

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment

(2011) R. Kalakeche et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sepsis and Acute Kidney Injury

(2011) A. Zarjou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin

(2011) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pioneer Round of Translation: Features and Functions

(2010) Lynne E. Maquat et al.   CELL

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

(2008) Valentina Gandin et al.   NATURE