Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

(2018) Marcela Brissova et al.   Cell Reports

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis

(2018) Diane C. Saunders et al.   Cell Metabolism

Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA

(2017) May Sanyoura et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

(2016) H. Efsun Arda et al.   Cell Metabolism

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes

(2016) Jenny Aurielle B Babon et al.   NATURE MEDICINE

Human islets contain four distinct subtypes of β cells

(2016) Craig Dorrell et al.   Nature Communications

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes

(2015) Martha Campbell-Thompson et al.   DIABETES

RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

(2014) Vikash Chandra et al.   Cell Reports

The many faces of diabetes: a disease with increasing heterogeneity

(2013) Tiinamaija Tuomi et al.   LANCET

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion

(2012) L. D. Pound et al.   DIABETES

Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas

(2011) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets

(2011) C. Dai et al.   DIABETOLOGIA

Maturity-onset diabetes of the young (MODY): how many cases are we missing?

(2010) B. M. Shields et al.   DIABETOLOGIA

Hnf1α (MODY3) Regulates β-Cell-Enriched MafA Transcription Factor Expression

(2010) Chad S. Hunter et al.   MOLECULAR ENDOCRINOLOGY

A genetic diagnosis ofHNF1Adiabetes alters treatment and improves glycaemic control in the majority of insulin-treated patients

(2009) M. Shepherd et al.   DIABETIC MEDICINE

Hnf1  (MODY3) Controls Tissue-Specific Transcriptional Programs and Exerts Opposed Effects on Cell Growth in Pancreatic Islets and Liver

(2009) J.-M. Servitja et al.   MOLECULAR AND CELLULAR BIOLOGY

Species-Specific Differences in the Expression of the HNF1A, HNF1B and HNF4A Genes

(2009) Lorna W. Harries et al.   PLoS One